Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Sara W. Feigelson"'
Autor:
Anita Sapoznikov, Stav Kozlovski, Nehora Levi, Sara W. Feigelson, Ofer Regev, Natalia Davidzohn, Shifra Ben-Dor, Rebecca Haffner-Krausz, Ester Feldmesser, Noa Wigoda, Ekaterina Petrovich-Kopitman, Moshe Biton, Ronen Alon
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112864- (2023)
Summary: Lymphocyte priming in lymph nodes (LNs) was postulated to depend on the formation of stable T cell receptor (TCR)-specific immune synapses (ISs) with antigen (Ag)-presenting dendritic cells (DCs). The high-affinity LFA-1 ligand ICAM-1 was im
Externí odkaz:
https://doaj.org/article/67139ba272364b81bc07233d20deeb03
Autor:
Stav Kozlovski, Ofer Regev, Anita Sapoznikov, Marina Kizner, Hagit Achdout, Ekaterina Petrovich-Kopitman, Jacob Elkahal, Yoseph Addadi, Fernanda Vargas E. Silva Castanheira, Sara W. Feigelson, Paul Kubes, Noam Erez, Natalio Garbi, Ronen Alon
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
αLβ2 (LFA-1) mediated interactions with ICAM-1 and ICAM-2 predominate leukocyte-vascular interactions, but their functions in extravascular cell-cell communications is still debated. The roles of these two ligands in leukocyte trafficking, lymphocy
Externí odkaz:
https://doaj.org/article/42ff2249db14402eaf642c4f20e2336e
Autor:
Shirsendu Ghosh, Vincenzo Di Bartolo, Liron Tubul, Eyal Shimoni, Elena Kartvelishvily, Tali Dadosh, Sara W. Feigelson, Ronen Alon, Andres Alcover, Gilad Haran
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3434-3447.e6 (2020)
Summary: T cell surfaces are covered with microvilli, actin-rich and flexible protrusions. We use super-resolution microscopy to show that ≥90% of T cell receptor (TCR) complex molecules TCRαβ and TCRζ, as well as the co-receptor CD4 (cluster of
Externí odkaz:
https://doaj.org/article/f150b30a4f764bdbae634a217f5fa452
Autor:
Adi Sagiv, Amir Bar-Shai, Naama Levi, Miki Hatzav, Lior Zada, Yossi Ovadya, Lior Roitman, Gal Manella, Ofer Regev, Julia Majewska, Ezra Vadai, Raya Eilam, Sara W. Feigelson, Michael Tsoory, Michel Tauc, Ronen Alon, Valery Krizhanovsky
Publikováno v:
Cell Reports, Vol 22, Iss 13, Pp 3468-3479 (2018)
Summary: The tumor suppressor p53 limits tumorigenesis by inducing apoptosis, cell cycle arrest, and senescence. Although p53 is known to limit inflammation during tumor development, its role in regulating chronic lung inflammation is less well under
Externí odkaz:
https://doaj.org/article/3f1c19548e7f4fcf87e7ad6139d3663b
ICAMs Are Not Obligatory for Functional Immune Synapses between Naive CD4 T Cells and Lymph Node DCs
Autor:
Sara W. Feigelson, Adam Solomon, Adi Biram, Miki Hatzav, Moria Lichtenstein, Ofer Regev, Stav Kozlovski, Diana Varol, Caterina Curato, Dena Leshkowitz, Steffen Jung, Ziv Shulman, Ronen Alon
Publikováno v:
Cell Reports, Vol 22, Iss 4, Pp 849-859 (2018)
Protective immune responses depend on the formation of immune synapses between T cells and antigen-presenting cells (APCs). The two main LFA-1 ligands, ICAM-1 and ICAM-2, are co-expressed on many cell types, including APCs and blood vessels. Although
Externí odkaz:
https://doaj.org/article/862946718f1948919dc67c1968e7dbd8
Autor:
Sagi Barzilai, Sandeep Kumar Yadav, Steven Morrell, Francesco Roncato, Eugenia Klein, Liat Stoler-Barak, Ofra Golani, Sara W. Feigelson, Assaf Zemel, Sussan Nourshargh, Ronen Alon
Publikováno v:
Cell Reports, Vol 18, Iss 3, Pp 685-699 (2017)
The endothelial cytoskeleton is a barrier for leukocyte transendothelial migration (TEM). Mononuclear and polymorphonuclear leukocytes generate gaps of similar micron-scale size when squeezing through inflamed endothelial barriers in vitro and in viv
Externí odkaz:
https://doaj.org/article/10960c2cd30d4e339fbdac6278b6f396
Autor:
Gilad Haran, Shirsendu Ghosh, Ronen Alon, Carlo Laudanna, Eyal Shimoni, Francesco Roncato, Daniel F. Legler, Alessio Montresor, Sara W. Feigelson
Publikováno v:
Biophys J
Leukocyte microvilli are elastic actin-rich projections implicated in rapid sensing and penetration across glycocalyx barriers. Microvilli are critical for the capture and arrest of flowing lymphocytes by high endothelial venules, the main lymph node
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd3e2094732e895e99109af60bd17cb
https://doi.org/10.1016/j.bpj.2021.08.014
https://doi.org/10.1016/j.bpj.2021.08.014
Autor:
Noa Wigoda, Anita Sapoznikov, Anika Grafen, Ester Feldmesser, Ronen Alon, Moshe Biton, Sara W. Feigelson, Ekaterina Petrovich-Kopitman, Natalia Davidzohn, Stav Kozlovski
Lymphocyte priming in lymph nodes (LNs) depends on the formation of functional TCR specific immune synapses (ISs) with antigen (Ag) presenting dendritic cells. The high affinity LFA-1 ligand ICAM-1 has been implicated in different ISs studiedin vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::002d6151ddace183084e6b7e0ea28b04
https://doi.org/10.1101/2021.10.27.466043
https://doi.org/10.1101/2021.10.27.466043
Autor:
Ronen Alon, Darko Stojkov, Sara W. Feigelson, Shida Yousefi, Francesco Roncato, Sandeep Kumar Yadav, Hans-Uwe Simon
Publikováno v:
Journal of Leukocyte Biology. 105:755-766
Microtubules (MTs) are critically involved in the transport of material within cells, but their roles in chemotactic leukocyte motility and effector functions are still obscure. Resting neutrophils contain few MTs assembled in an MT organizing center
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3d797e8f9d73e3834629f00ff6bc08
https://doi.org/10.1002/jlb.3a1118-437rr
https://doi.org/10.1002/jlb.3a1118-437rr
Autor:
Ofer Regev, Ronen Alon, Yossi Ovadya, Francesco Roncato, Gabi Gerlitz, Sandeep Kumar Yadav, Yoseph Addadi, Ester Feldmesser, Sérgio F. de Almeida, Marina Kizner, Nehora Levi, João C. Sabino, Diana Drago-Garcia, Sara W. Feigelson, Lukasz Kaczmarczyk, Samuel Ovadia
Publikováno v:
Cancers
Volume 13
Issue 10
Cancers, Vol 13, Iss 2383, p 2383 (2021)
Volume 13
Issue 10
Cancers, Vol 13, Iss 2383, p 2383 (2021)
Simple Summary The nucleus is the largest and stiffest organelle of tumor cells. Cancer metastasis depends on the ability of cancer cells circulating in the blood to exit blood vessels and survive in target organs. The roles of the shell (lamina) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb4cde374b3cc606ddb62fe3710b3fa
https://lirias.kuleuven.be/handle/123456789/683271
https://lirias.kuleuven.be/handle/123456789/683271