Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sara Marie Atkinson"'
Autor:
Theis Christian Tønnessen, Arne Olav Melleby, Ida Marie Hauge-Iversen, Emil Knut Stenersen Espe, Mohammed Shakil Ahmed, Thor Ueland, Espen Andre Haavardsholm, Sara Marie Atkinson, Espen Melum, Håvard Attramadal, Ivar Sjaastad, Leif Erik Vinge
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262821 (2022)
AimsPatients with rheumatoid arthritis (RA) have increased risk of heart failure (HF). The mechanisms and cardiac prerequisites explaining this association remain unresolved. In this study, we sought to determine the potential cardiac impact of an ex
Externí odkaz:
https://doaj.org/article/96fa321cee4146c688a05b660af2d1f4
Autor:
Sara Marie Atkinson, Ute Hoffmann, Alf Hamann, Emil Bach, Niels Banhos Danneskiold-Samsøe, Karsten Kristiansen, Kyle Serikawa, Brian Fox, Kim Kruse, Claus Haase, Søren Skov, Anneline Nansen
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 4, Pp 427-440 (2016)
Rodent models of arthritis have been extensively used in the elucidation of rheumatoid arthritis (RA) pathogenesis and are instrumental in the development of therapeutic strategies. Here we utilise delayed-type hypersensitivity arthritis (DTHA), a mo
Externí odkaz:
https://doaj.org/article/5ed44e8c71e447e2b7d84fa30b0d84ec
Autor:
Anneline Nansen, Sara Marie Atkinson
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 120:108-114
In this MiniReview, we summarize the body of knowledge on the delayed-type hypersensitivity arthritis (DTHA) model, a recently developed arthritis model with 100% incidence, low variation and synchronized onset in C57BL/6 (B6) mice, and compare it to
Autor:
Kyle Serikawa, Alf Hamann, Sara Marie Atkinson, Ute Hoffmann, Claus Haase, Søren Skov, Emil Bach, Karsten Kristiansen, Kim Kruse, Brian A. Fox, Anneline Nansen, Niels Banhos Danneskiold-Samsøe
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 4, Pp 427-440 (2016)
Disease Models & Mechanisms
Atkinson, S M, Hoffmann, U, Bach, E, Danneskiold-Samsøe, N B, Kristiansen, K, Serikawa, K, Fox, B, Kruse, K, Haase, C, Skov, S & Nansen, A 2016, ' Depletion of regulatory T cells leads to an exacerbation of delayedtype hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade ', Disease Models & Mechanisms, vol. 9, pp. 427-440 . https://doi.org/10.1242/dmm.022905
Disease Models & Mechanisms
Atkinson, S M, Hoffmann, U, Bach, E, Danneskiold-Samsøe, N B, Kristiansen, K, Serikawa, K, Fox, B, Kruse, K, Haase, C, Skov, S & Nansen, A 2016, ' Depletion of regulatory T cells leads to an exacerbation of delayedtype hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade ', Disease Models & Mechanisms, vol. 9, pp. 427-440 . https://doi.org/10.1242/dmm.022905
Rodent models of arthritis have been extensively used in the elucidation of rheumatoid arthritis (RA) pathogenesis and are instrumental in the development of therapeutic strategies. Here we utilise delayed-type hypersensitivity arthritis (DTHA), a mo
Autor:
Claus Haase, Anneline Nansen, Anja A. Kühl, Mette Thorn, Brian A. Fox, J. Bleil, Kyle Serikawa, Søren Skov, R. Maier, Kim Kruse, Sara Marie Atkinson, Uta Syrbe
Publikováno v:
Atkinson, S M, Bleil, J, Maier, R, Kuehl, A A, Thorn, M, Serikawa, K, Fox, B, Kruse, K, Haase, C, Skov, S, Nansen, A & Syrbe, U 2016, ' Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model ', Arthritis Research & Therapy, vol. 18, 28 . https://doi.org/10.1186/s13075-016-0931-3
Arthritis Research & Therapy
Arthritis Research & Therapy
Background: The aims of the present study were to determine the relationship between bone destruction and bone formation in the delayed-type hypersensitivity arthritis (DTHA) model and to evaluate the effect of receptor activator of nuclear factor ka
Autor:
Lars Hornum, Charles R. Mackay, Claus Haase, Bodil-Cecilie Sondergaard, Søren Skov, Anneline Nansen, Chih-Chuan Chang, Renhong Tang, Birgitte Nissen Friedrichsen, Sara Marie Atkinson, Pernille A Usher
Publikováno v:
Atkinson, S M, Nansen, A, Usher, P A, Sondergaard, B-C, Mackay, C R, Friedrichsen, B, Chang, C-C, Tang, R, Skov, S, Haase, C & Hornum, L 2015, ' Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model ', Autoimmunity, vol. 48, no. 7, pp. 460-470 . https://doi.org/10.3109/08916934.2015.1031888
Blockade of the complement cascade at the C5a/C5a receptor (C5aR)-axis is believed to be an attractive treatment avenue in rheumatoid arthritis (RA). However, the effects of such interventions during the early phases of arthritis remain to be clarifi
Autor:
Søren Skov, Anneline Nansen, J. Bleil, Anja A. Kühl, M. Thorn, Claus Haase, Uta Syrbe, Sara Marie Atkinson
Publikováno v:
Annals of the Rheumatic Diseases. 74:927.2-927
Background The delayed-type hypersensitivity arthritis (DTHA) model combines collagen type II antibody (anti-CII) treatment with local DTH induction in the footpad [1] which induces a strong arthritis accompanied by bone destruction and excessive per
Publikováno v:
Annals of the Rheumatic Diseases. 72:A809.4-A810
Background C5a is an anaphylatoxin generated in response to complement activation. C5a promotes leukocyte chemotaxis and activation via the C5a receptor (C5aR), both directly on C5aR-positive cells such as neutrophils, monocytes and macrophages, and
Autor:
Claus Haase, Helle Markholst, Anneline Nansen, Pernille A Usher, Sara Marie Atkinson, Peter Helding Kvist
Publikováno v:
Arthritis Research & Therapy
Introduction Rheumatoid arthritis (RA) is a chronic progressive, inflammatory and destructive autoimmune disease, characterised by synovial joint inflammation and bone erosion. To better understand the pathophysiology and underlying immune mechanisms