Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sara Moein"'
Autor:
Julie P. Merchant, Kuixi Zhu, Marc Y. R. Henrion, Syed S. A. Zaidi, Branden Lau, Sara Moein, Melissa L. Alamprese, Richard V. Pearse, David A. Bennett, Nilüfer Ertekin-Taner, Tracy L. Young-Pearse, Rui Chang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
Abstract Despite decades of genetic studies on late-onset Alzheimer’s disease, the underlying molecular mechanisms remain unclear. To better comprehend its complex etiology, we use an integrative approach to build robust predictive (causal) network
Externí odkaz:
https://doaj.org/article/59af61a1276a4d158efbd9462249793a
Autor:
Ivan Carcamo-Orive, Marc Y R Henrion, Kuixi Zhu, Noam D Beckmann, Paige Cundiff, Sara Moein, Zenan Zhang, Melissa Alamprese, Sunita L D'Souza, Martin Wabitsch, Eric E Schadt, Thomas Quertermous, Joshua W Knowles, Rui Chang
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 12, p e1008491 (2020)
Insulin resistance (IR) precedes the development of type 2 diabetes (T2D) and increases cardiovascular disease risk. Although genome wide association studies (GWAS) have uncovered new loci associated with T2D, their contribution to explain the mechan
Externí odkaz:
https://doaj.org/article/c45804cefb884fd3b6173fff99721b01
Autor:
Sara Moein, Zahra Beheshti
Publikováno v:
Journal of Intelligent Procedures in Electrical Technology, Vol 2, Iss 5, Pp 43-48 (2011)
Nowadays, Kalman filter has been wildly used for solving the problem of real world. Kalman filter is a recursive filter that estimates the state of a linear dynamic system from a series of noisy measurements. One of the applications of Kalman filter
Externí odkaz:
https://doaj.org/article/a9a018237ca449d9be525809ddf82013
Autor:
Julie P. Merchant, Kuixi Zhu, Marc Y.R. Henrion, Syed S.A. Zaidi, Lau Branden, Sara Moein, Melissa L. Alamprese, Richard V. Pearse, David A. Bennett, Nilüfer Ertekin-Taner, Tracy L. Young-Pearse, Rui Chang
SummaryDespite decades of genetic studies on late onset Alzheimer’s disease (LOAD), the molecular mechanisms of Alzheimer’s disease (AD) remain unclear. Furthermore, different cell types in the central nervous system (CNS) play distinct roles in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11a87d44e5deedcfff4abfe4cb1558cb
https://doi.org/10.1101/2022.10.19.512949
https://doi.org/10.1101/2022.10.19.512949
Autor:
Kuixi Zhu, Qianying He, Sheng-Feng Tsai, Dinusha Maheepala Mudalige, Marc Y.R. Henrion, Syed S.A. Zaidi, Lau Branden, Andrew Tang, Mika P. Cadiz, Rachel Hodos-Nkhereanye, Sara Moein, Melissa L. Alamprese, David A. Bennett, Philip L. De Jager, John D. Frye, Nilu□fer Ertekin-Taner, Yu-Min Kuo, Patrick T. Ronaldson, Rui Chang
SummaryMicroglia, the innate immune cells of the brain, are essential determinants of late-onset Alzheimer’s Disease (LOAD) neuropathology. Here, we developed an integrative computational systems biology approach to construct causal network models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4b6baba1fad4b7c1351b1701d149bb7
https://doi.org/10.1101/2022.10.19.512953
https://doi.org/10.1101/2022.10.19.512953
Autor:
Chhiring Lama, Shira Rosenberg, Andrea Kubas-Meyer, X. Amy Xie, Sara Moein, Neelang Parghi, Mansi Totwani, Mirca S. Saurty-Seerunghen, Mohamed Omar, Alicia Dillard, Nathaniel D. Omans, Neville Dusaj, Paulina Chamely, Eleni Mimitou, Peter Smibert, Heidi E. Kosiorek, Amylou C. Dueck, Rona Weinberg, Ronan Chaligne, Luigi Marchionni, Sanjay Patel, Paul Simonson, Dan A. Landau, Ronald Hoffman, Anna S. Nam
Inflammatory cytokines perturb hematopoietic stem cell (HSC) homeostasis and modulate the fitness of neoplastic HSC clones in mouse models. However, the study of cytokines in human hematopoiesis is challenging due to the concerted activities of multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ac602f6bc3bc5e3adab43f35c4ca192
https://doi.org/10.1101/2022.09.28.509751
https://doi.org/10.1101/2022.09.28.509751
Publikováno v:
Optics Continuum. 2:769
Point spread function engineering uses specially designed phase plates placed at the exit pupil of an imaging system to reduce defocusing sensitivity. A custom phase plate is typically required for each system to enable extended depth of field imagin
Publikováno v:
Intelligent Automation & Soft Computing. 27:723-735
Autor:
Rui, Chang, Eugenia, Trushina, Kuixi, Zhu, Syed Shujaat Ali, Zaidi, Branden M, Lau, Alexandra, Kueider-Paisley, Sara, Moein, Qianying, He, Melissa L, Alamprese, Barbora, Vagnerova, Andrew, Tang, Ramachandran, Vijayan, Yanyun, Liu, Andrew J, Saykin, Roberta D, Brinton, Rima, Kaddurah-Daouk
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES.
Late-onset Alzheimer's disease (LOAD) is a complex neurodegenerative disease characterized by multiple progressive stages, glucose metabolic dysregulation, Alzheimer's disease (AD) pathology, and inexorable cognitive decline. Discovery of metabolic p
Autor:
Sara Moein, Thomas J. Suleski
Publikováno v:
Optics express. 29(24)
Imaging depth of field is shallow in applications with high magnification and high numerical aperture, such as microscopy, resulting in images with in- and out-of-focus regions. Therefore, methods to extend depth of field are of particular interest.