Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sara Restrepo-Vassalli"'
Autor:
Christine Quach, Ying Song, Hongrui Guo, Shun Li, Hadi Maazi, Marshall Fung, Nathaniel Sands, Douglas O’Connell, Sara Restrepo-Vassalli, Billy Chai, Dali Nemecio, Vasu Punj, Omid Akbari, Gregory E. Idos, Shannon M. Mumenthaler, Nancy Wu, Sue Ellen Martin, Ashley Hagiya, James Hicks, Hengmin Cui, Chengyu Liang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
UVRAG is involved in autophagy, which loses its tumour suppressor functions when in its truncated form in cancers. Here, the authors use a mouse model that inducibly express this truncated protein and show impaired autophagy, enhanced inflammation an
Externí odkaz:
https://doaj.org/article/3853dd7ac3f64a118db62600822a7e0c
Autor:
Min Yu, Andrew D. Smith, Frank Attenello, Bodour Salhia, James Hicks, Aditya Bardia, Dejan Juric, Janice Lu, Wange Lu, Michael F. Press, Christopher Pinto, Charlotte S. Walmsley, Diane S. Kang, Grace Lee, Sathish Kumar Ganesan, Kevin J. Liu, Byoung-San Moon, Matthew MacKay, Negeen Izadian, Alan Wang, Sara Restrepo-Vassalli, Lin Li, Oihana Iriondo, Sung Min Han, Teng Teng, Amal Thomas, Remi Klotz
List of upregulated genes in CTC-derived brain metastases compare to other metastases (lung, bone and ovary)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d44a9470a9639e05a7ec089ea9303c2
https://doi.org/10.1158/2159-8290.22535212
https://doi.org/10.1158/2159-8290.22535212
Autor:
Min Yu, Andrew D. Smith, Frank Attenello, Bodour Salhia, James Hicks, Aditya Bardia, Dejan Juric, Janice Lu, Wange Lu, Michael F. Press, Christopher Pinto, Charlotte S. Walmsley, Diane S. Kang, Grace Lee, Sathish Kumar Ganesan, Kevin J. Liu, Byoung-San Moon, Matthew MacKay, Negeen Izadian, Alan Wang, Sara Restrepo-Vassalli, Lin Li, Oihana Iriondo, Sung Min Han, Teng Teng, Amal Thomas, Remi Klotz
Hematogenous metastasis is initiated by a subset of circulating tumor cells (CTC) shed from primary or metastatic tumors into the blood circulation. Thus, CTCs provide a unique patient biopsy resource to decipher the cellular subpopulations that init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7acd707ae05a09bdc19e47539673cc09
https://doi.org/10.1158/2159-8290.c.6547786.v1
https://doi.org/10.1158/2159-8290.c.6547786.v1
Autor:
Min Yu, Andrew D. Smith, Frank Attenello, Bodour Salhia, James Hicks, Aditya Bardia, Dejan Juric, Janice Lu, Wange Lu, Michael F. Press, Christopher Pinto, Charlotte S. Walmsley, Diane S. Kang, Grace Lee, Sathish Kumar Ganesan, Kevin J. Liu, Byoung-San Moon, Matthew MacKay, Negeen Izadian, Alan Wang, Sara Restrepo-Vassalli, Lin Li, Oihana Iriondo, Sung Min Han, Teng Teng, Amal Thomas, Remi Klotz
Includes supplementary tables S1, S2, S5, S6, S7 and S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7b8e91206b2fc820e1ebefbe1d863d
https://doi.org/10.1158/2159-8290.22535200
https://doi.org/10.1158/2159-8290.22535200
Autor:
Min Yu, Andrew D. Smith, Frank Attenello, Bodour Salhia, James Hicks, Aditya Bardia, Dejan Juric, Janice Lu, Wange Lu, Michael F. Press, Christopher Pinto, Charlotte S. Walmsley, Diane S. Kang, Grace Lee, Sathish Kumar Ganesan, Kevin J. Liu, Byoung-San Moon, Matthew MacKay, Negeen Izadian, Alan Wang, Sara Restrepo-Vassalli, Lin Li, Oihana Iriondo, Sung Min Han, Teng Teng, Amal Thomas, Remi Klotz
