Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sara M. Reed"'
Publikováno v:
Management Science. 68:280-299
We demonstrate that autonomous-assisted delivery can yield significant improvements relative to today’s system in which a delivery person must park the vehicle before delivering packages. We model an autonomous vehicle that can drop off the deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e06728683a75a682ac48b1a7d93bac2
https://doi.org/10.1287/mnsc.2020.3917
https://doi.org/10.1287/mnsc.2020.3917
Autor:
Dawn E. Quelle, Benjamin W. Darbro, James R. Howe, Andrew M. Bellizzi, Thomas M. O'Dorisio, Scott K. Sherman, Ryan W. Askeland, Heather J. Major, Aloysius J. Klingelhutz, Francoise A. Gourronc, Frederick W. Quelle, Agshin F. Taghiyev, Sara M. Reed, Kelly C. Falls, Viviane P. Muniz, Jussara Hagen
Figure S2. Representative IPA mechanistic network for signaling regulators predicted to contribute to the RABL6A knockdown phenotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb316efa37fe042ca5e2c480aebbbc9
https://doi.org/10.1158/0008-5472.22404263.v1
https://doi.org/10.1158/0008-5472.22404263.v1
Autor:
Dawn E. Quelle, Benjamin W. Darbro, James R. Howe, Andrew M. Bellizzi, Thomas M. O'Dorisio, Scott K. Sherman, Ryan W. Askeland, Heather J. Major, Aloysius J. Klingelhutz, Francoise A. Gourronc, Frederick W. Quelle, Agshin F. Taghiyev, Sara M. Reed, Kelly C. Falls, Viviane P. Muniz, Jussara Hagen
Table S1. List of differentially regulated genes caused by RABL6A knockdown (KD), relative to control (CON), in BON-1 PNET cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b710410caa0071f21f915ebf926f36c
https://doi.org/10.1158/0008-5472.22404248.v1
https://doi.org/10.1158/0008-5472.22404248.v1
Autor:
Sara M Reed, Jussara Hagen, Viviane P Muniz, Timothy R Rosean, Nick Borcherding, Sebastian Sciegienka, J Adam Goeken, Paul W Naumann, Weizhou Zhang, Van S Tompkins, Siegfried Janz, David K Meyerholz, Dawn E Quelle
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112126 (2014)
Nuclear Interactor of ARF and Mdm2 (NIAM, gene designation Tbrg1) is a largely unstudied inhibitor of cell proliferation that helps maintain chromosomal stability. It is a novel activator of the ARF-Mdm2-Tip60-p53 tumor suppressor pathway as well as
Externí odkaz:
https://doaj.org/article/9c544ff0f4564561a32fe2479115b285
Autor:
Kelly C. Falls, Thomas M. O'Dorisio, Aloysius J. Klingelhutz, Sara M. Reed, Scott K. Sherman, Benjamin W. Darbro, Dawn E. Quelle, Frederick W. Quelle, Heather J. Major, James R. Howe, Viviane P. Muniz, Andrew M. Bellizzi, Agshin F. Taghiyev, Francoise A. Gourronc, Ryan W. Askeland, Jussara Hagen
Publikováno v:
Cancer research. 74(22)
Mechanisms of neuroendocrine tumor (NET) proliferation are poorly understood, and therapies that effectively control NET progression and metastatic disease are limited. We found amplification of a putative oncogene, RABL6A, in primary human pancreati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80ee1f9896ebddaa3442047aeb1be2b
https://pubmed.ncbi.nlm.nih.gov/25273089
https://pubmed.ncbi.nlm.nih.gov/25273089
Publikováno v:
Cell cycle (Georgetown, Tex.). 13(10)
ARF, the alternative reading frame protein encoded by the Ink4a-ARF (Cdkn2a) locus, is best known for suppressing cancer through p53-dependent and p53-independent pathways.1 Although less widely appreciated, ARF is also important in development. Loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b74f1201eac8203e972cd8112baea2
https://pubmed.ncbi.nlm.nih.gov/24401748
https://pubmed.ncbi.nlm.nih.gov/24401748
Autor:
Van S. Tompkins, Jussara Hagen, Sara M. Reed, Dawn E. Quelle, Frederick W. Quelle, Katie A. Thies
The p53 tumor suppressor is controlled by an interactive network of factors that stimulate or inhibit its transcriptional activity. Within that network, Mdm2 functions as the major antagonist of p53 by promoting its ubiquitylation and degradation. Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9b383b9234fc5a4147b8e663cf11d1
https://europepmc.org/articles/PMC4049965/
https://europepmc.org/articles/PMC4049965/
Autor:
Jussara Hagen, Dawn E. Quelle, Van S. Tompkins, Paul W. Naumann, Timothy R. Rosean, Viviane P. Muniz, Sara M. Reed, J. Adam Goeken, Weizhou Zhang, Siegfried Janz, David K. Meyerholz, Nicholas Borcherding, Sebastian Sciegienka
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e112126 (2014)
PLoS ONE, Vol 9, Iss 11, p e112126 (2014)
Nuclear Interactor of ARF and Mdm2 (NIAM, gene designation Tbrg1) is a largely unstudied inhibitor of cell proliferation that helps maintain chromosomal stability. It is a novel activator of the ARF-Mdm2-Tip60-p53 tumor suppressor pathway as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af3fba95d3c577d4c4b9c45eb390dc3
https://doi.org/10.1371/journal.pone.0112126
https://doi.org/10.1371/journal.pone.0112126
Autor:
Van S. Tompkins, Jussara Hagen, Dawn E. Quelle, Sara M. Reed, Diane E. Cryderman, Katie A. Thies, Lori L. Wallrath
Publikováno v:
Cancer Research. 72:215-215
Nuclear interactor of ARF and Mdm2, NIAM, is a novel regulator of the ARF-Mdm2-p53 tumor suppressor pathway. It collaborates with ARF, promotes p53 transcriptional activity, and is negatively regulated by Mdm2-mediated ubiquitination and proteasome d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16ec334e3df720f814267921c7768ed9
https://doi.org/10.1158/1538-7445.am2012-215
https://doi.org/10.1158/1538-7445.am2012-215
Autor:
Ryan A. Askeland, Xuefeng Zhang, Tarik Jamar Smith, Jamie A. Weydert, Kokou D. Zamba, Van S. Tompkins, Sara M. Reed, Dawn E. Quelle, James J. Mezhir, Matthew P. Fitzgerald, Viviane P. Muniz, Anna M. Button, Brian J. Smith, Frederick E. Domann, Jussara Hagen
Publikováno v:
Cancer Research. 72:712-712
Pancreatic ductal adenocarcinoma (PDAC) is an incurable malignancy with ineffective treatments and dismal median survival. The INK4a/ARF locus, which encodes the alternative reading frame (ARF) tumor suppressor, is commonly inactivated in PDAC tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b433e6eb50601589a460829a88c01bf1
https://doi.org/10.1158/1538-7445.am2012-712
https://doi.org/10.1158/1538-7445.am2012-712