Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sara Qubisi"'
Autor:
Martin A. Kennedy, Tayaza Fadason, William Schierding, Sophie Farrow, Toni L. Pitcher, Alan J. Davidson, Jo K. Perry, Sara Qubisi, Antony A. Cooper, Oscar E.E. Graham, Tim J. Anderson, Justin M. O'Sullivan
Publikováno v:
Movement Disorders
Background GBA mutations are numerically the most significant genetic risk factor for Parkinson's disease (PD), yet these mutations have low penetrance, suggesting additional mechanisms. Objectives The objective of this study was to determine if the
Autor:
Fazilah Maizatul Abdul Razak, Kostas Kostarelos, Sara Qubisi, Yein Nam, Açelya Yilmazer, Giulio Cossu, Hans Degens, Irene de Lázaro
Publikováno v:
de Lázaro, I, Yilmazer, A, Nam, Y, Qubisi, S, Razak, F M A, Degens, H, Cossu, G & Kostarelos, K 2019, ' Non-viral, Tumor-free Induction of Transient Cell Reprogramming in Mouse Skeletal Muscle to Enhance Tissue Regeneration ', Molecular Therapy, vol. 27, no. 1, pp. 59-75 . https://doi.org/10.1016/j.ymthe.2018.10.014
© 2018 The American Society of Gene and Cell Therapy. Overexpression of Oct3/4, Klf4, Sox2, and c-Myc (OKSM) transcription factors can de-differentiate adult cells in vivo. While sustained OKSM expression triggers tumorigenesis through uncontrolled