Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sara Westrøm"'
Autor:
Roxanne Wouters, Sara Westrøm, Yani Berckmans, Matteo Riva, Jolien Ceusters, Tina B. Bønsdorff, Ignace Vergote, An Coosemans
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
A novel alpha-therapy consisting of 224Ra-labeled calcium carbonate microparticles (224Ra-CaCO3-MP) has been designed to treat micrometastatic peritoneal disease via intraperitoneal (IP) administration. This preclinical study aimed to evaluate its ef
Externí odkaz:
https://doaj.org/article/293bce168e4649ebab737b967704a0ad
Autor:
Elisa Napoli, Tina B Bønsdorff, Ida Sofie Jorstad, Øyvind S Bruland, Roy H Larsen, Sara Westrøm
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248133 (2021)
Alpha-particle emitting radionuclides continue to be the subject of medical research because of their high energy and short range of action that facilitate effective cancer therapies. Radium-224 (224Ra) is one such candidate that has been considered
Externí odkaz:
https://doaj.org/article/57f6abd6c1334c3da0817dd0bb88c727
Autor:
Roxanne Wouters, Sara Westrøm, Ann Vankerckhoven, Gitte Thirion, Jolien Ceusters, Sandra Claes, Dominique Schols, Tina B. Bønsdorff, Ignace Vergote, An Coosemans
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 687 (2022)
Novel treatment strategies are needed to provide a better prognosis for ovarian cancer. For this purpose, the current study was designed to evaluate the effects of different types of particle drug carriers on tumor response and on the tumor immune mi
Externí odkaz:
https://doaj.org/article/5f614b79901e4a00a523057f41007f26
Publikováno v:
Translational Oncology, Vol 11, Iss 2, Pp 259-267 (2018)
BACKGROUND: Ovarian cancer patients with chemotherapy-resistant residual microscopic disease in the peritoneal cavity have a considerable need for new treatment options. Alpha-emitting radionuclides injected intraperitoneally may be an attractive the
Externí odkaz:
https://doaj.org/article/a7ef52998f6b4dce8f53d4c8ebae2cd2
Autor:
Ruth Gong Li, Kim Lindland, Sandra Karen Tonstad, Tina Bjørnlund Bønsdorff, Asta Juzeniene, Sara Westrøm, Roy Hartvig Larsen
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 634 (2021)
Radium-224-labeled CaCO3 microparticles have been developed to treat peritoneal carcinomatosis. The microparticles function as carriers of 224Ra, facilitating intraperitoneal retention of the alpha-emitting radionuclide. It was necessary to control t
Externí odkaz:
https://doaj.org/article/b3dc548547314f128e150f0d496e85d6
Autor:
Sara Westrøm, Tina B Bønsdorff, Nasir Abbas, Øyvind S Bruland, Thora J Jonasdottir, Gunhild M Mælandsmo, Roy H Larsen
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165382 (2016)
Osteosarcoma is a rare form of cancer but with a substantial need for new active drugs. There is a particular need for targeted therapies to combat metastatic disease. One possible approach is to use an antibody drug conjugate or an antibody radionuc
Externí odkaz:
https://doaj.org/article/8ac6b49b86b141f79b46ea949f48e3ff
Autor:
Asta Juzeniene, Ida Sofie Jorstad, Sara Westrøm, Tina Bjørnlund Bønsdorff, Ruth Gong Li, Elisa Napoli, Øyvind S. Bruland, Roy H. Larsen
Publikováno v:
Current Radiopharmaceuticals. 14:145-153
Background: Patients with advanced-stage ovarian cancer face a poor prognosis because of recurrent peritoneal cavity metastases following surgery and chemotherapy. Alpha-emitters may enable the efficient treatment of such disseminated diseases becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1dd21cd5f96bd30f4e55683594ccfe
https://doi.org/10.2174/1874471013666201201102056
https://doi.org/10.2174/1874471013666201201102056
Autor:
Sandra Karen Tonstad, Sara Westrøm, Asta Juzeniene, Ruth Gong Li, Kim Lindland, Tina Bjørnlund Bønsdorff, Roy H. Larsen
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 634, p 634 (2021)
Volume 13
Issue 5
Pharmaceutics, Vol 13, Iss 634, p 634 (2021)
Volume 13
Issue 5
Radium-224-labeled CaCO3 microparticles have been developed to treat peritoneal carcinomatosis. The microparticles function as carriers of 224Ra, facilitating intraperitoneal retention of the alpha-emitting radionuclide. It was necessary to control t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6756389658390009959dd995445ff58
http://europepmc.org/articles/PMC8145685
http://europepmc.org/articles/PMC8145685
Publikováno v:
Materials
Materials, Vol 14, Iss 7130, p 7130 (2021)
Materials; Volume 14; Issue 23; Pages: 7130
Materials, Vol 14, Iss 7130, p 7130 (2021)
Materials; Volume 14; Issue 23; Pages: 7130
Lead-212 is recognized as a promising radionuclide for targeted alpha therapy for tumors. Many studies of 212Pb-labeling of various biomolecules through bifunctional chelators have been conducted. Another approach to exploiting the cytotoxic effect i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9543d03dde99a6bb03cdecde9923bc96
http://hdl.handle.net/10852/92881
http://hdl.handle.net/10852/92881
Autor:
Roy H. Larsen, Ida Sofie Jorstad, Sara Westrøm, Øyvind S. Bruland, Tina Bjørnlund Bønsdorff, Elisa Napoli
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0248133 (2021)
PLoS ONE, Vol 16, Iss 3, p e0248133 (2021)
Alpha-particle emitting radionuclides continue to be the subject of medical research because of their high energy and short range of action that facilitate effective cancer therapies. Radium-224 (224Ra) is one such candidate that has been considered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::552d7ef9ff0a028e882ad2c51d85b798
https://pubmed.ncbi.nlm.nih.gov/33662039
https://pubmed.ncbi.nlm.nih.gov/33662039