Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sara Marrero-Hernández"'
Autor:
Sara Marrero-Hernández, Daniel Márquez-Arce, Romina Cabrera-Rodríguez, Judith Estévez-Herrera, Silvia Pérez-Yanes, Jonathan Barroso-González, Ricardo Madrid, José-David Machado, Julià Blanco, Agustín Valenzuela-Fernández
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
HIV Nef is a central auxiliary protein in HIV infection and pathogenesis. Our results indicate that HDAC6 promotes the aggresome/autophagic degradation of the viral polyprotein Pr55Gag to inhibit HIV-1 production. Nef counteracts this antiviral activ
Externí odkaz:
https://doaj.org/article/29d60b530a264db38f12f86bb3308796
Autor:
Concepción Casado, Sara Marrero-Hernández, Daniel Márquez-Arce, María Pernas, Sílvia Marfil, Ferran Borràs-Grañana, Isabel Olivares, Romina Cabrera-Rodríguez, María-Soledad Valera, Laura de Armas-Rillo, Philippe Lemey, Julià Blanco, Agustín Valenzuela-Fernández, Cecilio Lopez-Galíndez
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT A small group of HIV-1-infected individuals, called long-term nonprogressors (LTNPs), and in particular a subgroup of LTNPs, elite controllers (LTNP-ECs), display permanent control of viral replication and lack of clinical progression. This
Externí odkaz:
https://doaj.org/article/b9c065f676794e36920b4671b9e28c10
Autor:
P. Mark Hogarth, Suellen Nicholson, Charani Ranasinghe, Daniel Watterson, Stavroula Corby, Bruce D. Wines, Zheyi Li, Francesca L Mordant, Damian F. J. Purcell, Christina L Henderson, Thi H. O. Nguyen, Peter Tapley, Michael S. Avumegah, Thomas Holgate, Paula Clarisa Ellenberg, Kevin J. Selva, Stacey T. M. Cheung, Luca Hensen, James G. Barnes, Naphak Modhiran, Paul M. Griffin, Katherine Kedzierska, Wuji Zhang, Kanta Subbarao, Danushka K. Wijesundara, Mai H. Tran, Patrick C. Reading, Trent P. Munro, Paul R. Young, Julia Lackenby, Amy W. Chung, Keith J. Chappell, Sara Marrero-Hernández, Kym Hoger, Jillian Bennet
Publikováno v:
The Lancet. Infectious Diseases
Background: Given the scale of the ongoing COVID-19 pandemic, the development of vaccines based on different platforms is essential, particularly in light of emerging viral variants, the absence of information on vaccine-induced immune durability, an
Autor:
Naphak Modhiran, Bruce D. Wines, Paul R. Young, Katherine Kedzierska, Zhuofeng Li, Francesca L Mordant, Mai H. Tran, Paula Clarisa Ellenberg, Kevin J. Selva, Henderson Cl, Kym Hoger, Daniel Watterson, Suellen Nicholson, Keith J. Chappell, Thomas Holgate, Julia Lackenby, Patrick C. Reading, Bennet J, Luca Hensen, Danushka K. Wijesundara, Nguyen Tho, Amy W. Chung, Peter Tapley, Hogarth Pm, Stacey T. M. Cheung, Trent P. Munro, Damian F. J. Purcell, Charani Ranasinghe, Kanta Subbarao, Corby S, Sara Marrero-Hernández, Michael S. Avumegah
Publikováno v:
SSRN Electronic Journal.
Background: We assessed the safety and immunogenicity of an MF59-adjuvanted subunit vaccine for COVID-19 based on recombinant SARS-CoV-2 spike glycoprotein stabilised in a prefusion conformation by a novel molecular clamp (Sclamp). Methods: Phase 1,
Autor:
Lucile Espert, Daniel Márquez-Arce, Bonaventura Clotet, Judith Estévez-Herrera, Romina Cabrera-Rodríguez, Isabel Olivares, Martine Biard-Piechaczyk, Cecilio López-Galíndez, Cecilia Cabrera, Veronique Hebmann, Agustín Valenzuela-Fernández, Silvia Marfil, Silvia Pérez-Yanes, Maria Pernas, Victor Urrea, Concepción Casado, Sara Marrero-Hernández, Julià Blanco
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-42075-3⟩
Repisalud
Instituto de Salud Carlos III (ISCIII)
Scientific Reports, Nature Publishing Group, 2019, 9, pp.5544. ⟨10.1038/s41598-019-42075-3⟩
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-42075-3⟩
Repisalud
Instituto de Salud Carlos III (ISCIII)
Scientific Reports, Nature Publishing Group, 2019, 9, pp.5544. ⟨10.1038/s41598-019-42075-3⟩
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
In untreated HIV-1-infected individuals, viremia is positively associated with disease progression. However, some viremic non progressors (VNPs) individuals show paradoxical high CD4+ T cell counts. HIV-1 envelope glycoprotein complex (Env) is a majo
Autor:
Sara Marrero-Hernández, María-Soledad Valera, Agustín Valenzuela-Fernández, Laura de Armas-Rillo
Publikováno v:
Reviews in Medical Virology
Summary Viral replication and spreading are fundamental events in the viral life cycle, accounting for the assembly and egression of nascent virions, events that are directly associated with viral pathogenesis in target hosts. These processes occur i
Autor:
Francisco M. Pinto, Idaira Dorta, Sara Marrero-Hernández, Delia Báez, Ayoze González-Santana, A. R. Bello, Mariano Hernández, Teresa A. Almeida, Luz Candenas
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
[Objective] To study the expression levels of tachykinins and tachykinin receptors in uterine leiomyomas and matched myometrium.
[Design] Laboratory study.
[Setting] University research laboratories and academic hospital.
[Patient(s)]
[Design] Laboratory study.
[Setting] University research laboratories and academic hospital.
[Patient(s)]
Autor:
Noé Dubois, Laura García-Expósito, Martine Biard-Piechaczyk, Jean-Christophe Paillart, Agustín Valenzuela-Fernández, Sophie Borel, Serena Ziglio, María-Soledad Valera, Sara Marrero-Hernández, Julien Batisse, Jonathan Barroso-González, Laura de Armas-Rillo
Publikováno v:
Retrovirology
Background Human immunodeficiency virus type 1 (HIV-1) has evolved a complex strategy to overcome the immune barriers it encounters throughout an organism thanks to its viral infectivity factor (Vif), a key protein for HIV-1 infectivity and in vivo p