Výsledky vyhledávání - "Sara M. Lipson"

Akademický článek

Inhibition of both the apical sodium-dependent bile acid transporter and HMG-CoA reductase markedly enhances the clearance of LDL apoB

Autor: Dawn E. Telford, Jane Y. Edwards, Sara M. Lipson, Brian Sutherland, P.Hugh R. Barrett, John R. Burnett, Elaine S. Krul, Bradley T. Keller, Murray W. Huff

Publikováno v: Journal of Lipid Research, Vol 44, Iss 5, Pp 943-952 (2003)

Discovery of the ileal apical sodium-dependent bile acid transporter (ASBT) permitted development of specific inhibitors of bile acid reabsorption, potentially a new class of cholesterol-lowering agents. In the present study, we tested the hypothesis

Externí odkaz: https://doaj.org/article/7c8fb27920264b34957b9666d6ecd11d

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A Novel Inhibitor of Oxidosqualene:Lanosterol Cyclase Inhibits Very Low–Density Lipoprotein Apolipoprotein B100 (ApoB100) Production and Enhances Low-Density Lipoprotein ApoB100 Catabolism Through Marked Reduction in Hepatic Cholesterol Content

Autor: Olivier Morand, Johannes Aebi, Henrietta Dehmlow, Dawn E. Telford, P. Hugh R. Barrett, Murray W. Huff, Sara M. Lipson, Jane Y. Edwards, Brian G. Sutherland

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 25:2608-2614

Objective— Inhibition of 2,3-oxidosqualene:lanosterol cyclase (OSC), an enzyme in the cholesterol synthesis pathway, has the unique ability to inhibit cholesterol synthesis while simultaneously enhancing oxysterol synthesis. Our objectives were to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b7e55fdd891258e2399c38ea76e53a
https://doi.org/10.1161/01.atv.0000189158.28455.94

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Inhibition of both the apical sodium-dependent bile acid transporter and HMG-CoA reductase markedly enhances the clearance of LDL apoB

Autor: P. Hugh R. Barrett, Sara M. Lipson, Elaine S. Krul, Jane Y. Edwards, Bradley T. Keller, John R. Burnett, Murray W. Huff, Dawn E. Telford, Brian G. Sutherland

Publikováno v: Journal of Lipid Research, Vol 44, Iss 5, Pp 943-952 (2003)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f99ab019940c1ee77f91fab67fd27c6
http://www.sciencedirect.com/science/article/pii/S0022227520311408

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