From bench to babies – drug development for male subfertility

Autor: Shen Chuen Khaw, Sarah Martins da Silva

Publikováno v: Reproduction and Fertility, Vol 5, Iss 3, Pp 1-13 (2024)

Infertility is estimated to affect more than 50 million couples around the world, with the male factor accounting for half of these cases, yet there is a notable absence of effective treatment options for men, other than in-vitro fertilisation (IVF)

Externí odkaz: https://doaj.org/article/7243845866cc4191b0a243a90cca919c

Sperm Toolbox-A selection of small molecules to study human spermatozoa.

Autor: Franz S Gruber, Anthony Richardson, Zoe C Johnston, Rachel Myles, Neil R Norcross, David P Day, Irene Georgiou, Laura Sesma-Sanz, Caroline Wilson, Kevin D Read, Sarah Martins da Silva, Christopher L R Barratt, Ian H Gilbert, Jason R Swedlow

Publikováno v: PLoS ONE, Vol 19, Iss 2, p e0297666 (2024)

Male contraceptive options and infertility treatments are limited, and almost all innovation has been limited to updates to medically assisted reproduction protocols and methods. To accelerate the development of drugs that can either improve or inhib

Externí odkaz: https://doaj.org/article/f2f5d29a721e4ad38c065b5e3404a1c2

Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology

Autor: Lars Björndahl, Christopher L R Barratt, David Mortimer, Ashok Agarwal, Robert J Aitken, Juan G Alvarez, Natalie Aneck-Hahn, Stefan Arver, Elisabetta Baldi, Lluís Bassas, Florence Boitrelle, Riana Bornman, Douglas T Carrell, José A Castilla, Gerardo Cerezo Parra, Jerome H Check, Patricia S Cuasnicu, Sally Perreault Darney, Christiaan de Jager, Christopher J De Jonge, Joël R Drevet, Erma Z Drobnis, Stefan S Du Plessis, Michael L Eisenberg, Sandro C Esteves, Evangelini A Evgeni, Alberto Ferlin, Nicolas Garrido, Aleksander Giwercman, Ilse G F Goovaerts, Trine B Haugen, Ralf Henkel, Lars Henningsohn, Marie-Claude Hofmann, James M Hotaling, Piotr Jedrzejczak, Pierre Jouannet, Niels Jørgensen, Jackson C Kirkman Brown, Csilla Krausz, Maciej Kurpisz, Ulrik Kvist, Dolores J Lamb, Hagai Levine, Kate L Loveland, Robert I McLachlan, Ali Mahran, Liana Maree, Sarah Martins da Silva, Michael T Mbizvo, Andreas Meinhardt, Roelof Menkveld, Sharon T Mortimer, Sergey Moskovtsev, Charles H Muller, Maria José Munuce, Monica Muratori, Craig Niederberger, Cristian O’Flaherty, Rafael Oliva, Willem Ombelet, Allan A Pacey, Michael A Palladino, Ranjith Ramasamy, Liliana Ramos, Nathalie Rives, Eduardo Rs Roldan, Susan Rothmann, Denny Sakkas, Andrea Salonia, Maria Cristina Sánchez-Pozo, Rosanna Sapiro, Stefan Schlatt, Peter N Schlegel, Hans-Christian Schuppe, Rupin Shah, Niels E Skakkebæk, Katja Teerds, Igor Toskin, Herman Tournaye, Paul J Turek, Gerhard van der Horst, Monica Vazquez-Levin, Christina Wang, Alex Wetzels, Theodosia Zeginiadou, Armand Zini

Publikováno v: HUMAN REPRODUCTION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Human Reproduction, 37, 2497-2502
Human Reproduction
Human Reproduction, 2022, 37 (11), pp.2497-2502. ⟨10.1093/humrep/deac189⟩
Björndahl, L, Barratt, C L R, Mortimer, D, Agarwal, A, Aitken, R J, Alvarez, J G, Aneck-Hahn, N, Arver, S, Baldi, E, Bassas, L, Boitrelle, F, Bornman, R, Carrell, D T, Castilla, J A, Cerezo Parra, G, Check, J H, Cuasnicu, P S, Darney, S P, de Jager, C, De Jonge, C J, Drevet, J R, Drobnis, E Z, Du Plessis, S S, Eisenberg, M L, Esteves, S C, Evgeni, E A, Ferlin, A, Garrido, N, Giwercman, A, Goovaerts, I G F, Haugen, T B, Henkel, R, Henningsohn, L, Hofmann, M C, Hotaling, J M, Jedrzejczak, P, Jouannet, P, Jørgensen, N, Kirkman Brown, J C, Krausz, C, Kurpisz, M, Kvist, U, Lamb, D J, Levine, H, Loveland, K L, McLachlan, R I, Mahran, A, Maree, L, Martins da Silva, S, Mbizvo, M T, Meinhardt, A, Menkveld, R, Mortimer, S T, Moskovtsev, S, Muller, C H, Munuce, M J, Muratori, M, Niederberger, C, O'Flaherty, C, Oliva, R, Ombelet, W, Pacey, A A, Palladino, M A, Ramasamy, R, Ramos, L, Rives, N, Roldan, E R, Rothmann, S, Sakkas, D, Salonia, A, Sánchez-Pozo, M C, Sapiro, R, Schlatt, S, Schlegel, P N, Schuppe, H C, Shah, R, Skakkebæk, N E, Teerds, K, Toskin, I, Tournaye, H, Turek, P J, van der Horst, G, Vazquez-Levin, M, Wang, C, Wetzels, A, Zeginiadou, T & Zini, A 2022, ' Standards in semen examination : publishing reproducible and reliable data based on high-quality methodology ', Human Reproduction, vol. 37, no. 11, pp. 2497-2502 . https://doi.org/10.1093/humrep/deac189
Human reproduction (Oxford, England) 37 (2022) 11
Human reproduction
Human reproduction (Oxford, England), 37(11), 2497-2502
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen examination. Recently two concorda

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7218b3fb5ad10d580776ec380f57e6bc
https://doi.org/10.1093/humrep/deac189

Should patients pay for sperm given for free? Results from a pilot study on fertility clinics’ views on the charging for altruistically donated sperm

Autor: Emma Rowlinson, Sarah Martins Da Silva, Nkoyenum Pamela Olisa, Lisa Campo-Engelstein

Publikováno v: Journal of Assisted Reproduction and Genetics.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a47343059f809aaf3c573390ed302694
https://doi.org/10.1007/s10815-023-02776-1

Reproductive Axis Ageing and Fertility in Men

Autor: Sarah Martins da Silva, Richard A Anderson

Publikováno v: Martins da Silva, S J & Anderson, R A 2022, ' Reproductive Axis Ageing and Fertility in Men ', Reviews in Endocrine and Metabolic Disorders . https://doi.org/10.1007/s11154-022-09759-0

Compared to women, increasing male age is not accompanied by such marked changes in reproductive function but changes certainly do happen. These include alterations to the hypothalamo-pituitary-testicular axis, with resultant implications for testost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1f27f83f1baed712b73adb8b0f45b8
https://www.pure.ed.ac.uk/ws/files/299746035/Reproductive_Axis_Aging_and_Fertility_in_Men_final.docx