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Autor:
Maria Rosa eLopez-Huertas, Jasmine eLi, Anjum eZafar, Sara eRodriguez-Mora, Carlota eGarcía-Domínguez, Elena eMateos, Jose eAlcami, Sudha eRao, Mayte eCoiras
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
PKCtheta is essential for the activation of CD4+ T cells. Upon TCR/CD28 stimulation, PKCtheta is phosphorylated and migrates to the immunological synapse, inducing the activation of cellular transcription factors such as NF-kB and kinases as ERK that
Externí odkaz:
https://doaj.org/article/a66da0aaa7c44d19b63ab145e5852068
