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Akademický článek

Accuracy of the diagnosis of pneumonia in Canadian pediatric emergency departments: A prospective cohort study.

Autor: Joan L Robinson, James D Kellner, Jennifer Crotts, Gabino Travassos, Guanmin Chen, Valerie G Kirk, Martin Pusic, Martin Reed, Sarah Reid, Michael Weinstein, Ravi Bhargava, Maala Bhatt, Kathy Boutis, Sarah Curtis, Serge Gouin, Tim Lynch, Richard van Wylick, David W Johnson

Publikováno v: PLoS ONE, Vol 19, Iss 12, p e0311201 (2024)

BackgroundThe diagnosis of pediatric pneumonia and determination of the likely pathogen are complicated as the clinical picture overlaps with other respiratory illnesses, interpretation of radiographs is subjective, and laboratory results are rarely

Externí odkaz: https://doaj.org/article/d59508c2ea8648088e5778c882dc900f

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Akademický článek

B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

Autor: Andreas Jönsen, Sarah Reid, Christopher Sjöwall, Solbritt Rantapää-Dahlqvist, Øyvind Molberg, Dag Leonard, Maija-Leena Eloranta, Johanna K Sandling, Martina Frodlund, Karin Bolin, Anders A Bengtsson, Karoline Lerang, Anna Rudin, Anna Hedenstedt, Ahmed Sayadi, Elisabeth Skoglund

Publikováno v: Lupus Science and Medicine, Vol 10, Iss 2 (2023)

Objective B cell function and autoantibodies are important in SLE pathogenesis. In this work, we aimed to investigate the impact of cumulative SLE B cell genetics on SLE subphenotype and autoantibody profile.Methods Female patients with SLE (n=1248)

Externí odkaz: https://doaj.org/article/55b401dc6da542ab85acc67ad788d44c

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Akademický článek

Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness

Autor: Filip Segerberg, Christian Lundtoft, Sarah Reid, Karin Hjorton, Dag Leonard, Gunnel Nordmark, Mattias Carlsten, Niklas Hagberg

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Natural killer (NK) cell cytotoxicity toward self-cells is restrained by the inhibitory HLA class I-binding receptors CD94/NKG2A and the killer cell immunoglobulin-like receptors (KIRs). CD94/NKG2A and KIRs are also essential for NK cell education, w

Externí odkaz: https://doaj.org/article/a3c36f8b3b514a4a858208355caf1707

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Akademický článek

In vitro Characterization of Gut Microbiota-Derived Bacterial Strains With Neuroprotective Properties

Autor: Suaad Ahmed, Alessandro Busetti, Parthena Fotiadou, Nisha Vincy Jose, Sarah Reid, Marieta Georgieva, Samantha Brown, Hayley Dunbar, Gloria Beurket-Ascencio, Margaret I. Delday, Anna Ettorre, Imke E. Mulder

Publikováno v: Frontiers in Cellular Neuroscience, Vol 13 (2019)

Neurodegenerative diseases are disabling, incurable, and progressive conditions characterized by neuronal loss and decreased cognitive function. Changes in gut microbiome composition have been linked to a number of neurodegenerative diseases, indicat

Externí odkaz: https://doaj.org/article/891dc2d277c144c482db843a8b3b0727

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Concentration of vaginal and systemic cytokines obtained early in pregnancy and their impact on preterm birth

Autor: Christopher, Nold, Anastasia, Barros, Caroline, Rogi, Carsen, Sulzer, Angela, Quental, Sarah, Reid, Mohaned, Serdah, Anthony T, Vella

Publikováno v: The Journal of Maternal-Fetal & Neonatal Medicine. 35:9271-9276

A number of factors can lead to a maternal pro-inflammatory response resulting in a spontaneous preterm birth. However, it remains unknown if an upregulation in the maternal immune system early in pregnancy leads to an increase in pro-inflammatory cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3934b2325c922b216aa623ab9a7375
https://doi.org/10.1080/14767058.2022.2026916

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