Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sara Orgad"'
Publikováno v:
Journal of Immunotherapy. 33:146-154
The tumor suppressor gene p53 is mutated in more than half of human tumors. One important characteristic of p53 mutants is their accumulation in the nucleus of cancer cells. Thus, reactivation of mutant p53 proteins may trigger massive apoptosis in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581d9835597201437875faac0fbd13d0
https://doi.org/10.1097/cji.0b013e3181be14dc
https://doi.org/10.1097/cji.0b013e3181be14dc
Publikováno v:
Scopus-Elsevier
The courtless (col) mutation disrupts early steps of courtship behavior in Drosophila males, as well as the development of their sperm. Most of the homozygous col/col males (78%) do not court at all. Only 5% perform the entire ritual and copulate, ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2cde2cadd400549d00797e4b3a44773
https://doi.org/10.1093/genetics/155.3.1267
https://doi.org/10.1093/genetics/155.3.1267
Publikováno v:
FEBS letters. 579(25)
Here, we describe the biological activity of ME1, a mouse single chain Fv fragment (scFv) against the common epitope of mutant p53, which is efficiently expressed in mammalian cells. We found that in vivo interaction of the conformational p53 mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab0a7c93cc094214773e3d16498eb2d
https://pubmed.ncbi.nlm.nih.gov/16213502
https://pubmed.ncbi.nlm.nih.gov/16213502
Publikováno v:
Invertebrate neuroscience : IN. 3(2-3)
We describe six recessive autosomal male sterile mutations in Drosophila, generated by mobilization of single P-elements, exhibiting abnormal male courtship behavior. Detailed analysis of courtship behavior elicited by virgin wild type females indica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81914464de65a8d2fcc09f25769f6a7
https://pubmed.ncbi.nlm.nih.gov/9783442
https://pubmed.ncbi.nlm.nih.gov/9783442
Autor:
Yael Nevo-Caspi, Shiri Freilich, Sara Orgad, Daniel A. Chamovitz, Daniel L. Segal, Efrat Oron, Ya'ara Kapp
Publikováno v:
Current Biology. 9:1187-S4
The COP9 signalosome (originally described as the COP9 complex) is an essential multi-subunit repressor of light-regulated development in plants [1] [2]. It has also been identified in mammals, though its role remains obscure [3] [4] [5]. This comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00eb0b6cff31283f2fa2f88134f80900
https://doi.org/10.1016/s0960-9822(00)80023-8
https://doi.org/10.1016/s0960-9822(00)80023-8
Publikováno v:
European Journal of Neuroscience. 1:367-373
The tetanic (tta; X.-52.6) mutation has been isolated on the basis of its sensitivity to extradoses of the normal Shaker gene complex (ShC) where the K+ channel la is encoded. The mutant shows up to threefold elevation of the membrane bound protein p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3eb20672f43c405b979833e0cc15bba
https://doi.org/10.1111/j.1460-9568.1989.tb00801.x
https://doi.org/10.1111/j.1460-9568.1989.tb00801.x
Publikováno v:
FEBS Letters. (1-2):44-48
cDNA coding for protein phosphatase 2A (PP2A) has been isolated from Drosophila head and eye imaginal disc libraries. Drosophila PP2A mRNA is expressed throughout development, but is most abundant in the early embryo. The cDNA hybridises to a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b07cbd3af184ea087172e24b93644e
Publikováno v:
European journal of biochemistry. 164(1)
Protein phosphatases-1, 2A and 2B have been identified in membrane and soluble fractions of Drosophila melanogaster heads. Similarities between Drosophila and mammalian protein phosphatase-1 included specificity for the beta subunit of phosphorylase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac38ff6a32d1f4d2a4fcf32093dd02e
https://pubmed.ncbi.nlm.nih.gov/3030753
https://pubmed.ncbi.nlm.nih.gov/3030753
Autor:
Michal Shoresh, Shirly Abiri, Daniel L. Segal, Ruth Werczberger, Sara Orgad, Dana Gelbaum, Orit Shmueli
Publikováno v:
Scopus-Elsevier
LIM domains function as bridging modules between different members of multiprotein complexes. We report the cloning of a LIM-containing gene from Drosophila, termed Dlmo, which is highly homologous to the vertebrate LIM-only (LMO) genes. The 3′ unt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef04441ff3723ec3b3ebdf0dcff4eaf
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031719962&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031719962&partnerID=MN8TOARS
Publikováno v:
Scopus-Elsevier
A mutation in the malvolio (mvl) gene affects taste behavior in Drosophila melanogaster. The malvolio gene encodes a protein (MVL) that exhibits homology to the mammalian natural resistance-associated macrophage proteins. It is also homologous to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2449ed96de9c30811a96a4a5c591c3c
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031933728&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031933728&partnerID=MN8TOARS