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Autor:
Philip E. Branton, Suiyang Li, Marie-Joëlle Miron, Olivier Binda, Helen Chan, Richard C. Marcellus, David C. Pallas, Danita G. Ashby, Claudine Brignole, Sara Thirlwell, Zhiying Zhang, Monica McQuoid
Publikováno v:
Journal of Virology. 83:8340-8352
Human adenovirus E4orf4 protein is toxic in human tumor cells. Its interaction with the Bα subunit of protein phosphatase 2A (PP2A) is critical for cell killing; however, the effect of E4orf4 binding is not known. Bα is one of several mammalian B-t