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Akademický článek

The emerging role of irisin in experimentally induced arthritis: a recent update involving HMGB1/MCP1/Chitotriosidase I–mediated necroptosis

Autor: Rowida Raafat Ibrahim, Noha M. Shafik, Rasha Osama El-Esawy, Mervat H. El-Sakaa, Heba M. Arakeeb, Radwa Mahmoud El-Sharaby, Dina Adam Ali, Omnia Safwat El-deeb, Sara Ragab Abd El-Khalik

Publikováno v: Redox Report, Vol 27, Iss 1, Pp 21-31 (2022)

Objectives Necroptosis is a tightly adjusted inflammatory necrotizing cell death signaling pathway that participates in pathogenesis of discrete diseases as rheumatoid arthritis (RA). Irisin is a myokine with immuno-modulatory effect. Evaluation of i

Externí odkaz: https://doaj.org/article/0617f6699d0a4f33ac4f5ae0a353b52a

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Akademický článek

Society for Cardiovascular Magnetic Resonance 2019 Case of the Week series

Publikováno v: Journal of Cardiovascular Magnetic Resonance, Vol 23, Iss 1, Pp 1-29 (2021)

Abstract The Society for Cardiovascular Magnetic Resonance (SCMR) is an international society focused on the research, education, and clinical application of cardiovascular magnetic resonance (CMR). The SCMR web site ( https://www.scmr.org ) hosts a

Externí odkaz: https://doaj.org/article/30df757199bd457a8c7a67f17014aebe

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Akademický článek

Maintained partial protection against Streptococcus pneumoniae despite B‐cell depletion in mice vaccinated with a pneumococcal glycoconjugate vaccine

Autor: Giuseppe Ercoli, Elisa Ramos‐Sevillano, Emma Pearce, Sara Ragab, David Goldblatt, Gisbert Weckbecker, Jeremy S Brown

Publikováno v: Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)

Abstract Objectives Anti‐CD20 monoclonal antibody therapy rapidly depletes > 95% of CD20+ B cells from the circulation. B‐cell depletion is an effective treatment for autoimmune disease and B‐cell malignancies but also increases the risk of res

Externí odkaz: https://doaj.org/article/44361b1c8e4d434ab9c3e34bd97c6843

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Akademický článek

Melatonin as an adjunct to therapeutic hypothermia in a piglet model of neonatal encephalopathy: A translational study

Autor: Nicola J. Robertson, Kathryn Martinello, Ingran Lingam, Adnan Avdic-Belltheus, Christopher Meehan, Daniel Alonso-Alconada, Sara Ragab, Alan Bainbridge, Magdalena Sokolska, Mohamed Tachrount, Benita Middleton, David Price, Mariya Hristova, Xavier Golay, Annamaria Soliani Raschini, Giancarlo Aquino, Nicola Pelizzi, Fabrizio Facchinetti

Publikováno v: Neurobiology of Disease, Vol 121, Iss , Pp 240-251 (2019)

Therapeutic hypothermia is only partially protective for neonatal encephalopathy; there is an urgent need to develop treatments that augment cooling. Our objective was to assess safety, efficacy and pharmacokinetics of 5 and 15 mg/kg/24 h melatonin (

Externí odkaz: https://doaj.org/article/7daf6abf1444477d8d26b24a12891d49

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Akademický článek

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Serial blood cytokine and chemokine mRNA and microRNA over 48 h are insult specific in a piglet model of inflammation-sensitized hypoxia-ischaemia

Autor: Cally J Tann, Henrik Hagberg, Christopher Meehan, Xavier Golay, Nigel Klein, Boris W. Kramer, Adnan Avdic-Belltheus, Tim G. A. M. Wolfs, Ingran Lingam, Kathryn A. Martinello, Pierre Gressens, Melinda Barkhuizen, Sara Ragab, Donald Peebles, Nicola J. Robertson, Bobbi Fleiss, Ilias Tachtsidis

Publikováno v: Pediatric Research, 89(3), 464-475. Nature Publishing Group

BACKGROUND: Exposure to inflammation exacerbates injury in neonatal encephalopathy (NE). We hypothesized that brain biomarker mRNA, cytokine mRNA and microRNA differentiate inflammation (E. coli LPS), hypoxia (Hypoxia), and inflammation-sensitized hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::917ab98a32ec4df54959f57c3651d63b
https://doi.org/10.1038/s41390-020-0986-3

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Evaluation of a Lignin Bio-alkyd Resin for the Selective Determination of Molybdenum in Biological, Pharmaceutical, Fertilizer and Water Samples

Autor: Elhossein Moawed, Sara Ragab, Amira El-Shobaky, Maha El Hagrasy

Publikováno v: Brazilian Journal of Analytical Chemistry. 9

A lignin-based bio-alkyd resin (LA-Resin) was synthesized by the polycondensation reaction of lignin with a mixture of palmitic acid and glycerol. The LA-Resin was characterized using many techniques, including scanning electron microscope, FTIR, X-r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bef91099880c0b804bdad81a2cbd72b0
https://doi.org/10.30744/brjac.2179-3425.ar-122-2021

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Maintained partial protection againstStreptococcus pneumoniaedespite B‐cell depletion in mice vaccinated with a pneumococcal glycoconjugate vaccine

Autor: Giuseppe Ercoli, Elisa Ramos‐Sevillano, Emma Pearce, Sara Ragab, David Goldblatt, Gisbert Weckbecker, Jeremy S Brown

Publikováno v: Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)
Clinical & Translational Immunology

Objectives Anti‐CD20 monoclonal antibody therapy rapidly depletes > 95% of CD20+ B cells from the circulation. B‐cell depletion is an effective treatment for autoimmune disease and B‐cell malignancies but also increases the risk of respiratory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748a11c688a17d30b785f87f4936fa13
https://doi.org/10.1002/cti2.1366

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