Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sara Santagata"'
Autor:
Luigi Portella, Giulia Bertolini, Giuseppe Guardascione, Dario Guido Di Febbraro, Caterina Ieranò, Crescenzo D'Alterio, Giuseppina Rea, Maria Napolitano, Sara Santagata, Anna Maria Trotta, Rosa Camerlingo, Emilia Scarpa, Sabrina Chiara Cecere, Alessandro Ottaiano, Giuliano Palumbo, Alessandro Morabito, Teresa Somma, Giuseppe De Rosa, Laura Mayol, Roberto Pacelli, Sandro Pignata, Stefania Scala
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35524- (2024)
Background: Circulating Tumor Cells (CTCs) represent a small, heterogeneous population that comprise the minority of cells able to develop metastasis. To trap and characterize CTCs with metastatic attitude, a CXCL12-loaded hyaluronic-gel (CLG) was de
Externí odkaz:
https://doaj.org/article/7a5251e405c146bc825e22f84743a27f
Autor:
Alessandro Ottaiano, Antonella De Luca, Mariachiara Santorsola, Giosuè Scognamiglio, Annabella Di Mauro, Paolo Chiodini, Matilde Lambiase, Alessandra Sacco, Antonella Petrillo, Vincenza Granata, Roberta Fusco, Edoardo Mercadante, Nicola Martucci, Giuseppe De Luca, Antonello La Rocca, Egidio Celentano, Anna Crispo, Piergiacomo Di Gennaro, Fabiana Tatangelo, Gerardo Ferrara, Francesco Izzo, Andrea Belli, Renato Patrone, Paolo Delrio, Daniela Rega, Silvia De Franciscis, Paolo Muto, Vincenzo Ravo, Rossella Di Franco, Valentina Borzillo, Sara Santagata, Giuseppina Rea, Daniela Castaldo, Ugo Pace, Gianfranco De Feo, Stefania Scala, Guglielmo Nasti, Nicola Normanno
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Metastatic disease in tumors originating from the gastrointestinal tract can exhibit varying degrees of tumor burden at presentation. Some patients follow a less aggressive disease course, characterized by a limited number of meta
Externí odkaz:
https://doaj.org/article/0f8b4dec1455442a95550e330fb15be2
Autor:
Nicola Normanno, Fabiana Tatangelo, Piera Maiolino, Stefania Scala, Caterina Ieranò, Dario Righelli, Crescenzo D'Alterio, Maria Napolitano, Luigi Portella, Giuseppina Rea, Federica Auletta, Sara Santagata, Anna Maria Trotta, Giuseppe Guardascione, Federica Liotti, Nella Prevete, Antonio Luciano, Antonio Barbieri, Annabella Di Mauro, Cristin Roma, Riziero Esposito Abate, Roberto Pacelli, Rosa Marina Melillo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Colorectal cancer (CRC) is one of the most prevalent and deadly tumors worldwide. The majority of CRC is resistant to anti-programmed cell death-1 (PD-1)-based cancer immunotherapy, with approximately 15% with high-microsatellite instabili
Externí odkaz:
https://doaj.org/article/b1c66c6327b04eacbccc9f2e0878a6d9
Autor:
Sara Santagata, Caterina Ieranò, Anna Maria Trotta, Anna Capiluongo, Federica Auletta, Giuseppe Guardascione, Stefania Scala
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The chemokine receptor 4 (CXCR4) and 7 (CXCR7) are G-protein-coupled receptors (GPCRs) activated through their shared ligand CXCL12 in multiple human cancers. They play a key role in the tumor/tumor microenvironment (TME) promoting tumor progression,
Externí odkaz:
https://doaj.org/article/140e32ae85c94a27a45f6b2adf8fe91d
Autor:
Anna Maria Trotta, Sara Santagata, Serena Zanotta, Crescenzo D’Alterio, Maria Napolitano, Giuseppina Rea, Rosa Camerlingo, Fabio Esposito, Elvira Lamantia, Annamaria Anniciello, Giovanni Botti, Nicola Longo, Gerardo Botti, Sandro Pignata, Sisto Perdonà, Stefania Scala
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-12 (2018)
Abstract Background Previous evidence demonstrated that restoration of wild type VHL in human renal cancer cells decreased in vitro NK susceptibility. To investigate on the role of tumoral VHL status versus NK capability in renal cancer patients, 51
