Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Sarah, Jenna"'
Autor:
Talia Roseshter, Anna Klemantovich, Luca Cavallone, Adriana Aguilar-Mahecha, Josiane Lafleur, Oluwadara O. Elebute, Sarah Jenna, Jean-Francois Boileau, Manuela Pelmus, Mark Basik, Cathy Lan
Publikováno v:
Cancer Research. 83:P2-11
Background The presence of residual tumour at surgery (non-pathological complete response or non-pCR) occurs in about half of TNBCs treated with neoadjuvant chemotherapy (NAC) and signals chemoresistance and poor prognosis. Although further adjuvant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57cb5400123ee52fe598d8231b4da501
https://doi.org/10.1158/1538-7445.sabcs22-p2-11-26
https://doi.org/10.1158/1538-7445.sabcs22-p2-11-26
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 2, p e1004738 (2016)
A genetic interaction (GI) is defined when the mutation of one gene modifies the phenotypic expression associated with the mutation of a second gene. Genome-wide efforts to map GIs in yeast revealed structural and functional properties of a GI networ
Externí odkaz:
https://doaj.org/article/f22117daa49d438886edcb436887c1ec
Autor:
Audrey Kapelanski-Lamoureux, Migmar Tsamchoe, Lucyna Krzywon, Jessica Bloom, Julie Cardin, Stephanie K Petrillo, Zu-hua Gao, Sarah Jenna, Anthoula Lazaris, Peter Metrakos
Publikováno v:
Journal of Clinical Oncology. 41:252-252
252 Background: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in North America with over 50% of CRC patients developing liver metastases (LM) and 90% will die from metastatic disease. CRCLM are categorized into two main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec48bc7fafaf4c76468781e25661b4c3
https://doi.org/10.1200/jco.2023.41.4_suppl.252
https://doi.org/10.1200/jco.2023.41.4_suppl.252
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94684 (2014)
Cell shape changes are crucial for metazoan development. During Caenorhabditis elegans embryogenesis, epidermal cell shape changes transform ovoid embryos into vermiform larvae. This process is divided into two phases: early and late elongation. Earl
Externí odkaz:
https://doaj.org/article/75dbc093e0494ca093d212b146d16d85
Autor:
Adriana Aguilar-Mahecha, Yasamin Majedi, Oluwadara Elebute, Josiane Lafleur, Andreas Papadakis, Cathy Lan, Manuela Pelmus, Touhidur Rashid, Sarah Jenna, Mark Basik
Publikováno v:
Cancer Research. 82:4011-4011
Background: Triple negative breast cancer is the most aggressive type of breast cancer. Approximately 50% of TNBC patients respond to pre-operative neo-adjuvant chemotherapy (NAC), however those patients with residual disease (non-pathological comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::615eb31b39b401a05924eb253033f756
https://doi.org/10.1158/1538-7445.am2022-4011
https://doi.org/10.1158/1538-7445.am2022-4011
Publikováno v:
Cancer Research. 82:6375-6375
Introduction: Basal-like breast cancer (BLBC; TNBC) cells use aerobic glycolysis at a higher rate than Luminal A (LumA) cells. Metabolic reprogramming using aerobic glycolysis (Warburg effect), is correlated with increased aggressiveness of cancer ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088cf910d1651c522b7c77a6f8bd4014
https://doi.org/10.1158/1538-7445.am2022-6375
https://doi.org/10.1158/1538-7445.am2022-6375
Publikováno v:
Journal of Clinical Oncology. 40:3123-3123
3123 Background: Precision oncology is growing rapidly in parallel with advances in high throughput sequencing. Development of new anti-cancer therapies is, however, still associated with low efficacy issues, leading to phase II and III clinical tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe42161290286856c78559d824328478
https://doi.org/10.1200/jco.2022.40.16_suppl.3123
https://doi.org/10.1200/jco.2022.40.16_suppl.3123
Autor:
Anna Y Lee, Richard Perreault, Sharon Harel, Elodie L Boulier, Matthew Suderman, Michael Hallett, Sarah Jenna
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10624 (2010)
BackgroundThe symptoms of numerous diseases result from genetic mutations that disrupt the homeostasis maintained by the appropriate integration of signaling gene activities. The relationships between signaling genes suggest avenues through which hom
Externí odkaz:
https://doaj.org/article/cfafbc64268f4960ac6a62ee18e8b454
Autor:
Michel Bouvier, Marie-Pierre Dubé, Sylvie Perreault, Sarah Jenna, B. White-Guay, Jean-Lucien Rouleau, Simon de Denus, Richard Leduc, Jean-Claude Tardif, Marc Dorais, Michel White, Denis deBlois, Benjamin Haibe-Kains
Publikováno v:
Pharmacoepidemiology and Drug Safety. 26:81-90
Purpose The long-term use of β-blockers has been shown to improve clinical outcomes among patients with heart failure (HF). However, a lack of data persists in assessing whether carvedilol or bisoprolol are superior to metoprolol tartrate in clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f129a5a0e763fcefaffaf6e945d25521
https://doi.org/10.1002/pds.4132
https://doi.org/10.1002/pds.4132
Publikováno v:
Journal of Molecular Cell Biology. 8:313-327
Collective epithelial cell migration requires the maintenance of cell–cell junctions while enabling the generation of actin-rich protrusions at the leading edge of migrating cells. Ventral enclosure of Caenorhabditis elegans embryos depends on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e8923cec3aa03d25fc54b3c1a34714
https://doi.org/10.1093/jmcb/mjv062
https://doi.org/10.1093/jmcb/mjv062