Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Saradhadevi Varadharaj"'
Endocannabinoid System and Its Regulation by Polyunsaturated Fatty Acids and Full Spectrum Hemp Oils
Autor:
Slavko Komarnytsky, Thirumurugan Rathinasabapathy, Charles Wagner, Brandon Metzger, Carolina Carlisle, Chinmayee Panda, Sara Le Brun-Blashka, John P. Troup, Saradhadevi Varadharaj
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5479 (2021)
The endocannabinoid system (ECS) consists of endogenous cannabinoids, their receptors, and metabolic enzymes that play a critical homeostatic role in modulating polyunsaturated omega fatty acid (PUFA) signaling to maintain a balanced inflammatory and
Externí odkaz:
https://doaj.org/article/52fec72f52c247f786d23a953c2447d9
Autor:
Xiaoping Liu, Mohamed A. El-Mahdy, James Boslett, Saradhadevi Varadharaj, Craig Hemann, Tamer M. Abdelghany, Raed S. Ismail, Sean C. Little, Danlei Zhou, Le Thi Thanh Thuy, Norifumi Kawada, Jay L. Zweier
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The gaseous signalling molecule nitric oxide regulates vascular tone. Here, the authors show that nitric oxide is degraded by the enzyme cytoglobin in the vascular wall, and that mice lacking cytoglobin have reduced blood pressure and are less sensit
Externí odkaz:
https://doaj.org/article/7c48b88ebe1f45628a4d604983c1bc11
Autor:
David C. Nieman, Arnoud J. Groen, Artyom Pugachev, Andrew J. Simonson, Kristine Polley, Karma James, Bassem F. El-Khodor, Saradhadevi Varadharaj, Claudia Hernández-Armenta
Publikováno v:
Proteomes, Vol 8, Iss 1, p 4 (2020)
Proteomics monitoring of an elite adventure athlete (age 33 years) was conducted over a 28-week period that culminated in the successful, solo, unassisted, and unsupported two month trek across the Antarctica (1500 km). Training distress was monitore
Externí odkaz:
https://doaj.org/article/525a0ad3f2004210a3bc2f2543de5579
Publikováno v:
Nutrients, Vol 12, Iss 2, p 540 (2020)
A-F Betafood® is a whole food-based health product. The product contains phytonutrients and bioactives with antioxidant properties that may support gallbladder and liver function. Herein, we investigated the efficacy of A-F Betafood® on gallbladder
Externí odkaz:
https://doaj.org/article/eedaa6353d984cbd998e4e0d5eb36417
Autor:
Saradhadevi Varadharaj, Owen J. Kelly, Rami N. Khayat, Purnima S. Kumar, Naseer Ahmed, Jay L. Zweier
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 4 (2017)
In vascular diseases, including hypertension and atherosclerosis, vascular endothelial dysfunction (VED) occurs secondary to altered function of endothelial nitric oxide synthase (eNOS). A novel redox regulated pathway was identified through which eN
Externí odkaz:
https://doaj.org/article/61496ceda7184cc7b329df99a6bfbcab
Autor:
Binata Joddar, Michael S Firstenberg, Rashmeet K Reen, Saradhadevi Varadharaj, Mahmood Khan, Rachel C Childers, Jay L Zweier, Keith J Gooch
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120301 (2015)
Saphenous veins used as arterial grafts are exposed to arterial levels of oxygen partial pressure (pO2), which are much greater than what they experience in their native environment. The object of this study is to determine the impact of exposing hum
Externí odkaz:
https://doaj.org/article/ececd30ea95a4e7aa44188596b0df137
Autor:
Narasimham L. Parinandi, Alex Liaugminas, Patrick J. Oliver, Saradhadevi Varadharaj, Anita Yenigalla, Austin C. Elliott, Sukruthi Arutla, Steven J. Campbell, Sainath R. Kotha, Shariq I. Sherwani, Vijay K. Kutala, Jodi C. McDaniel, Krishna Rao Maddipati, Periannan Kuppusamy, Thomas J. Hund
Publikováno v:
Cell Biochemistry and Biophysics.
Autor:
Saradhadevi Varadharaj, Lakshmi Narasimhan Chakrapani, Ashokkumar Srinivasan, Thangarajeswari Mohan, Periandavan Kalaiselvi, Prema Velusamy, Abhilasha Singh, S N Kishore Kumar, Divya Bhavani Ravi
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Cardiac hypertrophy is the underlying cause of heart failure and is characterized by excessive oxidative stress leading to collagen deposition. Therefore, understanding the signalling mechanisms involved in excessive extracellular matrix deposition i
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 176
Polyunsaturated fatty acids (PUFAs) are long chain fatty acids that are characterized by the presence of more than one double bond. These include fatty acids such as ꞷ-3-α-linolenic acid (ALA) and ꞷ-6 –linoleic acid (LA) which can only be obta
Endocannabinoid System and Its Regulation by Polyunsaturated Fatty Acids and Full Spectrum Hemp Oils
Autor:
Charles Wagner, Sara Le Brun-Blashka, Slavko Komarnytsky, Carolina Carlisle, Thirumurugan Rathinasabapathy, Saradhadevi Varadharaj, Brandon Metzger, John P Troup, Chinmayee Panda
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5479, p 5479 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 5479, p 5479 (2021)
The endocannabinoid system (ECS) consists of endogenous cannabinoids, their receptors, and metabolic enzymes that play a critical homeostatic role in modulating polyunsaturated omega fatty acid (PUFA) signaling to maintain a balanced inflammatory and