Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Sara R Selitsky"'
Autor:
Marta Sanz, Ann Marie K. Weideman, Adam R. Ward, Matthew L. Clohosey, Susana Garcia-Recio, Sara R. Selitsky, Brendan T. Mann, Marie Anne Iannone, Chloe P. Whitworth, Alisha Chitrakar, Carolina Garrido, Jennifer Kirchherr, Alisha R. Coffey, Yi- Hsuan Tsai, Shahryar Samir, Yinyan Xu, Dennis Copertino, Alberto Bosque, Brad R. Jones, Joel S. Parker, Michael G. Hudgens, Nilu Goonetilleke, Natalia Soriano-Sarabia
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Antiretroviral therapy (ART) is not curative due to the existence of cellular reservoirs of latent HIV-1 that persist during therapy. Current research efforts to cure HIV-1 infection include “shock and kill” strategies to disrupt latency using sm
Externí odkaz:
https://doaj.org/article/88374e57932242c08c418283c9d5a0d0
Autor:
Jeffrey S. Damrauer, Markia A. Smith, Vonn Walter, Aatish Thennavan, Lisle E. Mose, Sara R. Selitsky, Katherine A. Hoadley
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Jeffrey Damrauer, Markia Smith et al. used existing datasets from cholangiocarcinoma (CCA) and hepatocellular carcinoma (HCC) to characterize two subsets of HCC distinct from prototypical HCC tumors, based on comprehensive analysis of molecular data.
Externí odkaz:
https://doaj.org/article/c7c5f92165e344fcb51842120c0bf9d1
Autor:
Sara R. Selitsky, David Marron, Daniel Hollern, Lisle E. Mose, Katherine A. Hoadley, Corbin Jones, Joel S. Parker, Dirk P. Dittmer, Charles M. Perou
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Contamination of reagents and cross contamination across samples is a long-recognized issue in molecular biology laboratories. While often innocuous, contamination can lead to inaccurate results. Cantalupo et al., for example, fou
Externí odkaz:
https://doaj.org/article/6cefec523c50451aa5deede07a0e530b
Publikováno v:
European Journal of Cancer. 187:147-160
Autor:
Sara R. Selitsky, Lisle E. Mose, Christof C. Smith, Shengjie Chai, Katherine A. Hoadley, Dirk P. Dittmer, Stergios J. Moschos, Joel S. Parker, Benjamin G. Vincent
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract Background Measures of the adaptive immune response have prognostic and predictive associations in melanoma and other cancer types. Specifically, intratumoral T cell density and function have considerable prognostic and predictive value in s
Externí odkaz:
https://doaj.org/article/b294449e664343b7b7d49abaff4d5f78
Autor:
Moe Matsumoto, Jennifer L Modliszewski, Kotomi Shinozaki, Reona Maezawa, Vincent M Perez, Yuki Ishikawa, Ryosuke Suzuki, Kevin L McKnight, Takahiro Masaki, Asuka Hirai-Yuki, Michinori Kohara, Stanley M Lemon, Sara R Selitsky, Daisuke Yamane
Publikováno v:
Nucleic Acids Research. 51:4451-4466
Interferon regulatory factor 1 (IRF1) is a critical component of cell-intrinsic innate immunity that regulates both constitutive and induced antiviral defenses. Due to its short half-life, IRF1 function is generally considered to be regulated by its
Autor:
Stuart R Jefferys, Samuel D Burgos, Jackson J Peterson, Sara R Selitsky, Anne-Marie W Turner, Lindsey I James, Yi-Hsuan Tsai, Alisha R Coffey, David M Margolis, Joel Parker, Edward P Browne
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009346 (2021)
Transcriptional silencing of HIV in CD4 T cells generates a reservoir of latently infected cells that can reseed infection after interruption of therapy. As such, these cells represent the principal barrier to curing HIV infection, but little is know
Externí odkaz:
https://doaj.org/article/685a177c1c5c40da8c212b641f7fd494
Autor:
Kara R. Eichelberger, Victoria E. Sepúlveda, John Ford, Sara R. Selitsky, Piotr A. Mieczkowski, Joel S. Parker, William E. Goldman
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT Following inhalation, Yersinia pestis rapidly colonizes the lung to establish infection during primary pneumonic plague. Although several adhesins have been identified in Yersinia spp., the factors mediating early Y. pestis adherence in the
Externí odkaz:
https://doaj.org/article/ab34213a353c47eab54d84d386739c36
Autor:
Rutulkumar Patel, Yvonne M. Mowery, Yi Qi, Alex M. Bassil, Matt Holbrook, Eric S. Xu, Cierra S. Hong, Jonathon E. Himes, Nerissa T. Williams, Jeffrey Everitt, Yan Ma, Lixia Luo, Sara R. Selitsky, Jennifer L. Modliszewski, Junheng Gao, Sin-Ho Jung, David G. Kirsch, Cristian T. Badea
Publikováno v:
Mol Cancer Ther
This study aims to investigate whether adding neoadjuvant radiotherapy (RT), anti-programmed cell death protein-1 (PD-1) antibody (anti–PD-1), or RT + anti-PD-1 to surgical resection improves disease-free survival for mice with soft tissue sarcomas
Autor:
Samuel W. Brady, Jasmine A. McQuerry, Yi Qiao, Stephen R. Piccolo, Gajendra Shrestha, David F. Jenkins, Ryan M. Layer, Brent S. Pedersen, Ryan H. Miller, Amanda Esch, Sara R. Selitsky, Joel S. Parker, Layla A. Anderson, Brian K. Dalley, Rachel E. Factor, Chakravarthy B. Reddy, Jonathan P. Boltax, Dean Y. Li, Philip J. Moos, Joe W. Gray, Laura M. Heiser, Saundra S. Buys, Adam L. Cohen, W. Evan Johnson, Aaron R. Quinlan, Gabor Marth, Theresa L. Werner, Andrea H. Bild
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
In metastatic breast cancer, subclonal evolution can drive drug resistance. Here, the authors genetically and transcriptionally follow the evolution of four breast cancers over time and treatment, and suggest a phenotype-targeted treatment strategy t
Externí odkaz:
https://doaj.org/article/f22c7e1eec644bd49c349e24a268484e