Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Saraf R Ramesh"'
Many myofibrillar proteins undergo isoform switching in a spatio-temporal manner during muscle development. The biological significance of the variants of several of these myofibrillar proteins remains elusive. One such myofibrillar protein, the Musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155de47891b649c0d7ccd14a8d0d5d8c
https://doi.org/10.1101/2021.12.18.473287
https://doi.org/10.1101/2021.12.18.473287
Publikováno v:
Biogerontology. 20:497-513
Longevity of a species is a multifactorial quantitative trait influenced by genetic background, sex, age and environment of the organism. Extended longevity phenotypes (ELP) from experimental evolution in the laboratory can be used as model systems t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224aca3d4e57ee8cdf5fdde2a5b771a9
https://doi.org/10.1007/s10522-019-09812-7
https://doi.org/10.1007/s10522-019-09812-7
Publikováno v:
Parkinson's Disease
Parkinson's Disease, Vol 2021 (2021)
Parkinson's Disease, Vol 2021 (2021)
Parkinson’s disease (PD) is an age-associated neurodegenerative condition in which some genetic variants are known to increase disease susceptibility on interaction with environmental factors inducing oxidative stress. Different mutations in the SN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c8a5b2ecb470b033b9aeedfecdd92b
Parkinson’s disease (PD) is a class of neurodegenerative disorders in which, complex interactions of genetic and environmental agents are involved in the etiology of both sporadic and familial PD cases. α-synuclein-encodingSNCAgene is known as one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb85392e30597fb984f9d0e042c7f279
Publikováno v:
Journal of Basic and Applied Zoology, Vol 73, Iss C, Pp 1-8 (2016)
We have attempted to identify the chromosomal region harboring genes encoding major glue fractions by correlating the glue protein synthesis with the puffing pattern of the X-chromosome of Drosophila nasuta nasuta during normal larval development and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c08d75711dd140e31ca524d2322afb
https://doi.org/10.1016/j.jobaz.2015.08.001
https://doi.org/10.1016/j.jobaz.2015.08.001
Autor:
Upendra Nongthomba, Hena Firdaus, Jayaram Mohan, Sarwat Naz, Saraf R. Ramesh, Prabhashankar Arathi
Publikováno v:
Genetics. 200:149-165
Rapid and high wing-beat frequencies achieved during insect flight are powered by the indirect flight muscles, the largest group of muscles present in the thorax. Any anomaly during the assembly and/or structural impairment of the indirect flight mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c98a2d33c9e38c6a88183f961ac466
https://doi.org/10.1534/genetics.115.175604
https://doi.org/10.1534/genetics.115.175604
Publikováno v:
Neurochemistry International. 80:1-6
Overexpression of human α-synuclein gene in Drosophila can reduce lifespan, and we have performed lifespan assay for A30P and A53Tα-synuclein transgenic and control (elav-GAL4, UAS-A30P, UAS-A53T) flies. Our results showed reduced lifespan of trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96844df229cb478aaaf82595a4999dd3
https://doi.org/10.1016/j.neuint.2014.10.010
https://doi.org/10.1016/j.neuint.2014.10.010
Publikováno v:
Neurochemical research. 42(11)
Exposure to pesticides like paraquat (PQ) is considered as a risk factor for Parkinson's disease (PD). PQ has been shown to induce PD-like phenotype in experimental animals. Drosophila, a valuable laboratory model organism, is widely used to study ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbecd3510478330f975628fdbc7afff7
https://pubmed.ncbi.nlm.nih.gov/29318482
https://pubmed.ncbi.nlm.nih.gov/29318482
Publikováno v:
Current aging science. 11(1)
BACKGROUND Although genetic variations are heritable, some quantitative traits like longevity may have non-genomic influence on heritability. Laboratory-selected inbred strains of extended longevity phenotype of Drosophila offer an opportunity to stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a3b8fc861eb5e8982982629a24ad22
https://pubmed.ncbi.nlm.nih.gov/28641508
https://pubmed.ncbi.nlm.nih.gov/28641508
Publikováno v:
Current aging science. 10(3)
Background: Aging or senescence is a complex biological phenomenon. Artificially selected Drosophila for extended longevity is one of the experimental models used to understand the mechanisms involved in aging and to test various theories. Objective:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ea2669515d5091b1c73da464c7bd3e
https://pubmed.ncbi.nlm.nih.gov/28183243
https://pubmed.ncbi.nlm.nih.gov/28183243