Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sara S Alhakeem"'
Autor:
Karine Z Oben, Beth W Gachuki, Sara S Alhakeem, Mary K McKenna, Ying Liang, Daret K St Clair, Vivek M Rangnekar, Subbarao Bondada
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169767 (2017)
An understanding of how each individual 5q chromosome critical deleted region (CDR) gene contributes to malignant transformation would foster the development of much needed targeted therapies for the treatment of therapy related myeloid neoplasms (t-
Externí odkaz:
https://doaj.org/article/4bcd361048fb4b30a37263d3c348d29a
Autor:
James P. Collard, Mary K. McKenna, Sunil K. Noothi, Sara S. Alhakeem, Jacqueline R. Rivas, Vivek M. Rangnekar, Natarajan Muthusamy, Subbarao Bondada
Publikováno v:
Leukemia & Lymphoma. 63:1810-1822
The chronic lymphocytic leukemia (CLL) microenvironment has been receiving an increasing amount of attention, but there is currently limited data surrounding how the microenvironment affects initial development of CLL. We determined that the spleen i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1eddd657d553309959bf664036a9991
https://doi.org/10.1080/10428194.2022.2045596
https://doi.org/10.1080/10428194.2022.2045596
Autor:
Jon S. Thorson, Sara S. Alhakeem, Gerhard C. Hildebrandt, Subbarao Bondada, Yinan Zhang, Natarajan Muthusamy, Khaled A. Shaaban, Yang Liu, Li Chen, Francesc Marti, James P. Collard, Markos Leggas, Jacqueline R. Rivas, Roger A. Fleischman, Joseph M. Eckenrode
Publikováno v:
Leukemia
T-cell dysfunction is a hallmark of B-cell Chronic Lymphocytic Leukemia (CLL), where CLL cells downregulate T-cell responses through regulatory molecules including programmed death ligand-1 (PD-L1) and Interleukin-10 (IL-10). Immune checkpoint blocka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875756f8c1c3f12adc69a704f3b1ca84
http://europepmc.org/articles/PMC8446094
http://europepmc.org/articles/PMC8446094
Autor:
Wendy A. Spencer, Sara S. Alhakeem, Farrukh Aqil, Raghuram Kandimalla, Ramesh C. Gupta, Neha Tyagi, Jun Yan, Ashish Kumar Agrawal, Subbarao Bondada, Jeyaprakash Jeyabalan
Publikováno v:
Cancers
Volume 13
Issue 15
Cancers, Vol 13, Iss 3700, p 3700 (2021)
Volume 13
Issue 15
Cancers, Vol 13, Iss 3700, p 3700 (2021)
Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small-cell lung cancer (NSCLC) is the most common type accounting for 84% of all lung cancers. Paclitaxel (PAC) is a widely used drug in the treatment of a broad spectrum of hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45571afd04b52693ac25d68ba50ae630
Autor:
Sunil K. Noothi, Mary K. McKenna, Sara S. Alhakeem, James P. Collard, J. T. Greene, Natarajan Muthusamy, Vivek M. Rangnekar, Subbarao Bondada
Publikováno v:
Tumor Suppressor Par-4 ISBN: 9783030805579
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::738d265e50e9cf8876353990c6cc46b4
https://doi.org/10.1007/978-3-030-80558-6_8
https://doi.org/10.1007/978-3-030-80558-6_8
Autor:
Vivek M. Rangnekar, Roger A. Fleischman, Subbarao Bondada, Jacqueline R. Rivas, Sara S. Alhakeem, Sunil K. Noothi, Gerhard C. Hildebrandt, Natarajan Muthusamy, Mary K. McKenna, Karine Z. Oben
Publikováno v:
The Journal of Immunology. 200:4180-4189
Chronic lymphocytic leukemia (CLL) patients progressively develop an immunosuppressive state. CLL patients have more plasma IL-10, an anti-inflammatory cytokine, than healthy controls. In vitro human CLL cells produce IL-10 in response to BCR cross-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee72eb699900507564f41b609d45ff63
https://doi.org/10.4049/jimmunol.1800241
https://doi.org/10.4049/jimmunol.1800241
Autor:
Karine Z. Oben, Subbarao Bondada, Ahmed Abdel-Latif, Sunil K. Noothi, Sara S. Alhakeem, Ramesh C. Gupta, Natarajan Muthusamy, Jason A. Brandon, Liu Jinpeng, Daret K. St. Clair, Sanjit K. Dhar, Harold F. Stills, Kaoru Tohyama, Rajeswaran Mani, Chi Wang, Shailaja Akunuru, Mary K. McKenna, Ying Liang, Hartmut Geiger, Inder Pal Singh
Publikováno v:
Oncotarget
// Karine Z. Oben 1 , Sara S. Alhakeem 1 , Mary K. McKenna 1 , Jason A. Brandon 2 , Rajeswaran Mani 3 , Sunil K. Noothi 1 , Liu Jinpeng 4 , Shailaja Akunuru 5 , Sanjit K. Dhar 6 , Inder P. Singh 7 , Ying Liang 6 , Chi Wang 4 , Ahmed Abdel-Latif 2 , H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ca32055a1a62ef78e46a2bb370eb18
http://europepmc.org/articles/PMC5652791
http://europepmc.org/articles/PMC5652791
Autor:
Suriyan Sukati, Sara S. Alhakeem, Heidi L. Weiss, D. Allan Butterfield, Hannah Thompson, Chontida Yarana, Subbarao Bondada, Daret K. St. Clair, Luksana Chaiswing
Publikováno v:
Redox Biology
Redox Biology, Vol 26, Iss, Pp-(2019)
Redox Biology, Vol 26, Iss, Pp-(2019)
Extracellular vesicles (EVs) generated from redox active anticancer drugs are released into the extracellular environment. These EVs contain oxidized molecules and trigger inflammatory responses by macrophages. Using a mouse model of doxorubicin (DOX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea0de7e0aa8bfcbb12d82fc10a1b70f
https://pubmed.ncbi.nlm.nih.gov/31276937
https://pubmed.ncbi.nlm.nih.gov/31276937
Autor:
Jacqueline R Rivas, Sara S Alhakeem, Yang Liu, Joseph M Eckenrode, James P Collard, Yinan Zhang, Khaled A Shaaban, Natarajan Muthusamy, Gerhard C Hildebrandt, Roger A Fleischman, Li Chen, Jon S Thorson, Markos Leggas, Subbarao Bondada
Publikováno v:
The Journal of Immunology. 206:67.19-67.19
T-cell-based immunotherapy revolutionized the treatment of immune suppressive cancers. Blocking T cell inhibitory receptors such as programmed death 1 (PD1) or their ligands (like PD-L1) enhances antitumor T cell responses. However, many cancers empl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::205a8cb90a398723d2b127b95527776c
https://doi.org/10.4049/jimmunol.206.supp.67.19
https://doi.org/10.4049/jimmunol.206.supp.67.19
Autor:
Subbarao Bondada, James P. Collard, Mary Kathryn McKenna, Sunil K. Noothi, Sara S. Alhakeem, Jacqueline R. Rivas, Shelbi Broeking
Publikováno v:
The Journal of Immunology. 204:163.6-163.6
Chronic Lymphocytic Leukemia (CLL), the most prevalent adult leukemia, is characterized by the clonal expansion of CD5+ CD19+ B cells within lymphoid organs and accumulation of quiescent cells in the blood. Eμ-Tcl1 transgenic mice expressing the Tcl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69e32829f23558e743fc782e07e085d1
https://doi.org/10.4049/jimmunol.204.supp.163.6
https://doi.org/10.4049/jimmunol.204.supp.163.6