Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sarah‐Jane Leigh"'
Autor:
Cassandra E. Gheorghe, Sarah-Jane Leigh, Gabriel S.S. Tofani, Thomaz F.S. Bastiaanssen, Joshua M. Lyte, Elisa Gardellin, Ashokkumar Govindan, Conall Strain, Sonia Martinez-Herrero, Michael S. Goodson, Nancy Kelley-Loughnane, John F. Cryan, Gerard Clarke
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114079- (2024)
Summary: Chronic stress disrupts microbiota-gut-brain axis function and is associated with altered tryptophan metabolism, impaired gut barrier function, and disrupted diurnal rhythms. However, little is known about the effects of acute stress on the
Externí odkaz:
https://doaj.org/article/2451a00d25244e4ea04d5c872d5038b9
Autor:
Sarah-Jane Leigh, Nadeem O. Kaakoush, Rosa M. Escorihuela, R. Frederick Westbrook, Margaret J. Morris
Publikováno v:
Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background Exercise has been extensively utilised as an effective therapy for overweight- and obesity-associated changes that are linked to health complications. Several preclinical rodent studies have shown that treadmill exercise alongside
Externí odkaz:
https://doaj.org/article/08a887deddc24ec1a4164d48795fe003
Autor:
Serena Boscaini, Sarah-Jane Leigh, Aonghus Lavelle, Rubén García-Cabrerizo, Timothy Lipuma, Gerard Clarke, Harriët Schellekens, John F. Cryan
Publikováno v:
Molecular Metabolism, Vol 57, Iss , Pp 101427- (2022)
Background: Despite several decades of research, managing body weight remains an unsolved clinical problem. Health problems associated with dysregulated body weight, such as obesity and cachexia, exhibit several gut microbiota alterations. There is a
Externí odkaz:
https://doaj.org/article/7e5b9fe9c40443588b30d96f258dc4bc
Autor:
Michael D. Kendig, Sarah‐Jane Leigh, Kyoko Hasebe, Nadeem O. Kaakoush, R. Fred Westbrook, Margaret J. Morris
SCOPE: The effects of diet cycling on cognition and fecal microbiota are not well understood. METHOD AND RESULTS: Adult male Sprague-Dawley rats were cycled between a high-fat, high-sugar "cafeteria" diet (Caf) and regular chow. The impairment in pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f512e92a800bf324361ecd0145c74877
https://hdl.handle.net/10453/170945
https://hdl.handle.net/10453/170945
Autor:
Thomaz F. S. Bastiaanssen, Sarah-Jane Leigh, Gabriel S. S. Tofani, Cassandra E. Gheorghe, Gerard Clarke, John F. Cryan
MotivationCircadian rhythms, or 24-hour biological cycles, are key in maintaining health in almost all living organisms and synchronize important physiological and behavioural processes daily. Interest in circadian rhythm research is expanding as our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd0aeb2fa94e8824f2b777e514f4db0d
https://doi.org/10.1101/2023.04.21.537503
https://doi.org/10.1101/2023.04.21.537503
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 18:5-26
Introduction: The gut microbiota is involved in host physiology and health. Reciprocal microbiota-drug interactions are increasingly recognized as underlying some individual differences in therapy response and adverse events. Cancer pharmacotherapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e5650c777e6f17d0a6f05e62f8c62a
https://doi.org/10.1080/17425255.2022.2043849
https://doi.org/10.1080/17425255.2022.2043849
Publikováno v:
Developmental Cell. 57:1917-1919
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51a6d81b150f5f40bc528c527658c3b3
https://doi.org/10.1016/j.devcel.2022.07.013
https://doi.org/10.1016/j.devcel.2022.07.013
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-13 (2020)
Translational Psychiatry
Translational Psychiatry
Diets rich in sugar and saturated fat are associated with cognitive impairments in both humans and rodents with several potential mechanisms proposed. To test the involvement of diet-induced pro-inflammatory signaling, we exposed rats to a high-fat,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aee946f9504c2fc64107e238fcf14cc
http://link.springer.com/article/10.1038/s41398-020-0774-1
http://link.springer.com/article/10.1038/s41398-020-0774-1
Autor:
Michael D. Kendig, Kyoko Hasebe, Róisín McCague, Frances Lee, Sarah-Jane Leigh, Ria Arnold, Margaret J. Morris
Publikováno v:
Appetite. 172
Adolescence is a dynamic developmental period where unhealthy solid foods and sugar-sweetened beverages are routinely consumed. Regular consumption of solid 'junk' foods rich in fat and refined carbohydrate and sugar-sweetened beverages are independe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89d4782d20126f6ba6c900af7a7f8e7
https://pubmed.ncbi.nlm.nih.gov/35192913
https://pubmed.ncbi.nlm.nih.gov/35192913
Autor:
Serena Boscaini, Sarah-Jane Leigh, Aonghus Lavelle, Rubén García-Cabrerizo, Timothy Lipuma, Gerard Clarke, Harriët Schellekens, John F. Cryan
Publikováno v:
Molecular Metabolism, Vol 57, Iss, Pp 101427-(2022)
Background: Despite several decades of research, managing body weight remains an unsolved clinical problem. Health problems associated with dysregulated body weight, such as obesity and cachexia, exhibit several gut microbiota alterations. There is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bb2995b392d4db50cf3d613c75c0b9
https://pubmed.ncbi.nlm.nih.gov/34973469
https://pubmed.ncbi.nlm.nih.gov/34973469