Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sara Marie D. Komenan"'
Autor:
Helena Escuin-Ordinas, Shuoran Li, Michael W. Xie, Lu Sun, Willy Hugo, Rong Rong Huang, Jing Jiao, Felipe Meira de-Faria, Susan Realegeno, Paige Krystofinski, Ariel Azhdam, Sara Marie D. Komenan, Mohammad Atefi, Begoña Comin-Anduix, Matteo Pellegrini, Alistair J. Cochran, Robert L. Modlin, Harvey R. Herschman, Roger S. Lo, William H. McBride, Tatiana Segura, Antoni Ribas
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
BRAF inhibitors often show skin-hyperproliferative side effects in melanoma patients. Here, the authors demonstrate that BRAF inhibitors can be used to enhance skin wound healing through the MAPK- ERK pathway activation that positively regulates the
Externí odkaz:
https://doaj.org/article/4df7cfd06ae5433d88273671aa9365b6
Autor:
Mohammad Atefi, Rong Rong Huang, Begoña Comin-Anduix, Felipe Meira de-Faria, Ariel M. Azhdam, Jing Jiao, Roger S. Lo, Michael W. Xie, Tatiana Segura, Helena Escuin-Ordinas, Robert L. Modlin, Alistair J. Cochran, Paige Krystofinski, Willy Hugo, Harvey R. Herschman, Shuoran Li, Antoni Ribas, Sara Marie D. Komenan, Susan Realegeno, William H. McBride, Matteo Pellegrini, Lu Sun
Publikováno v:
Nature Communications
Nature communications, vol 7, iss 1
Escuin-Ordinas, H; Li, S; Xie, MW; Sun, L; Hugo, W; Huang, RR; et al.(2016). Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors. Nature communications, 7, 12348. doi: 10.1038/ncomms12348. UCLA: Retrieved from: http://www.escholarship.org/uc/item/7795w71z
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature communications, vol 7, iss 1
Escuin-Ordinas, H; Li, S; Xie, MW; Sun, L; Hugo, W; Huang, RR; et al.(2016). Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors. Nature communications, 7, 12348. doi: 10.1038/ncomms12348. UCLA: Retrieved from: http://www.escholarship.org/uc/item/7795w71z
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
BRAF inhibitors are highly effective therapies for the treatment of BRAFV600-mutated melanoma, with the main toxicity being a variety of hyperproliferative skin conditions due to paradoxical activation of the mitogen-activated protein kinase (MAPK) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4300fadf6f4854d5c661095321320a48
https://pubmed.ncbi.nlm.nih.gov/27476449
https://pubmed.ncbi.nlm.nih.gov/27476449
Autor:
Beata Berent-Maoz, Gardenia Cheung-Lau, Cristina Puig-Saus, Agustin Vega-Crespo, Salemiz Sandoval, Sara Marie D. Komenan, Ruixue Zhang, James M. McCabe, Justin Saco, Paula Kaplan-Lefko, Paige Krystofinski, Donald B. Kohn, Nhat Truong, Antoni Ribas, Mignonette H. Macabali, Begoña Comin-Anduix, Giulia Parisi, Angel Garcia-Diaz
Publikováno v:
Cancer Research. 77:3765-3765
T cell receptor (TCR) engineered adoptive T cell transfer (ACT) has shown remarkable antitumor efficacy in several clinical trials. However, low persistence of modified cells limits long-term clinical responses. To overcome this hurdle, we propose a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e422c71e18298b856436600b0a92db85
https://doi.org/10.1158/1538-7445.am2017-3765
https://doi.org/10.1158/1538-7445.am2017-3765
Autor:
Antoni Ribas, Helena Escuin-Ordinas, Angel Garcia-Diaz, Nicolaos Palaskas, Thomas G. Graeber, Sara Marie D. Komenan, Begonya Comin-Anduix, Daniel Sanghoon Shin
Publikováno v:
Cancer Research. 75:5013-5013
Introduction. The role of PD-L1 as a predictive biomarker for response to PD-1 blockade is unclear. Emerging evidence, including our findings reported here, suggests that PD-L1 expression is important only when induced by the presence of T cells prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e4268759b92d495ed0abbbffd103348
https://doi.org/10.1158/1538-7445.am2015-5013
https://doi.org/10.1158/1538-7445.am2015-5013