Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sara Redenti"'
Autor:
Stephanie Federico, Sara Redenti, Mattia Sturlese, Antonella Ciancetta, Sonja Kachler, Karl-Norbert Klotz, Barbara Cacciari, Stefano Moro, Giampiero Spalluto
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143504 (2015)
A new series of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine (PTP) derivatives has been developed in order to explore their affinity and selectivity profile at the four adenosine receptor subtypes. In particular, the PTP scaffold was conjugated at
Externí odkaz:
https://doaj.org/article/7a562794d0ea427cae270d66fea9e79c
Autor:
Nicola Demitri, Giovanni Bottegoni, Rita De Zorzi, Stephanie Federico, Daniel I. Perez, Paola Storici, Concepción Pérez, Irene Marcovich, Andrea Cavalli, Ana Martínez, Giampiero Spalluto, Paola Bisignano, Maicol Bissaro, Sara Redenti, Teresa De Vita, Stefano Moro
Glycogen synthase kinase 3β (GSK-3β) and casein kinase 1δ (CK-1δ) are emerging targets for the treatment of neuroinflammatory disorders, including Parkinson's disease. An inhibitor able to target these two kinases was developed by docking-based d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159e77e6b1863eb2e2fe2875f32637c8
https://hdl.handle.net/11576/2688418
https://hdl.handle.net/11576/2688418
Autor:
Giampiero Spalluto, Stephanie Federico, Sara Redenti, Antonella Ciancetta, Stefano Moro, Barbara Cacciari, Giorgia Pastorin
Adenosine was defined as a neuromodulator which exerts its action by interaction with specific G-protein coupled receptor termed adenosine receptors. Adenosine receptors are expressed in several tissues and cells of our body and exist as four differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534b743484074b3146329e817737fb85
http://hdl.handle.net/11368/2886221
http://hdl.handle.net/11368/2886221
Autor:
Stefano Moro, Giampiero Spalluto, Stephanie Federico, Karl-Norbert Klotz, Antonella Ciancetta, Giorgia Pastorin, Nicola Porta, Barbara Cacciari, Sara Redenti
The structure–activity relationship of new 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as adenosine receptors (ARs) antagonists has been explored. The introduction of a benzylamino group at C5 with a free amino group at C7 increases th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd85f081a5763aa9b4285a955a01846b
http://hdl.handle.net/11577/3181863
http://hdl.handle.net/11577/3181863
Autor:
Sara Redenti, Stephanie Federico, Mattia Sturlese, Stefano Moro, Antonella Ciancetta, Karl-Norbert Klotz, Giampiero Spalluto, Barbara Cacciari, Sonja Kachler
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 12, p e0143504 (2015)
PLoS ONE, Vol 10, Iss 12, p e0143504 (2015)
A new series of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine (PTP) derivatives has been developed in order to explore their affinity and selectivity profile at the four adenosine receptor subtypes. In particular, the PTP scaffold was conjugated at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030bcd5f6287a583084a0e4ec560554b
https://opus.bibliothek.uni-wuerzburg.de/files/13713/Federico.pdf
https://opus.bibliothek.uni-wuerzburg.de/files/13713/Federico.pdf
Autor:
Stefano Moro, Giorgia Pastorin, Stephanie Federico, Sara Redenti, Antonella Ciancetta, Giampiero Spalluto, Karl-Norbert Klotz, Nicola Porta, Barbara Cacciari
Publikováno v:
Journal of medicinal chemistry. 57(14)
The structure–activity relationship (SAR) of new 5,8-disubstituted-1,2,4-triazolo[1,5-c]pyrimidines as adenosine receptors (ARs) antagonists has been explored. All the synthesized compounds show affinity for the hA2A and hA3 ARs depending on the su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90778deba13ceb87b56f93e476560d4d
https://pubmed.ncbi.nlm.nih.gov/24972108
https://pubmed.ncbi.nlm.nih.gov/24972108