Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Sara N Smith"'
Autor:
Laura A Mike, Andrew J Stark, Valerie S Forsyth, Jay Vornhagen, Sara N Smith, Michael A Bachman, Harry L T Mobley
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009376 (2021)
Hypervirulent K. pneumoniae (hvKp) is a distinct pathotype that causes invasive community-acquired infections in healthy individuals. Hypermucoviscosity (hmv) is a major phenotype associated with hvKp characterized by copious capsule production and p
Externí odkaz:
https://doaj.org/article/9c527e2000c44b9c93b2cdaf8183b5c6
Autor:
Chelsie E Armbruster, Valerie S Forsyth, Alexandra O Johnson, Sara N Smith, Ashley N White, Aimee L Brauer, Brian S Learman, Lili Zhao, Weisheng Wu, Mark T Anderson, Michael A Bachman, Harry L T Mobley
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007653 (2019)
The Gram-negative bacterium Proteus mirabilis is a common cause of catheter-associated urinary tract infections (CAUTI), which can progress to secondary bacteremia. While numerous studies have investigated experimental infection with P. mirabilis in
Externí odkaz:
https://doaj.org/article/3b1cfff69ee54e98a7399e8f7df5af4c
Autor:
Chelsie E Armbruster, Valerie Forsyth-DeOrnellas, Alexandra O Johnson, Sara N Smith, Lili Zhao, Weisheng Wu, Harry L T Mobley
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006434 (2017)
The Gram-negative bacterium Proteus mirabilis is a leading cause of catheter-associated urinary tract infections (CAUTIs), which are often polymicrobial. Numerous prior studies have uncovered virulence factors for P. mirabilis pathogenicity in a muri
Externí odkaz:
https://doaj.org/article/b07668fdcd7542e18be917316ffaf268
Autor:
Travis J Wiles, J Paul Norton, Sara N Smith, Adam J Lewis, Harry L T Mobley, Sherwood R Casjens, Matthew A Mulvey
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2, p e1003175 (2013)
In bacteria, laterally acquired genes are often concentrated within chromosomal regions known as genomic islands. Using a recently developed zebrafish infection model, we set out to identify unique factors encoded within genomic islands that contribu
Externí odkaz:
https://doaj.org/article/d49905ca984a489ea54e4ab41c8b8c45
Autor:
Sargurunathan Subashchandrabose, Sara N Smith, Rachel R Spurbeck, Monica M Kole, Harry L T Mobley
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003788 (2013)
Uropathogenic Escherichia coli (UPEC) is a leading etiological agent of bacteremia in humans. Virulence mechanisms of UPEC in the context of urinary tract infections have been subjected to extensive research. However, understanding of the fitness mec
Externí odkaz:
https://doaj.org/article/a37e845282564aba853adf89c3f73ad8
Publikováno v:
PLoS Pathogens, Vol 5, Iss 9, p e1000586 (2009)
Uncomplicated infections of the urinary tract, caused by uropathogenic Escherichia coli, are among the most common diseases requiring medical intervention. A preventive vaccine to reduce the morbidity and fiscal burden these infections have upon the
Externí odkaz:
https://doaj.org/article/9d4e8f5e54c5494a96ead3a5f5249962
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000448 (2009)
Microbial pathogenesis studies traditionally encompass dissection of virulence properties such as the bacterium's ability to elaborate toxins, adhere to and invade host cells, cause tissue damage, or otherwise disrupt normal host immune and cellular
Externí odkaz:
https://doaj.org/article/3a2558761cac4e3d9f7b6d93b791122e
Bacteremia, a systemic infection associated with severe clinical outcomes, is often caused by Gram-negative facultative anaerobes. ArcAB, a two-component regulatory system that represses aerobic respiration, is a key mediator of metabolic adaptation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2da3d38c9398007cd58d08bcdabbc372
https://doi.org/10.1101/2023.04.18.537286
https://doi.org/10.1101/2023.04.18.537286
Autor:
Caitlyn L. Holmes, Alexis E. Wilcox, Valerie Forsyth, Sara N. Smith, Bridget S. Moricz, Lavinia V. Unverdorben, Sophia Mason, Weisheng Wu, Lili Zhao, Harry L.T. Mobley, Michael A. Bachman
Gram-negative bacteremia is a major cause of global morbidity involving three phases of pathogenesis: initial site infection, dissemination, and survival in the blood and filtering organs.Klebsiella pneumoniaeis a leading cause of bacteremia and pneu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc723ee519b03c7c99766f1c5a4e095e
https://doi.org/10.1101/2023.02.23.529827
https://doi.org/10.1101/2023.02.23.529827
Autor:
Sophia Mason, Jay Vornhagen, Sara N. Smith, Laura A. Mike, Harry L. T. Mobley, Michael A. Bachman
Publikováno v:
Infection and Immunity. 91
Healthcare-acquired infections are a leading cause of disease in patients that are hospitalized or in long-term-care facilities. Klebsiella pneumoniae (Kp) is a leading cause of bacteremia, pneumonia, and urinary tract infections in these settings. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69d12659165037fc1bd91661b8a02e20
https://doi.org/10.1128/iai.00559-22
https://doi.org/10.1128/iai.00559-22