Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sarabjeet Kour Sudan"'
Autor:
Kunwar Somesh Vikramdeo, Shashi Anand, Sarabjeet Kour Sudan, Paramahansa Pramanik, Seema Singh, Andrew K. Godwin, Ajay Pratap Singh, Santanu Dasgupta
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 10, Pp 412-426 (2023)
Abstract Early detection and recurrence prediction are challenging in triple‐negative breast cancer (TNBC) patients. We aimed to develop mitochondrial DNA (mtDNA)‐based liquid biomarkers to improve TNBC management. Mitochondrial genome (MG) enric
Externí odkaz:
https://doaj.org/article/c9d72767779a4643a181e3a028f8e7f0
Autor:
Haiping Liu, Haixiang Ma, Xingyue Zeng, Chengyan Wu, Srijan Acharya, Sarabjeet Kour Sudan, Xiaohan Zhang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10031 (2023)
A class-A GPCR dopamine D2 receptor (D2R) plays a critical role in the proper functioning of neuronal circuits through the downstream activation of both G-protein- and β-arrestin-dependent signaling pathways. Understanding the signaling pathways dow
Externí odkaz:
https://doaj.org/article/285088d4e1b941c2b11c001749c45814
Autor:
Kunwar Somesh Vikramdeo, Amod Sharma, Shashi Anand, Sarabjeet Kour Sudan, Seema Singh, Ajay Pratap Singh, Santanu Dasgupta
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4482 (2023)
Prostate cancer (PCa) affects millions of men worldwide and is a major cause of cancer-related mortality. Race-associated PCa health disparities are also common and are of both social and clinical concern. Most PCa is diagnosed early due to PSA-based
Externí odkaz:
https://doaj.org/article/798347b32cd54b1c81808e61bbaf8227
Autor:
Shashi Anand, Mohammad Aslam Khan, Haseeb Zubair, Sarabjeet Kour Sudan, Kunwar Somesh Vikramdeo, Sachin Kumar Deshmukh, Shafquat Azim, Sanjeev Kumar Srivastava, Seema Singh, Ajay Pratap Singh
Publikováno v:
EMBO reports. 24
Extensive desmoplasia and poor vasculature renders pancreatic tumors severely hypoxic, contributing to their aggressiveness and therapy resistance. Here, we identify the HuR/MYB/HIF1α axis as a critical regulator of the metabolic plasticity and hypo
Autor:
Rodney P. Rocconi, Seema Singh, Kunwar Somesh Vikramdeo, Mohammad Aslam Khan, Santanu Dasgupta, Sarabjeet Kour Sudan, Annelise M. Wilhite, Ajay P. Singh
Publikováno v:
Semin Cancer Biol
Resistance to platinum-based chemotherapy is a major clinical challenge in ovarian cancer, contributing to the high mortality-to-incidence ratio. Management of the platinum-resistant disease has been difficult due to diverse underlying molecular mech
Publikováno v:
Journal of cellular physiologyREFERENCES. 237(11)
Mitochondria are pivotal organelles that govern cellular energy production through the oxidative phosphorylation system utilizing five respiratory complexes. In addition, mitochondria also contribute to various critical signaling pathways including a
Autor:
Shashi Anand, Mohammad Aslam Khan, Haseeb Zubair, Sarabjeet Kour Sudan, Kunwar Somesh Vikramdeo, Sachin Kumar Deshmukh, Shafquat Azim, Sanjeev Kumar Srivastava, Seema Singh, Ajay Pratap Singh
Publikováno v:
Cancer Research. 82:2351-2351
Pancreatic ductal adenocarcinoma exhibits high degree of intratumoral hypoxia due to its unique histopathological features contributing to its extremely aggressive nature and unusual chemoresistance. It is however not yet very clear what drives and s
Autor:
Amod Sharma, Kunwar Somesh Vikramdeo, Sarabjeet Kour Sudan, Sachin Kumar Deshmukh, Ajay P. Singh, Seema Singh
Publikováno v:
Cancer Research. 82:1546-1546
Cortisol, the primary stress hormone, can contribute to cancer development through a variety of mechanisms. In a population-based research study, we have detected high serum levels of cortisol and several exosomal microRNAs (miRs) in women with a bre
Autor:
Vinay Randhawa, Sarabjeet Kour Sudan, Deepika Pal, Shanmugam Mayilraj, Manoj Kumar, Narender Kumar, Girish Sahni, Amit Kumar Gupta
Publikováno v:
Microbial drug resistance (Larchmont, N.Y.). 27(10)
In the present study, we have analyzed the metagenomic DNA from the pooled sediment sample of the river Ganges to explore the abundance and diversity of phages, microbial community and antibiotic resistance genes. Utilizing data from Illumina platfor
Autor:
Donna Lynn Dyess, Teja Poosarla, Sarabjeet Kour Sudan, Nicolette Holliday, Sachin Kumar Deshmukh, Seema Singh, Ajay P. Singh
Publikováno v:
Biochim Biophys Acta Rev Cancer
Systemic and organ-confined inflammation has been associated with cancer development and progression. Resistin, initially described as an adipocyte-derived cytokine in mice, is mostly expressed by the macrophages in humans. It has potent pro-inflamma