Blood-based biological ageing and red cell distribution width are associated with prevalent Parkinson’s disease: findings from a large Italian population cohort

Autor: Alessandro Gialluisi, Alfonsina Tirozzi, Simona Costanzo, Maria Ilenia De Bartolo, Daniele Belvisi, Sara Magnacca, Amalia De Curtis, Stefania Falciglia, Moreno Ricci, Chiara Cerletti, Maria Benedetta Donati, Alfredo Berardelli, Giovanni de Gaetano, Licia Iacoviello

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

BackgroundAging clocks tag the actual underlying age of an organism and its discrepancy with chronological age and have been reported to predict incident disease risk in the general population. However, the relationship with neurodegenerative risk an

Externí odkaz: https://doaj.org/article/c69e02a8bc45410b99f05ffd5d0d517e

Rationale and design of the CV-PREVITAL study: an Italian multiple cohort randomised controlled trial investigating innovative digital strategies in primary cardiovascular prevention

Autor: Roberta Pastorino, Eloisa Arbustini, Andrea Faini, Gianfranco Parati, Grzegorz Bilo, Davide Soranna, Antonella Zambon, Sergio Leonardi, Alessandro Gialluisi, Lorenzo Giovanni Mantovani, Walter Ricciardi, Fabio Blandini, Giovanni Scambia, Catherine Klersy, Marialaura Bonaccio, Augusto Di Castelnuovo, Simona Costanzo, Amalia De Curtis, Mariarosaria Persichillo, Chiara Cerletti, Maria Benedetta Donati, Licia Iacoviello, Giuseppe Remuzzi, Camilla Torlasco, Giuseppe Ambrosio, Gabriele Zoppoli, Maria Chiara Grimaldi, Daniela Pedicino, Giovanna Liuzzo, Serena Pelusi, Daniele Prati, Luca Valenti, Francesca Gorini, Maurizio Sanguinetti, Giuseppe Ferrante, Gianluigi Condorelli, Giulio Pompilio, Stefania Boccia, Luigi Badano, Victor Savevski, Tiziana Bachetti, Gian Franco Gensini, Silvano Bosari, Alice Bonanni, Elena Tremoli, Angelo Santoliquido, Stefano Genovese, Sara Boveri, Gianfranco Gensini, Francesco Gianfagna, Italo Porto, Fabio Tuzzolino, Carolina Lombardi, Egidio Traversi, Fabrizio Veglia, Andrea Urbani, Domenico D’Amario, Gaetano Antonio Lanza, Antonio Uccelli, José Pablo Werba, Livio Luzi, Pietro Ameri, Davide Gentilini, Luisa Gilardini, Cecilia Invitti, Maurizio Volterrani, Maria Teresa La Rovere, Giovanni Gentile, Francesco Clemenza, Mario Urtis, Francesca Ieva, Maria Carla Roncaglioni, Valentina Milani, Paola Baiardi, Debora Rosa, Fabiana Madotto, Emilia Ruggiero, Teresa Panzera, Simona Esposito, Sara Magnacca, Fabrizia Noro, Roberta Parisi, Francesca Bracone, Irene Baroni, Damiano Baldassarre, Roberta Baetta, Luigi Frati, Pier Giulio Conaldi, Massimo Fini, Antonio Di Malta, Mauro Amato, Alice Bonomi, Francesca Colazzo, Martino Pengo, Luciana Auteri, Marta Baviera, Alberico Catapano, Alexis Elias Malavazos, Serenella Castelvecchio, Massimiliano Marco Corsi-Romanelli, Rosanna Cardani, Valentina Agnese, Bianca Pane, Laura Spinardi, Marco Visconti, Anna Di Blasio, Luisa Ojeda-Fernández, Andreana Foresta, Simonetta Scalvini, Antonia Pierobon, Alessandra Gorini, Annarosa Racca, Manuela Bandi, Lorenzo Menicanti, Gualtiero Colombo, Chiara Vavassori, Maria Luisa Biondi, Beatrice Frigerio, Alessio Ravani, Daniela Sansaro, Daniela Coggi, Alessandra Romandini, Monica Giroli, Mattia Giuliani, Maurizio Rondinelli, Catia Trudu, Carmen Cinieri, Massimo Monturano, Elisa Perger, Lucia Zanotti, Lidia Cova, Luca Grappiolo, Laura Papa, Ignazio Romano, Luisa Ojeda, Fiorenza Clerici, Angela Palumbo, Roberto Mattioli, Ermanno Longhi, Anwal Ghulam, Sabatino Orlandi, Sabrina Franciosa, Martina Morelli, Fiorella De Rita, Giovanni de Gaetano, Massimiliano MarcoCorsi Romanelli, Ambra Cerri, Carola Dubini, Manuel Bruno Trevisan, Laura Valentina Renna, Paola Giubbilini, Lucia Ramputi, Giada DeAngeli, Francesca Olmetti, Maurizio Bussotti, Carlo Gaetano, Martina Balbi, Laura Comini, Monica Lorenzoni, Adriana Olivares, Camilla Garrè, Riccardo Sideri, Giuseppe Caruana, Nicola Cuscino, Gabriele Di Gesaro, Alessio Greco, Italia Loddo, Domenico Palombo, Giovanni Spinella, Gaddiel Mozzetta, Alice Finotello, Giovanni Pratesi, Margherita Clerici, Cristiana Bianco, Rossana Carpani, Giulia Periti, Sara Margarita, Anna Severino, Alessia D’Aiello, Ramona Vinci, Mattia Brecciaroli, Simone Filomia, Luca Proto, Dalila Tarquini, Arianna Elia, Alessia Currao, Alessandro Di Toro, Lorenzo Giuliani, Giuseppe Caminiti, Federica Marcolongo, Barbara Sposato, Fiorella Guadagni, Valentina Morsella, Angelica Marziale, Giulia Protti

