Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sara P. Rao"'
Autor:
Darlene R. Giracello, Blake A. Rowe, Nicholas D. P. Cosford, Mark A. Varney, Deborah F. Chapman, Margaret J. Bradbury, Jeffery J. Anderson, Lida R. Tehrani, Greg Holtz, Sara P. Rao
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 303:1044-1051
The binding of [3H]methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (methoxymethyl-MTEP), a potent and selective antagonist for metabotropic glutamate (mGlu)5 receptors, was characterized in rat brain both in vitro and in vivo. Nonspecifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02261e288431280fa923c3e0993cf6e7
https://doi.org/10.1124/jpet.102.040618
https://doi.org/10.1124/jpet.102.040618
Autor:
Lorrie P. Daggett, Peter J. Flor, J A Kerner, Rainer Kuhn, Anne B. Young, Aida I. Sacaan, David G. Standaert, F.-F. Lin, Gonul Velicelebi, C. Jachec, Mark A. Varney, Sara P. Rao
Publikováno v:
Neuropharmacology. 36:917-931
We isolated and characterized a cDNA encoding the human metabotropic glutamate receptor subtype 1b (hmGluR1b). In situ hybridization studies in human brain regions revealed a higher distribution of mGluR1 mRNA in the dentate gyrus of the hippocampus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afcfb231ef05175c7d3420cc0542c60
https://doi.org/10.1016/s0028-3908(97)00078-6
https://doi.org/10.1016/s0028-3908(97)00078-6
Autor:
Mark A. Varney, Blake A. Rowe, Jean-Michel Vernier, Gretchen Bain, C. Jachec, Linda J. Bristow, Anthony B. Pinkerton, Lorrie P. Daggett, Sylvia Morales, Hervé Schaffhauser, Laura E. Chavez-Noriega, Sara P. Rao, Ruoyuan Yin
Publikováno v:
Molecular pharmacology. 64(4)
In the present study, we describe the characterization of a positive allosteric modulator at metabotropic glutamate subtype 2 receptors (mGluR2). N-(4-(2-Methoxyphenoxy)-phenyl-N-(2,2,2-trifluoroethylsulfonyl)-pyrid-3-ylmethylamine (LY487379) is a se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5524c5ffa027de7649441d93d4f3a2
https://pubmed.ncbi.nlm.nih.gov/14500736
https://pubmed.ncbi.nlm.nih.gov/14500736
Autor:
Natacha Stoehr, Michel Biollaz, Mark A. Varney, Fabrizio Gasparini, Micheline Heinrich, Peter J. Flor, Gonul Velicelebi, Rainer Kuhn, Sara P. Rao, Edwin C. Johnson, Ivo Vranesic, Roland Heckendorn, Kurt Lingenhöhl, Aida I. Sacaan, Emily M. Santori, Stephen D. Hess, Hans Allgeier, Stephan Urwyler
Publikováno v:
Neuropharmacology. 38(10)
In the present paper we describe 2-methyl-6-(phenylethynyl)-pyridine (MPEP) as a potent, selective and systemically active antagonist for the metabotropic glutamate receptor subtype 5 (mGlu5). At the human mGlu5a receptor expressed in recombinant cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea32ab65e402da78f8c42a756c75519a
https://pubmed.ncbi.nlm.nih.gov/10530811
https://pubmed.ncbi.nlm.nih.gov/10530811
Autor:
Steven B. Ellis, C.M. Testa, Aida I. Sacaan, Lorrie P. Daggett, Arturo Urrutia, Gonul Velicelebi, C. Liaw, Jörg Dreessen, Mark A. Varney, Anne B. Young, C. Jachec, Sara P. Rao, Stephen D. Hess, G.B. Landwehrmeyer, Edwin C. Johnson, Thomas Knöpfel, M. Akong
Publikováno v:
Neuropharmacology. 34(8)
We have isolated and characterized overlapping cDNAs that encode two isoforms of the human metabotropic glutamate receptor subtype 5 (hmGluR5). The deduced amino acid sequences of human and rat mGluR5a are 94.5% identical. However, a region in the pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d175c39ce9e2a5ba453e340abb3e76
https://pubmed.ncbi.nlm.nih.gov/8532169
https://pubmed.ncbi.nlm.nih.gov/8532169