Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sara Petković"'
Autor:
Silvia Nitschke, Mitchell A Sullivan, Sharmistha Mitra, Charlotte R Marchioni, Jennifer P Y Lee, Brandon H Smith, Saija Ahonen, Jun Wu, Erin E Chown, Peixiang Wang, Sara Petković, Xiaochu Zhao, Laura F DiGiovanni, Ami M Perri, Lori Israelian, Tamar R Grossman, Holly Kordasiewicz, Francisco Vilaplana, Kazuhiro Iwai, Felix Nitschke, Berge A Minassian
Publikováno v:
Brain
Longer glucan chains tend to precipitate. Glycogen, by far the largest mammalian glucan and the largest molecule in the cytosol with up to 55 000 glucoses, does not, due to a highly regularly branched spherical structure that allows it to be perfused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59293c4929b2bbb5d47f012bf06d7c1
https://doi.org/10.1093/brain/awac017
https://doi.org/10.1093/brain/awac017
Sensitive quantification of α-glucans in mouse tissues, cell cultures, and human cerebrospinal fluid
Publikováno v:
J Biol Chem
The soluble α-polyglucan glycogen is a central metabolite enabling transient glucose storage to suit cellular energy needs. Glycogen storage diseases (GSDs) comprise over 15 entities caused by generalized or tissue-specific defects in enzymes of gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d53d94f0a3823eb1fe585caf8bc01a
https://pubmed.ncbi.nlm.nih.gov/32817315
https://pubmed.ncbi.nlm.nih.gov/32817315
Autor:
Saija Ahonen, Sara Petković, Silvia Nitschke, Ami M. Perri, Berge A. Minassian, Erin E. Chown, Xiaochu Zhao, Dikran R Guisso, Shoghig Gabrielian, Felix Nitschke, Peixiang Wang
Publikováno v:
The Journal of Biological Chemistry
Malstructured glycogen accumulates over time in Lafora disease (LD) and precipitates into Lafora bodies (LBs), leading to neurodegeneration and intractable fatal epilepsy. Constitutive reduction of glycogen synthase-1 (GYS1) activity prevents murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da255d8aba5c189be5ac74a2ddc77d7d
https://doi.org/10.1074/jbc.ra120.015773
https://doi.org/10.1074/jbc.ra120.015773