Partial Genetic Deletion of Klotho Aggravates Cardiac Calcium Mishandling in Acute Kidney Injury

Autor: Laura González-Lafuente, José Alberto Navarro-García, Ángela Valero-Almazán, Elena Rodríguez-Sánchez, Sara Vázquez-Sánchez, Elisa Mercado-García, Patricia Pineros, Jonay Poveda, María Fernández-Velasco, Makoto Kuro-O, Luis M. Ruilope, Gema Ruiz-Hurtado

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 2, p 1322 (2023)

Acute kidney injury (AKI) is associated with an elevated risk of cardiovascular major events and mortality. The pathophysiological mechanisms underlying the complex cardiorenal network interaction remain unresolved. It is known that the presence of A

Externí odkaz: https://doaj.org/article/6869b39e948f406b864bc9d8640b2cd2

Oxidized Low-Density Lipoprotein Associates with Ventricular Stress in Young Adults and Triggers Intracellular Ca2+ Alterations in Adult Ventricular Cardiomyocytes

Autor: Elena Rodríguez-Sánchez, José Alberto Navarro-García, Laura González-Lafuente, Jennifer Aceves-Ripoll, Sara Vázquez-Sánchez, Jonay Poveda, Elisa Mercado-García, Nerea Corbacho-Alonso, Eva Calvo-Bonacho, María Fernández-Velasco, Gloria Álvarez-Llamas, María G. Barderas, Luis M. Ruilope, Gema Ruiz-Hurtado

Publikováno v: Antioxidants, Vol 9, Iss 12, p 1213 (2020)

Oxidized low-density lipoprotein (oxLDL) is associated with cardiac damage and causes injury to multiple cell types. We aimed to investigate the role of oxLDL in ventricular stress. We first examined the association between circulating oxLDL and N-te

Externí odkaz: https://doaj.org/article/c53d8fecb98c4102bb54fb12366e9654

Interplay between mineral bone disorder and cardiac damage in acute kidney injury: from Ca

Autor: Laura, González-Lafuente, José Alberto, Navarro-García, Elena, Rodríguez-Sánchez, Jennifer, Aceves-Ripoll, Jonay, Poveda, Sara, Vázquez-Sánchez, Elisa, Mercado-García, María, Fernández-Velasco, Makoto, Kuro-O, Fernando, Liaño, Luis M, Ruilope, Gema, Ruiz-Hurtado

Publikováno v: Translational research : the journal of laboratory and clinical medicine. 243

Biomarkers of mineral bone disorders (MBD) including phosphorus, fibroblast growth factor (FGF)-23 and Klotho are strongly altered in patients with acute kidney injury (AKI) who have high cardiac outcomes and mortality rates. However, the crosslink b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::87d052ff2acb76638e4447bd92385e20
https://pubmed.ncbi.nlm.nih.gov/35077866

Oxidized Low-Density Lipoprotein Associates with Ventricular Stress in Young Adults and Triggers Intracellular Ca2+ Alterations in Adult Ventricular Cardiomyocytes

Autor: Gema Ruiz-Hurtado, Elena Rodríguez-Sánchez, Maria G. Barderas, Nerea Corbacho-Alonso, Jennifer Aceves-Ripoll, Sara Vázquez-Sánchez, Eva Calvo-Bonacho, José Alberto Navarro-García, Luis M. Ruilope, Laura González-Lafuente, Elisa Mercado-García, María Fernández-Velasco, Jonay Poveda, Gloria Alvarez-Llamas

Publikováno v: Antioxidants, Vol 9, Iss 1213, p 1213 (2020)
Antioxidants
Volume 9
Issue 12
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)

Oxidized low-density lipoprotein (oxLDL) is associated with cardiac damage and causes injury to multiple cell types. We aimed to investigate the role of oxLDL in ventricular stress. We first examined the association between circulating oxLDL and N-te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256791c5153e363556bb28d8da8cadce
https://doi.org/10.3390/antiox9121213