Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sara R Abrahams"'
Autor:
Oscar Negrón, Woosuk S Hur, Joni Prasad, David S Paul, Sarah E Rowe, Jay L Degen, Sara R Abrahams, Silvio Antoniak, Brian P Conlon, Wolfgang Bergmeier, Magnus Hӧӧk, Matthew J Flick
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010227 (2022)
The blood-clotting protein fibrin(ogen) plays a critical role in host defense against invading pathogens, particularly against peritoneal infection by the Gram-positive microbe Staphylococcus aureus. Here, we tested the hypothesis that direct binding
Externí odkaz:
https://doaj.org/article/1cdfdde0a1ee486a8eb41935fd614820
Autor:
Nayela N. Chowdhury, Yi Yang, Ananya Dutta, Michelle Luo, Zimu Wei, Sara R. Abrahams, Alexey S. Revenko, Fenil Shah, Lindsey A. Miles, Robert J. Parmer, Bas deLaat, Alisa S. Wolberg, James P. Luyendyk, Melissa L. Fishel, Matthew J. Flick
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 113-135 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal metastatic disease associated with robust activation of the coagulation and fibrinolytic systems. However, the potential contribution of the primary fibrinolytic protease plasminogen to PDAC d
Externí odkaz:
https://doaj.org/article/d7e6f70905c245e1a019d7d8c2f2e56f
Autor:
Yi Yang, Sara R. Abrahams, Matthew J. Flick, Aditi Kothari, Harshi Matada, Keely G. Davey, Alisa S. Wolberg
Publikováno v:
Cancer Research. 81:PO-127
Pancreatic ductal adenocarcinoma (PDAC) is a lethal solid tumor malignancy with a 5-year survival rate of 9%. In both patients and animal models of disease, PDAC is associated with robust coagulation system activity. Intriguingly, in addition to bein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989aef0e181b2dced90a9f885398b3f5
https://doi.org/10.1158/1538-7445.panca21-po-127
https://doi.org/10.1158/1538-7445.panca21-po-127
Autor:
Hartmut Weiler, A. Phillip Owens, Matthew J. Flick, Ashley Goss, Joanne van Ryn, Joseph S. Palumbo, Senad Divanovic, Sara R. Abrahams, Eric S. Mullins, Anna K. Kopec, Nigel Mackman, James P. Luyendyk, Sherry Thornton
Publikováno v:
Journal of Clinical Investigation. 127:3152-3166
Obesity promotes a chronic inflammatory and hypercoagulable state that drives cardiovascular disease, type 2 diabetes, fatty liver disease, and several cancers. Elevated thrombin activity underlies obesity-linked thromboembolic events, but the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2209ba95d0873da77f908287e964e8da
https://doi.org/10.1172/jci92744
https://doi.org/10.1172/jci92744