Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sara M. Molinas"'
Autor:
Sara M. Molinas, Liliana Alicia Monasterolo, Marco A. Brovedan, Gerardo Daniel Pisani, Laura Trumper
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Acetaminophen (APAP) is a widely prescribed analgesic and antipyretic drug. In the present work, we studied the effects of glutamine (Gln) in an in vivo model of APAP-induced nephrotoxicity in male Wistar rats. Renal function, histological characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6560445a75c113672711230fa777d6d0
https://doi.org/10.1139/cjpp-2017-0423
https://doi.org/10.1139/cjpp-2017-0423
Autor:
Melina A. Pagotto, Trinidad Raices, Sara M. Molinas, Gerardo B. Pisani, María Lorena Roldán, Liliana Alicia Monasterolo, Omar Pedro Pignataro
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Accumulating evidence indicates the association between changes in circulating sex steroid hormone levels and the development of diabetic nephropathy. However, the renal synthesis of steroid hormones during diabetes is essentially unknown. Male Wista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70cc19508b8258391e85aa3c92941a2d
https://doi.org/10.1016/j.mce.2021.111170
https://doi.org/10.1016/j.mce.2021.111170
Acidosis-induced downregulation of hepatocyte mitochondrial aquaporin-8 and ureagenesis from ammonia
Autor:
Laura Trumper, Mauro Danielli, Julieta Marrone, Sara M. Molinas, Raúl A. Marinelli, Leandro Raul Soria
Publikováno v:
Biochemistry and Cell Biology. 93:417-420
It has been proposed that during metabolic acidosis, the liver downregulates mitochondrial ammonia detoxification via ureagenesis, a bicarbonate-consuming process. Since we previously demonstrated that hepatocyte mitochondrial aquaporin-8 channels (m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1313b3c18f78f117a38d8ec9f306dce
https://doi.org/10.1139/bcb-2014-0168
https://doi.org/10.1139/bcb-2014-0168
Publikováno v:
American Journal of Physiology-Renal Physiology. 303:F458-F466
Mitochondrial ammonia synthesis in proximal tubules and its urinary excretion are key components of the renal response to maintain acid-base balance during metabolic acidosis. Since aquaporin-8 (AQP8) facilitates transport of ammonia and is localized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a3f5c1bacdc97c26a9f29626fee71c
https://doi.org/10.1152/ajprenal.00226.2012
https://doi.org/10.1152/ajprenal.00226.2012
Autor:
Sara M. Molinas, Stella Mahieu, María Mónica Elías, Marcela González, María del Carmen Contini, Néstor Millen
Publikováno v:
Toxicology. 223:209-218
The aim of this work was to study the effects of chronic administration of aluminum (Al) on the urinary concentrating and diluting mechanisms in the distal tubules and collecting ducts. Male Wistar rats were chronically treated with aluminum lactate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2dccbc8089dbf1758da6af1f9d46add
https://doi.org/10.1016/j.tox.2006.03.018
https://doi.org/10.1016/j.tox.2006.03.018
Publikováno v:
Molecular and Cellular Biochemistry. 287:33-42
The aim of the present work was to study the effects of an unilateral ischaemic-reperfusion injury on Na+, K+-ATPase activity, alpha1 and beta1 subunits protein and mRNA abundance and ATP content in cortical and medullary tissues from postischaemic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06bccae097abfa1248095cc2b1bd6889
https://doi.org/10.1007/s11010-005-9021-6
https://doi.org/10.1007/s11010-005-9021-6
Autor:
Guillermo L. Lehmann, Sara M. Molinas, Raúl A. Marinelli, Julieta Marrone, Leandro Raul Soria, Giuseppe Calamita
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
We recently reported that hepatocyte mitochondrial aquaporin-8 (mtAQP8) channels facilitate the uptake of ammonia and its metabolism into urea. Here we studied the effect of bacterial lipopolysaccharides (LPS) on ammonia-derived ureagenesis. In LPS-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e70e912498f6a42e39edd5f1660bb76
http://www.sciencedirect.com/science/article/pii/S0014579314002075
http://www.sciencedirect.com/science/article/pii/S0014579314002075
Autor:
Sara M. Molinas, Laura Trumper, María Lorena Roldán, Liliana Alicia Monasterolo, Romina María del Luján Pagotto, Gerardo B. Pisani, María Cristina Lugano, Omar Pedro Pignataro, Melina Andrea Pagotto, Gastón Rogic
Cumulative evidence demonstrated effective downstream metabolism of pregnenolone in renal tissue. The aim of this study was to evaluate the expression and functional activity of cytochrome P450 side chain cleavage enzyme (CYP11A1), which converts cho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b284a6a6a1b842b49939cead046edd
https://www.sciencedirect.com/science/article/pii/S0303720710005083
https://www.sciencedirect.com/science/article/pii/S0303720710005083
Autor:
María Mónica Elías, Cesar Cortés-González, Cristino Cruz, Laura Trumper, Yvett González-Bobadilla, Sara M. Molinas, Norma A. Bobadilla, Liliana Alicia Monasterolo
Publikováno v:
Nephron. Experimental nephrology. 112(1)
Background/Aims: Contributions to the understanding of acute renal failure (ARF) pathogenesis have not been translated into an effective clinical therapy. We studied the effects of pretreatment with the angiotensin II type 1 (AT1) receptor blocker, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311f59f8b670dd2c84a8b3327d1f6639
https://pubmed.ncbi.nlm.nih.gov/19342869
https://pubmed.ncbi.nlm.nih.gov/19342869
Publikováno v:
Molecular and cellular biochemistry. 260(1-2)
Unilateral renal ischemia for 40 min in rat results in increased fibronectin (FN) expression in proximal tubular cells. This study examines the role of 24 h of blood reperfusion and the role of the renin-angiotensin system (RAS) on these results. Rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e4f1dd40b83ce1de2f0bf6ab714d6f
https://pubmed.ncbi.nlm.nih.gov/15228098
https://pubmed.ncbi.nlm.nih.gov/15228098