File includes supplementary figures S1 to S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68175b9edad4f66705f907ad2eb3a57e
https://doi.org/10.1158/2159-8290.22535215.v1
https://doi.org/10.1158/2159-8290.22535215.v1
Autor:
Charlotte S. Walmsley, Negeen Izadian, Bodour Salhia, Sathish Kumar Ganesan, Diane Kang, Min Yu, Michael F. Press, Sung Min Han, Sara Restrepo-Vassalli, Janice Lu, Byoung-San Moon, Alan Wang, Remi Klotz, Grace Lee, Teng Teng, Christopher J. Pinto, Lin Li, Oihana Iriondo, Amal Thomas, Dejan Juric, Aditya Bardia, Matthew MacKay, Kevin Liu, James W. Hicks, Wange Lu, Frank J. Attenello, Andrew D. Smith
Publikováno v:
Cancer Discov
Hematogenous metastasis is initiated by a subset of circulating tumor cells (CTC) shed from primary or metastatic tumors into the blood circulation. Thus, CTCs provide a unique patient biopsy resource to decipher the cellular subpopulations that init
Autor:
Lisa Welter, Liya Xu, Angel E. Dago, Dillon McKinley, Mariam Rodriguez-Lee, Jorge Nieva, James W. Hicks, Rafael Nevarez, Rishvanth K. Prabakar, Carmen Ruiz, Sara Restrepo-Vassalli, Kevin Xu, Anand Kolatkar, Peter Kuhn
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Currently, clinical characterization of metastatic breast cancer is based on tissue samples taken at time of diagnosis. However, tissue biopsies are invasive and tumors are continuously evolving, which indicates the need for minimally invasive longit
Autor:
Mariam Rodriguez-Lee, Joe Larsen, Anders Carlsson, Anna S. Gerdtsson, Carmen Ruiz, Emily J. Greenspan, Sara Restrepo-Vassalli, Kelly Bethel, Peter Kuhn, Jorge Nieva, Liya Xu, Stephanie N. Shishido, Kathryn R. Waitman, Anand Kolatkar, Lisa Welter, James W. Hicks, E. Shelley Hwang
Publikováno v:
J Mol Diagn
Liquid biopsy allows assessment of multiple analytes, providing temporal information with potential for improving understanding of cancer evolution and clinical management of patients. Although liquid biopsies are intensely investigated for predictio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b17d2b106eff52c95e4607ca5d8120a
https://europepmc.org/articles/PMC7103765/
https://europepmc.org/articles/PMC7103765/
Autor:
Hengmin Cui, Vasu Punj, Gregory Idos, Shun Li, Omid Akbari, Douglas O’Connell, Billy Chai, Dali Nemecio, James W. Hicks, Nathaniel Sands, Ying Song, Ashley Hagiya, Hadi Maazi, Nancy Wu, Chengyu Liang, Hongrui Guo, Sue Ellen Martin, Marshall Fung, Sara Restrepo-Vassalli, Christine Quach, Shannon M. Mumenthaler
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Aberrant autophagy is a major risk factor for inflammatory diseases and cancer. However, the genetic basis and underlying mechanisms are less established. UVRAG is a tumor suppressor candidate involved in autophagy, which is truncated in cancers by a
Autor:
Peter Kuhn, Jorge Nieva, Lisa Welter, James W. Hicks, M Rodriguez Lee, Dillon McKinley, Liya Xu, Angel E. Dago, Sara Restrepo-Vassalli, Anand Kolatkar
Publikováno v:
Cancer Research. 79:P3-01
Background: Copy number variation analysis has been shown as a valuable tool to infer clonal evolution of tumor cells. While bulk genomic analysis of FFPE tissue can provide information about the characteristics of a primary tumor or a metastatic nod