Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sara Petek"'
Autor:
Cene Skubic, Hana Trček, Petra Nassib, Tinkara Kreft, Andrew Walakira, Katka Pohar, Sara Petek, Tadeja Režen, Alojz Ihan, Damjana Rozman
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110651- (2024)
Summary: Sterols from cholesterol synthesis are crucial for cholesterol production, but also have individual roles difficult to assess in vivo due to essentiality of cholesterol. We developed HepG2 cell models with knockouts (KOs) for three enzymes o
Externí odkaz:
https://doaj.org/article/ebd81049d2e34d6089edf8afcf668a26
Autor:
Cene Skubic, Hana Trček, Petra Nassib, Andrew Walakira, Katka Pohar, Sara Petek, Tadeja Režen, Alojz Ihan, Damjana Rozman
Sterol intermediates of cholesterol synthesis are largely dedicated to cholesterol. Here we assess how they influence downstream gene regulatory pathways by developing knockouts (KOs) for consecutive enzymes of cholesterol synthesis. Depletion ofCYP5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d130ec594abc6991d99843d4bc498ef
https://doi.org/10.1101/2023.05.19.538399
https://doi.org/10.1101/2023.05.19.538399
