Early prolonged neutrophil activation in critically ill patients with sepsis

Autor: Sanna Törnblom, Sara Nisula, Suvi T Vaara, Meri Poukkanen, Sture Andersson, Ville Pettilä, Eero Pesonen

Publikováno v: Innate Immunity, Vol 27 (2021)

We hypothesised that plasma concentrations of biomarkers of neutrophil activation and pro-inflammatory cytokines differ according to the phase of rapidly evolving sepsis. In an observational study, we measured heparin-binding protein (HBP), myelopero

Externí odkaz: https://doaj.org/article/6b04ffbcf6fe4954b18759ab60f12e60

Urine NGAL as a biomarker for septic AKI: a critical appraisal of clinical utility-data from the observational FINNAKI study

Autor: Sanna, Törnblom, Sara, Nisula, Liisa, Petäjä, Suvi T, Vaara, Mikko, Haapio, Eero, Pesonen, Ville, Pettilä, Maria, Skinnar

Publikováno v: Annals of Intensive Care
Annals of Intensive Care, Vol 10, Iss 1, Pp 1-10 (2020)

Background Neutrophil gelatinase-associated lipocalin (NGAL) is released from kidney tubular cells under stress as well as from neutrophils during inflammation. It has been suggested as a biomarker for acute kidney injury (AKI) in critically ill pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37cead7167578876b6ff0af0212360e
https://pubmed.ncbi.nlm.nih.gov/32347418

Association of oliguria with the development of acute kidney injury in the critically ill

Autor: Suvi T. Vaara, Ilkka Parviainen, Ville Pettilä, Sara Nisula, Outi Inkinen, Ari Uusaro, Raili Laru-Sompa, Anni Pulkkinen, Minna Saarelainen, Mikko Reilama, Sinikka Tolmunen, Ulla Rantalainen, Markku Suvela, Katrine Pesola, Pekka Saastamoinen, Kirsi-Maija Kaukonen, Anna-Maija Korhonen, Suvi Vaara, Raili Suojaranta-Ylinen, Leena Mildh, Mikko Haapio, Laura Nurminen, Sari Sutinen, Leena Pettilä, Helinä Laitinen, Heidi Syrjä, Kirsi Henttonen, Elina Lappi, Tero Varpula, Päivi Porkka, Mirka Sivula, Mira Rahkonen, Anne Tsurkka, Taina Nieminen, Ari Alaspää, Ville Salanto, Hanna Juntunen, Esko Ruokonen, Stepani Bendel, Niina Rissanen, Maarit Lång, Sari Rahikainen, Saija Rissanen, Merja Ahonen, Elina Halonen, Meri Poukkanen, Esa Lintula, Jorma Heikkinen, Timo Lavander, Kirsi Heinonen, Tadeusz Kaminski, Fiia Gäddnäs, Tuija Kuusela, Sari Karlsson, Matti Reinikainen, Tero Surakka, Helena Jyrkönen, Tanja Eiserbeck, Tero Ala-Kokko, Jouko Laurila, Vesa Lund, Päivi Tuominen, Pauliina Perkola, Riikka Tuominen, Marika Hietaranta, Seppo Hovilehto, Anne Kirsi, Pekka Tiainen, Tuija Myllärinen, Pirjo Leino, Anne Kuitunen, Jyrki Tenhu-nen, Ilona Leppänen, Markus Levoranta, Sanna Hoppu, Jukka Sauranen, Atte Kukkurainen, Samuli Kortelainen, Niina Koivuviita, Jutta Kotamäki, Simo-Pekka Koivisto, Raku Hautamäki, Maria Skinnar

Publikováno v: Kidney International. 89(1):200-208

Urine output (UO) criterion may increase the sensitivity of the definition of acute kidney injury (AKI). We determined whether the empirically derived definition for oliguria (0.5 ml/kg/h) is independently associated with adverse outcome. Data analys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64801833f1e7620ffdbaed0f3cc78283
https://doi.org/10.1038/ki.2015.269

Acute Kidney Injury After Cardiac Surgery by Complete KDIGO Criteria Predicts Increased Mortality

Autor: Markku Salmenperä, Sara Nisula, Anna-Maija Korhonen, Ville Pettilä, Suvi T. Vaara, Raili Suojaranta-Ylinen, Leena Mildh, Kirsi-Maija Kaukonen, Liisa Petäjä, Sasu Liuhanen

Objectives: Acute kidney injury (AKI) occurs frequently after cardiac surgery and is associated with increased mortality. The Kidney Disease: Improving Global Outcomes (KDIGO) criteria for diagnosing AKI include creatinine and urine output values. Ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2245662e30df4cac9317e0b7c74248ad
http://hdl.handle.net/10138/297842

Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study

Autor: Anne Kuitunen, Raili Suojaranta-Ylinen, Jyrki Tenhunen, Tero Ala-Kokko, Matti Reinikainen, Anna-Maija Korhonen, Outi Inkinen, Ville Pettilä, Sara Nisula, Mikko Haapio, Sari Karlsson, Ilkka Parviainen, Jouko J Laurila, Suvi T. Vaara, Esko Ruokonen, Meri Poukkanen, Kirsi-Maija Kaukonen

Publikováno v: Intensive Care Medicine. 39:420-428

Purpose We aimed to determine the incidence, risk factors and outcome of acute kidney injury (AKI) in Finnish ICUs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fac319bcae454f3bda3a966a0eff8b27
https://doi.org/10.1007/s00134-012-2796-5