Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sara Priego Moreno"'
Autor:
Sara Priego Moreno, Javier Miralles Fusté, Melanie Kaiser, Julia Su Zhou Li, Joe Nassour, Candy Haggblom, Eros Lazzerini Denchi, Jan Karlseder
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106405- (2023)
Summary: The appropriate regulation of telomere length homeostasis is crucial for the maintenance of genome integrity. The telomere-binding protein TZAP has been suggested to regulate telomere length by promoting t-circle and c-circle excisions throu
Externí odkaz:
https://doaj.org/article/8bf0cd1dfa674cda89cdbca6828530fd
Autor:
Celina Y. Jones, Christopher L. Williams, Sara Priego Moreno, Danna K. Morris, Chiara Mondello, Jan Karlseder, Alison A. Bertuch
Publikováno v:
Journal of Biological Chemistry. 299:104665
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d49219a7294fa245537cc65555f0b392
https://doi.org/10.1016/j.jbc.2023.104665
https://doi.org/10.1016/j.jbc.2023.104665
Autor:
Sara Priego Moreno, Agnieszka Gambus
Publikováno v:
Biochemical Society Transactions
DNA replication is a complex process that needs to be executed accurately before cell division in order to maintain genome integrity. DNA replication is divided into three main stages: initiation, elongation and termination. One of the key events dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8636d5a9df01a36ef1ccdd96539f846e
https://pubmed.ncbi.nlm.nih.gov/32490508
https://pubmed.ncbi.nlm.nih.gov/32490508
Autor:
Remi, Sonneville, Sara Priego, Moreno, Axel, Knebel, Clare, Johnson, C James, Hastie, Anton, Gartner, Agnieszka, Gambus, Karim, Labib
Publikováno v:
Nature cell biology
Cell Death and Differentiation
Cell Death and Differentiation
Replisome disassembly is the final step of DNA replication in eukaryotes, involving the ubiquitylation and CDC48-dependent dissolution of the CMG helicase (Cdc45-MCM-GINS). Using Caenorhabditis elegans early embryos and Xenopus egg extracts, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e494b73582028e99401cdbd7e07c2bb5
http://europepmc.org/articles/PMC5410169
http://europepmc.org/articles/PMC5410169
Autor:
Sara Priego Moreno
Publikováno v:
DNA Repair and Replication ISBN: 9780429464744
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2964739e6b36dd0b7602e5c791559fb8
https://doi.org/10.1201/9780429464744-2
https://doi.org/10.1201/9780429464744-2
Recent years have brought a breakthrough in our understanding of the process of eukaryotic DNA replication termination. We have shown that the process of replication machinery (replisome) disassembly at the termination of DNA replication forks in S-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daabc04bba6cf0f2e089de6d68a3b4db
Autor:
Agnieszka Gambus, Sara Priego Moreno
Publikováno v:
Genes
Genes, Vol 6, Iss 3, Pp 451-468 (2015)
Genes, Vol 6, Iss 3, Pp 451-468 (2015)
Posttranslational modification of proteins by means of attachment of a small globular protein ubiquitin (i.e., ubiquitylation) represents one of the most abundant and versatile mechanisms of protein regulation employed by eukaryotic cells. Ubiquityla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523120bcce07e32a3e8c5cb357a1e96b
http://europepmc.org/articles/PMC4584310
http://europepmc.org/articles/PMC4584310
Publikováno v:
Nucleus
To ensure duplication of the entire genome, eukaryotic DNA replication initiates from thousands of replication origins. The replication forks move through the chromatin until they encounter forks from neighboring origins. During replication fork term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8f3ed60bb224024c9f0d5fb11c2cb8
https://doi.org/10.1080/19491034.2015.1035843
https://doi.org/10.1080/19491034.2015.1035843
Publikováno v:
Science. 346:477-481
How to stop after copying the genome Replication is highly regulated: Failure to copy any part of the genome or copying parts of it more than once can cause genome instability with potentially disastrous consequences. Maric et al. and Priego Moreno e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5a1cfb43b37db84d4a7fe7b468df484
https://doi.org/10.1126/science.1253585
https://doi.org/10.1126/science.1253585
Autor:
Divyasree Poovathumkadavil, Rebecca M. Jones, Sara Priego Moreno, Shaun Scaramuzza, Agnieszka Gambus
Publikováno v:
Life Science Alliance
Analysis of the mitotic replisome disassembly pathway in X. laevis egg extract shows that any replisomes retained on chromatin past S-phase are unloaded through formation of K6- and K63-linked ubiquitin chains on Mcm7 by TRAIP ubiquitin ligase and p9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e56976b4986e600bc578db74c69f72
https://doi.org/10.26508/lsa.201900390
https://doi.org/10.26508/lsa.201900390