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Autor:
Sara Rose Dunlop, Ivan Ayala, Callen Spencer, Margaret E Flanagan, Marek-Marsel Mesulam, Tamar Gefen, Changiz Geula
Publikováno v:
Journal of neuropathology and experimental neurology. 81(11)
Basal forebrain cholinergic neurons (BFCN) display accumulation of neurofibrillary tangles and degeneration in Alzheimer disease and are targets of therapeutic intervention. This study determined vulnerability of BFCN to accumulation of TDP-43 in pri