Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Sara McCurdy"'
Autor:
Miguel Alejandro Lopez‐Ramirez, Sara McCurdy, Wenqing Li, Mark K. Haynes, Preston Hale, Karol Francisco, Killian Oukoloff, Matthew Bautista, Chelsea H.J. Choi, Hao Sun, Brendan Gongol, John Y. Shyy, Carlo Ballatore, Larry A. Sklar, Alexandre R. Gingras
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 5, Pp 334-355 (2021)
ABSTRACT The transmembrane protein heart of glass1 (HEG1) directly binds to and recruits Krev interaction trapped protein 1 (KRIT1) to endothelial junctions to form the HEG1–KRIT1 protein complex that establishes and maintains junctional integrity.
Externí odkaz:
https://doaj.org/article/12d216681c9e4a0d9063a1dd1f6e713e
Autor:
Christopher Brampton, Viola Pomozi, Li-Hsieh Chen, Ailea Apana, Sara McCurdy, Janna Zoll, William A. Boisvert, Gilles Lambert, Daniel Henrion, Simon Blanchard, Sheree Kuo, Georges Leftheriotis, Ludovic Martin, Olivier Le Saux
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract ABCC6 deficiency promotes ectopic calcification; however, circumstantial evidence suggested that ABCC6 may also influence atherosclerosis. The present study addressed the role of ABCC6 in atherosclerosis using Ldlr −/− mice and pseudoxan
Externí odkaz:
https://doaj.org/article/095f67c8ae604bf686f99d9c7ce0ab63
Autor:
Jonathan Yap, Sara McCurdy, Martin Alcala, Jason Irei, Jan Garo, Whitney Regan, Bog-Hieu Lee, Shiro Kitamoto, William A. Boisvert
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
ObjectiveTo determine whether overexpression of the chitin degrading enzyme, chitotriosidase (CHIT1), modulates macrophage function and ameliorates atherosclerosis.Approach and ResultsUsing a mouse model that conditionally overexpresses CHIT1 in macr
Externí odkaz:
https://doaj.org/article/9477978701944af2a97d2448d1cacdf2
Autor:
Yvonne Baumer, Sara McCurdy, Tina M. Weatherby, Nehal N. Mehta, Stefan Halbherr, Pascal Halbherr, Noboru Yamazaki, William A. Boisvert
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Atherosclerosis is characterized by subendothelial lipid retention believed to be the result of endothelial trancytosis. Here, the authors show that endothelium can take up and process LDL, generating cholesterol crystals that are deposited on the ba
Externí odkaz:
https://doaj.org/article/09a229c662fe4fe4a530175d5d4ee89e
Autor:
Claire C Bristow, Tatum D Mortimer, Sheldon Morris, Yonatan H Grad, Olusegun O Soge, Erika Wakatake, Rushlenne Pascual, Sara McCurdy Murphy, Kyra E Fryling, Paul C Adamson, Jo-Anne Dillon, Nidhi R Parmar, Hai Ha Long Le, Hung Van Le, Reyna Margarita Ovalles Ureña, Nireshni Mitchev, Koleka Mlisana, Teodora Wi, Samuel P Dickson, Jeffrey D Klausner
Publikováno v:
The Journal of Infectious Diseases. 227:917-925
Background Neisseria gonorrhoeae is a major public health problem due to increasing incidence and antimicrobial resistance. Genetic markers of reduced susceptibility have been identified; the extent to which those are representative of global antimic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41195684c05f96ef8c2f2b23e7df679e
https://doi.org/10.1093/infdis/jiad027
https://doi.org/10.1093/infdis/jiad027
Akademický článek
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Autor:
Kottil W. Rammohan, June Halper, Steven Lang, Sara McCurdy Murphy, Lisa Patton, Courtney Goodman, David K.B. Li
Publikováno v:
Int J MS Care
Although many regional multiple sclerosis (MS) databases existed in the United States and Canada, there was no single clinician-derived registry that examined this disease as a group across the North American continent. This distinction is important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0dc3f15c10cfb15fbb1e0408e82b03f
https://doi.org/10.7224/1537-2073.2021-021
https://doi.org/10.7224/1537-2073.2021-021
Autor:
Sara McCurdy, Jenny Lin, Robert Shenkar, Thomas Moore, Rhonda Lightle, Eva Faurobert, Miguel‐Alejandro Lopez‐Ramirez, Issam Awad, Mark H. Ginsberg
Publikováno v:
FASEB Journal
FASEB Journal, 2022, 36 (12), pp.e22629. ⟨10.1096/fj.202200907RR⟩
FASEB Journal, 2022, 36 (12), pp.e22629. ⟨10.1096/fj.202200907RR⟩
International audience; β1 integrins are important in blood vessel formation and function, finely tuning the adhesion of endothelial cells to each other and to the extracellular matrix. The role of integrins in the vascular disease, cerebral caverno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816ea76eaad7290896f9d0d1b2bfd199
https://pubmed.ncbi.nlm.nih.gov/36349990
https://pubmed.ncbi.nlm.nih.gov/36349990
Autor:
Sharbel G. Romanos, Abhinav Srinath, Ying Li, Bingqing Xie, Chang Chen, Yan Li, Thomas Moore, Dehua Bi, Je Yeong Sone, Rhonda Lightle, Nick Hobson, Dongdong Zhang, Janne Koskimäki, Le Shen, Sara McCurdy, Catherine Chinhchu Lai, Agnieszka Stadnik, Kristina Piedad, Julián Carrión-Penagos, Abdallah Shkoukani, Daniel Snellings, Robert Shenkar, Dinanath Sulakhe, Yuan Ji, Miguel A. Lopez-Ramirez, Mark L. Kahn, Douglas A. Marchuk, Mark H. Ginsberg, Romuald Girard, Issam A. Awad
Publikováno v:
Translational Stroke Research.
Patients with familial cerebral cavernous malformation (CCM) inherit germline loss of function mutations and are susceptible to progressive development of brain lesions and neurological sequelae during their lifetime. To date, no homologous circulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7860ff178fb7dbcf96e7e9e5813b35bf
https://doi.org/10.1007/s12975-022-01050-3
https://doi.org/10.1007/s12975-022-01050-3
Autor:
Daniel Henrion, Janna Zoll, Viola Pomozi, Li-Hsieh Chen, Ludovic Martin, Christopher Brampton, William A. Boisvert, Sheree Kuo, Sara McCurdy, Georges Leftheriotis, Ailea Apana, Simon Blanchard, Olivier Le Saux, Gilles Lambert
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports, 2021, 11 (1), pp.3881. ⟨10.1038/s41598-021-82966-y⟩
Scientific Reports
Scientific Reports, 2021, 11 (1), pp.3881. ⟨10.1038/s41598-021-82966-y⟩
ABCC6 deficiency promotes ectopic calcification; however, circumstantial evidence suggested that ABCC6 may also influence atherosclerosis. The present study addressed the role of ABCC6 in atherosclerosis using Ldlr−/− mice and pseudoxanthoma elas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c30f06b2a8cb95eb39fc8a681165f3
https://doaj.org/article/095f67c8ae604bf686f99d9c7ce0ab63
https://doaj.org/article/095f67c8ae604bf686f99d9c7ce0ab63