Publikováno v: BMJ Open, Vol 13, Iss 7 (2023)

Introduction Prevention of cardiovascular disease (CVD) is of key importance in reducing morbidity, disability and mortality worldwide. Observational studies suggest that digital health interventions can be an effective strategy to reduce cardiovascu

Externí odkaz: https://doaj.org/article/0b48f5d650b049b28dd773c39b063361

Platelet Distribution Width Is Associated with P-Selectin Dependent Platelet Function: Results from the Moli-Family Cohort Study

Autor: Benedetta Izzi, Alessandro Gialluisi, Francesco Gianfagna, Sabatino Orlandi, Amalia De Curtis, Sara Magnacca, Simona Costanzo, Augusto Di Castelnuovo, Maria Benedetta Donati, Giovanni de Gaetano, Marc F. Hoylaerts, Chiara Cerletti, Licia Iacoviello, on behalf of the Moli-family Study Investigators

Publikováno v: Cells, Vol 10, Iss 10, p 2737 (2021)

Defined as an index of platelet size heterogeneity, the platelet distribution width (PDW) is still a poorly characterized marker of platelet function in (sub)clinical disease. We presently validated PDW as a marker of P-selectin dependent platelet ac

Externí odkaz: https://doaj.org/article/884491ad29cb4fe3b34e50b3f207e497

Combined influence of depression severity and low-grade inflammation on incident hospitalization and mortality risk in Italian adults

Autor: Chiara Cerletti, Augusto Di Castelnuovo, Simona Costanzo, Alessandro Gialluisi, Licia Iacoviello, Francesca Bracone, Amalia De Curtis, Marialaura Bonaccio, Giovanni de Gaetano, Moli-sani Study Investigators, Sara Magnacca, Maria Benedetta Donati

Publikováno v: Journal of Affective Disorders. 279:173-182

Background Depression and low-grade systemic inflammation are associated risk factors for hospitalizations and mortality, although the nature of this relationship is under-investigated. Methods We performed multivariable Cox regressions of first hosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4048d5f98f4bec2a64ce71c9747d0f
https://doi.org/10.1016/j.jad.2020.10.004

Abstract MP73: Ultra-processed Food Intake And All-cause And Cause-specific Mortality In Subjects With Type 2 Diabetes: Longitudinal Findings From The Moli-sani Study

Autor: Marialaura Bonaccio, Simona Costanzo, Augusto Di Castelnuovo, Mariarosaria Persichillo, Sara Magnacca, Amalia De Curtis, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello

Publikováno v: Circulation. 145

Introduction: Excessive consumption of ultra-processed food (UPF) is associated with increased risk of mortality and disease in general populations but its health impact for individuals with type 2 diabetes is poorly defined. Hypothesis: We assessed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b491cd1b6cce6218ea506a84673d6211
https://doi.org/10.1161/circ.145.suppl_1.mp73