Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sara N. Kassel"'
Autor:
Victoria H. Ng, Zachary Spencer, Leif R. Neitzel, Anmada Nayak, Matthew A. Loberg, Chen Shen, Sara N. Kassel, Heather K. Kroh, Zhenyi An, Christin C. Anthony, Jamal M. Bryant, Amanda Lawson, Lily Goldsmith, Hassina Benchabane, Amanda G. Hansen, Jingjing Li, Starina D’Souza, Andres M. Lebensohn, Rajat Rohatgi, William A. Weiss, Vivian L. Weiss, Charles Williams, Charles C. Hong, David J. Robbins, Yashi Ahmed, Ethan Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The relative abundance of Wnt receptors plays a crucial role in controlling Wnt signaling in tissue homeostasis and human disease. While the ubiquitin ligases that ubiquitylate Wnt receptors are well-characterized, the deubiquitylase that re
Externí odkaz:
https://doaj.org/article/ef64ae66e0614f03b079cfeb3260d710
The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6
Autor:
Zachary T. Spencer, Victoria H. Ng, Hassina Benchabane, Ghalia Saad Siddiqui, Deepesh Duwadi, Ben Maines, Jamal M. Bryant, Anna Schwarzkopf, Kai Yuan, Sara N. Kassel, Anant Mishra, Ashley Pimentel, Andres M. Lebensohn, Rajat Rohatgi, Scott A. Gerber, David J. Robbins, Ethan Lee, Yashi Ahmed
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The control of Wnt receptor abundance is critical for animal development and to prevent tumorigenesis, but the mechanisms that mediate receptor stabilization remain uncertain. We demonstrate that stabilization of the essential Wingless/Wnt r
Externí odkaz:
https://doaj.org/article/7643daf365c140e9a3c0f62a66350abb
Autor:
Evan M. Hess, Sara N. Kassel, Gregory Simandl, Nicholas Raddatz, Brian Maunze, Matthew M. Hurley, Michael Grzybowski, Jason Klotz, Aron Geurts, Qing-Song Liu, SuJean Choi, Robert C. Twining, David A. Baker
Publikováno v:
The Journal of Neuroscience. 43:2349-2361
The importance of neuronal glutamate to synaptic transmission throughout the brain illustrates the immense therapeutic potential and safety risks of targeting this system. Astrocytes also release glutamate, the clinical relevance of which is unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0f13b5b3165b41660ba3aa7a247cb6
https://doi.org/10.1523/jneurosci.1525-22.2023
https://doi.org/10.1523/jneurosci.1525-22.2023