Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Sarah Cianférani"'
Autor:
Ninon Very, Clémence Boulet, Céline Gheeraert, Alexandre Berthier, Manuel Johanns, Mohamed Bou Saleh, Loïc Guille, Fabrice Bray, Jean-Marc Strub, Marie Bobowski-Gerard, Francesco P. Zummo, Emmanuelle Vallez, Olivier Molendi-Coste, Eloise Woitrain, Sarah Cianférani, David Montaigne, Line Carolle Ntandja-Wandji, Laurent Dubuquoy, Julie Dubois-Chevalier, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-22 (2024)
Abstract Tissue injury causes activation of mesenchymal lineage cells into wound-repairing myofibroblasts (MFs), whose uncontrolled activity ultimately leads to fibrosis. Although this process is triggered by deep metabolic and transcriptional reprog
Externí odkaz:
https://doaj.org/article/7c469a228cd14e0cb8f4aa98dabc701e
Autor:
Hugo Gizardin-Fredon, Paulo E. Santo, Marie-Eve Chagot, Bruno Charpentier, Tiago M. Bandeiras, Xavier Manival, Oscar Hernandez-Alba, Sarah Cianférani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Chemical cross-linking reactions (XL) are an important strategy for studying protein-protein interactions (PPIs), including low abundant sub-complexes, in structural biology. However, choosing XL reagents and conditions is laborious and most
Externí odkaz:
https://doaj.org/article/3688e424b082493787ea3c02aaefe808
Autor:
Pierre Coliat, Stéphane Erb, Hélène Diemer, Dan Karouby, Tristan Martin, Mainak Banerjee, Chen Zhu, Martin Demarchi, Sarah Cianférani, Alexandre Detappe, Xavier Pivot
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Pneumatic transportation systems (PTS) were recently proposed as a method to carry ready-for-injection diluted monoclonal antibodies (mAbs) from the pharmacy to the bedside of patients. This method reduces transportation time and improves th
Externí odkaz:
https://doaj.org/article/2c401a85c3e245a286d2afcfc12de327
Autor:
Tony Rady, Stéphane Erb, Safia Deddouche-Grass, Renaud Morales, Guilhem Chaubet, Sarah Cianférani, Nicolas Basse, Alain Wagner
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109068- (2024)
Summary: Double-stranded RNAs (dsRNA)-based strategies appeared as promising therapies to induce an inflammation in the tumor microenvironment. However, currently described systems generally lack active targeting of tissues, and their clinical transl
Externí odkaz:
https://doaj.org/article/10ee33c87c4e491baeca79edaa602a6d
Autor:
Victor Lehot, Ondřej Lidický, Julien Most, Stéphane Erb, Igor Dovgan, Artem Osypenko, Oleksandr Koniev, Sergii Kolodych, Lenka Kotrchová, Guilhem Chaubet, Sarah Cianférani, Tomáš Etrych, Alain Wagner
Publikováno v:
ACS Omega, Vol 8, Iss 43, Pp 40508-40516 (2023)
Externí odkaz:
https://doaj.org/article/61547958d4c8422b851129ddc858ab8c
Autor:
Brice Beinsteiner, Gabriel V. Markov, Maxime Bourguet, Alastair G. McEwen, Stéphane Erb, Abdul Kareem Mohideen Patel, Fatima Z. El Khaloufi El Khaddar, Claire Lecroisey, Guillaume Holzer, Karim Essabri, Isabelle Hazemann, Ali Hamiche, Sarah Cianférani, Dino Moras, Vincent Laudet, Isabelle M. L. Billas
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Nuclear receptors are transcription factors of central importance in human biology and associated diseases. Much of the knowledge related to their major functions, such as ligand and DNA binding or dimerization, derives from funct
Externí odkaz:
https://doaj.org/article/a92389b629514a4e8a6968a1a1cd396d
Autor:
Marie Bobowski-Gerard, Clémence Boulet, Francesco P. Zummo, Julie Dubois-Chevalier, Céline Gheeraert, Mohamed Bou Saleh, Jean-Marc Strub, Amaury Farce, Maheul Ploton, Loïc Guille, Jimmy Vandel, Antonino Bongiovanni, Ninon Very, Eloïse Woitrain, Audrey Deprince, Fanny Lalloyer, Eric Bauge, Lise Ferri, Line-Carolle Ntandja-Wandji, Alexia K. Cotte, Corinne Grangette, Emmanuelle Vallez, Sarah Cianférani, Violeta Raverdy, Robert Caiazzo, Viviane Gnemmi, Emmanuelle Leteurtre, Benoit Pourcet, Réjane Paumelle, Kim Ravnskjaer, Guillaume Lassailly, Joel T. Haas, Philippe Mathurin, François Pattou, Laurent Dubuquoy, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Myofibroblasts contribute to the development of liver fibrosis. Here, the authors report that the transcription factor Basonuclin 2 (BNC2) integrates fibrogenic signals and drives myofibroblastic transcriptional activation in liver fibrosis.
Externí odkaz:
https://doaj.org/article/c0d2d56ec91641b79809fad780054395
Autor:
Victor Lehot, Patrick Neuberg, Manon Ripoll, François Daubeuf, Stéphane Erb, Igor Dovgan, Sylvain Ursuegui, Sarah Cianférani, Antoine Kichler, Guilhem Chaubet, Alain Wagner
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1643 (2023)
Despite their clinical success, Antibody-Drug Conjugates (ADCs) are still limited to the delivery of a handful of cytotoxic small-molecule payloads. Adaptation of this successful format to the delivery of alternative types of cytotoxic payloads is of
Externí odkaz:
https://doaj.org/article/3b1c23f633864d7a9b898ed3a61b0eff
Large-Scale Conformational Changes of FhaC Provide Insights Into the Two-Partner Secretion Mechanism
Autor:
Giuseppe Sicoli, Albert Konijnenberg, Jérémy Guérin, Steve Hessmann, Elise Del Nero, Oscar Hernandez-Alba, Sophie Lecher, Guillaume Rouaut, Linn Müggenburg, Hervé Vezin, Sarah Cianférani, Frank Sobott, Robert Schneider, Françoise Jacob-Dubuisson
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The Two-Partner secretion pathway mediates protein transport across the outer membrane of Gram-negative bacteria. TpsB transporters belong to the Omp85 superfamily, whose members catalyze protein insertion into, or translocation across membranes with
Externí odkaz:
https://doaj.org/article/1d8c2f861f3343c89ad6ee96c59c21e2
Autor:
Bogdan Adam Cichocki, Vrushali Khobragade, Maxime Donzel, Leandro Cotos, Stephanie Blandin, Christine Schaeffer-Reiss, Sarah Cianférani, Jean-Marc Strub, Mourad Elhabiri, Elisabeth Davioud-Charvet
Publikováno v:
JACS Au, Vol 1, Iss 5, Pp 669-689 (2021)
Externí odkaz:
https://doaj.org/article/c4db0b8f06dd4db6acb8c7d8c0d599cc