Zobrazeno 1 - 10 of 46 pro vyhledávání: '"Sarada Subramanian"'
1
Akademický článek
Development of a dot blot assay with antibodies to recombinant 'core' 14-3-3 protein: Evaluation of its usefulness in diagnosis of Creutzfeldt–Jakob disease
Autor: Sarada Subramanian, Anita Mahadevan, Parthasarathy Satishchandra, Susarla Krishna Shankar
Publikováno v: Annals of Indian Academy of Neurology, Vol 19, Iss 2, Pp 205-210 (2016)
Background and Purpose: Definitive diagnosis of Creutzfeldt–Jakob disease (CJD) requires demonstration of infective prion protein (PrPSc) in brain tissues by immunohistochemistry or immunoblot, making antemortem diagnosis of CJD difficult. The Worl
Externí odkaz: https://doaj.org/article/4cfd2fa5759b47fba26945185502f061
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2
Akademický článek
In vitro screening for anti-cholinesterase and antioxidant activity of methanolic extracts of ayurvedic medicinal plants used for cognitive disorders.
Autor: Maya Mathew, Sarada Subramanian
Publikováno v: PLoS ONE, Vol 9, Iss 1, p e86804 (2014)
Inhibition of Acetylcholinesterase (AChE) is still considered as the main therapeutic strategy against Alzheimer's disease (AD). Many plant derived phytochemicals have shown AChE inhibitory activity in addition to the currently approved drugs for AD.
Externí odkaz: https://doaj.org/article/adf8037dc0a741b5a2ae0e36c38d8c9b
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3
Pathological (Dis)Similarities in Neuronal Exosome-Derived Synaptic and Organellar Marker Levels Between Alzheimer’s Disease and Frontotemporal Dementia
Autor: Geethu, Krishna, Rashmi, Santhoshkumar, Palanimuthu Thangaraju, Sivakumar, Suvarna, Alladi, Anita, Mahadevan, Ajit B, Dahale, Faheem, Arshad, Sarada, Subramanian
Publikováno v: Journal of Alzheimer's Disease. :1-11
Background: Alzheimer’s disease (AD) and frontotemporal dementia (FTD) are pathologically distinct neurodegenerative disorders with certain overlap in cognitive and behavioral symptoms. Both AD and FTD are characterized by synaptic loss and accumul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f302261df002551c74cd716b89d2b7c2
https://doi.org/10.3233/jad-220829
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6
Increased prolidase activity in Alzheimer's dementia: A case-control study
Autor: Mathew Varghese, Ajit Bhalchandra Dahale, Thomas Gregor Issac, Geethu Krishna, Anu Kn Unni, Preeti Sinha, Palanimuthu T. Sivakumar, Shiva Shanker Reddy Mukku, Sarada Subramanian, Lakshmi Prabha M
Publikováno v: Asian journal of psychiatry. 53
Prolidase enzyme, which catalyzes the final step in collagen metabolism can influence the cognitive functions through changes in extracellular matrix (ECM) resulting in altered synaptic connectivity in Alzheimer's disease (AD). In this study, it was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a943ff9c1cb241909858fef53657ed
https://pubmed.ncbi.nlm.nih.gov/32590139
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7
Plasma neurofilament L to amyloid β42 ratio in differentiating Alzheimer’s type from non-Alzheimer’s dementia: A cross-sectional pilot study from India
Autor: Sarada Subramanian, Palanimuthu T. Sivakumar, Mathew Varghese, Ajit Bhalchandra Dahale, Susheel Kumar J, Preeti Sinha, Geethu Krishna
Publikováno v: Asian Journal of Psychiatry. 66:102914
Based on the reduction of amyloid β plaques, US FDA has recently approved Aducanumab as a disease modifying treatment for Alzheimer's disease (AD). With high pricing and the potential risks likely with this treatment, certainty of AD diagnosis becom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a033bdb4e720a7974b3605e1c904cf80
https://doi.org/10.1016/j.ajp.2021.102914
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9
Passive immunization targeting the N-terminal region of phosphorylated tau (residues 68–71) improves spatial memory in okadaic acid induced tauopathy model rats
Autor: Ganesh Savanur, Sowmya Madhavadas, Sarada Subramanian
Publikováno v: Biochemical and Biophysical Research Communications. 483:585-589
Alzheimer's disease (AD) is the leading cause of dementia, characterized by progressive loss of memory and other cognitive functions. The cognitive impairment in patients with AD is closely associated with loss of synapses and the formation of neurof
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1e649bb9e5acdd7a94771b24f0a510
https://doi.org/10.1016/j.bbrc.2016.12.101
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10
Development of a dot blot assay with antibodies to recombinant 'core' 14-3-3 protein: Evaluation of its usefulness in diagnosis of Creutzfeldt–Jakob disease
Autor: Anita Mahadevan, Parthasarathy Satishchandra, Sarada Subramanian, Susarla K. Shankar
Publikováno v: Annals of Indian Academy of Neurology
Annals of Indian Academy of Neurology, Vol 19, Iss 2, Pp 205-210 (2016)
Background and Purpose: Definitive diagnosis of Creutzfeldt–Jakob disease (CJD) requires demonstration of infective prion protein (PrPSc) in brain tissues by immunohistochemistry or immunoblot, making antemortem diagnosis of CJD difficult. The Worl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43a99ed325faa8fe94a2ba223891d45
http://europepmc.org/articles/PMC4888683
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