Externí odkaz:
https://doaj.org/article/530e6c500afe42ebb3d9c021de8d75e4
Autor:
Alessandro Ottaiano, Angela Petito, Mariachiara Santorsola, Valerio Gigantino, Maurizio Capuozzo, Daniela Fontanella, Rossella Di Franco, Valentina Borzillo, Sergio Buonopane, Vincenzo Ravo, Esmeralda Scipilliti, Giuseppe Totaro, Marcello Serra, Gianluca Ametrano, Roberta Penta, Fabiana Tatangelo, Giosuè Scognamiglio, Annabella Di Mauro, Maurizio Di Bonito, Maria Napolitano, Stefania Scala, Giuseppina Rea, Sara Santagata, Angela Lombardi, Anna Grimaldi, Carlo Caputo, Anna Crispo, Egidio Celentano, Gianfranco De Feo, Luisa Circelli, Giovanni Savarese, Raffaella Ruggiero, Francesco Perri, Vincenza Granata, Gerardo Botti, Michele Caraglia, Guglielmo Nasti, Paolo Muto
Publikováno v:
Cancers, Vol 13, Iss 16, p 4236 (2021)
Background: in recent years, the management of advanced colorectal cancer (CRC) has been greatly improved with integrated strategies including stereotactic radiation therapy (SRT). The administration of SRT has been demonstrated, particularly in olig
Externí odkaz:
https://doaj.org/article/841a0cee7f914a61a318aea7d88038ad
Autor:
Sara Santagata, Luigi Portella, Maria Napolitano, Adelaide Greco, Crescenzo D’Alterio, Maria Vittoria Barone, Antonio Luciano, Matteo Gramanzini, Luigi Auletta, Claudio Arra, Antonella Zannetti, Stefania Scala
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract C-X-C chemokine receptor 4 (CXCR4) is over-expressed in multiple human cancers and correlates with tumor aggressiveness, poor prognosis and increased risk for distant metastases. Imaging agents for CXCR4 are thus highly desirable. We develop
Externí odkaz:
https://doaj.org/article/2e67fe00267c494d87da49165cfcd85e
Autor:
Crescenzo D’Alterio, Antonella Zannetti, Anna Maria Trotta, Caterina Ieranò, Maria Napolitano, Giuseppina Rea, Adelaide Greco, Piera Maiolino, Sandra Albanese, Giosuè Scognamiglio, Fabiana Tatangelo, Salvatore Tafuto, Luigi Portella, Sara Santagata, Guglielmo Nasti, Alessandro Ottaiano, Roberto Pacelli, Paolo Delrio, Gerardo Botti, Stefania Scala
Publikováno v:
Cancers, Vol 12, Iss 7, p 1952 (2020)
The chemokine receptor CXCR4 is overexpressed and functional in colorectal cancer. To investigate the role of CXCR4 antagonism in potentiating colon cancer standard therapy, the new peptide CXCR4 antagonist Peptide R (Pep R) was employed. Human colon
Externí odkaz:
https://doaj.org/article/e54c138d205243cabfb0177061ae5ed3
Autor:
M Vittoria Barone, Delia Zanzi, Mariantonia Maglio, Merlin Nanayakkara, Sara Santagata, Giuliana Lania, Erasmo Miele, Maria Teresa Silvia Ribecco, Francesco Maurano, Renata Auricchio, Carmen Gianfrani, Silvano Ferrini, Riccardo Troncone, Salvatore Auricchio
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17039 (2011)
BACKGROUND AND OBJECTIVES: Damage to intestinal mucosa in celiac disease (CD) is mediated both by inflammation due to adaptive and innate immune responses, with IL-15 as a major mediator of the innate immune response, and by proliferation of crypt en
Externí odkaz:
https://doaj.org/article/2165793ec5b14af4a0452e72c67e00fb
Autor:
Maria Vittoria Barone, Merlin Nanayakkara, Giovanni Paolella, Mariantonia Maglio, Virginia Vitale, Raffaele Troiano, Maria Teresa Silvia Ribecco, Giuliana Lania, Delia Zanzi, Sara Santagata, Renata Auricchio, Riccardo Troncone, Salvatore Auricchio
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12246 (2010)
BACKGROUND: Celiac Disease (CD) is both a frequent disease (1:100) and an interesting model of a disease induced by food. It consists in an immunogenic reaction to wheat gluten and glutenins that has been found to arise in a specific genetic backgrou
Externí odkaz:
https://doaj.org/article/014170044703444987db08df387d0028