Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sara M. Garrett"'
Autor:
Logan Mlakar, Sara M. Garrett, Tomoya Watanabe, Matthew Sanderson, Tetsuya Nishimoto, Jonathan Heywood, Kristi L. Helke, Joseph M. Pilewski, Erica L. Herzog, Carol Feghali-Bostwick
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2861 (2022)
Organ fibrosis, particularly of the lungs, causes significant morbidity and mortality. Effective treatments are needed to reduce the health burden. A fragment of the carboxyl-terminal end of collagen XVIII/endostatin reduces skin and lung fibrosis. T
Externí odkaz:
https://doaj.org/article/a80803308f4249ff8487842b14caa78d
Autor:
Miran A. Jaffa, Mulugeta Gebregziabher, Sara M. Garrett, Deirdre K. Luttrell, Kenneth E. Lipson, Louis M. Luttrell, Ayad A. Jaffa
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract Background Connective tissue growth factor (CTGF), is a secreted matricellular factor that has been linked to increased risk of cardiovascular disease in diabetic subjects. Despite the biological role of CTGF in diabetes, it still remains un
Externí odkaz:
https://doaj.org/article/54060a598ae846ab86070b0ca4bdbc0d
Publikováno v:
Methods and Protocols, Vol 2, Iss 2, p 45 (2019)
Th17 cells are a subset of effector T helper cells that produce interleukin (IL)-17A, IL-17F, IL-22, and IL-26, which can promote tissue inflammation and contribute to the pathogenesis of rheumatic, fibrosing, and other diseases. Research into these
Externí odkaz:
https://doaj.org/article/f09c63091784456fa0a8ea1c4da9dacf
Autor:
Feghali-Bostwick, Kristy M. Waldrep, Jessalyn I. Rodgers, Sara M. Garrett, Bethany J. Wolf, Carol A.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 14; Pages: 11234
Pulmonary fibrosis (PF) associated with systemic sclerosis (SSc) results in significant morbidity and mortality. We previously reported that insulin-like growth factor-II (IGF-II) is overexpressed in lung tissues and fibroblasts from SSc patients, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::aab52e34af41df7c15b8f1bc10f01d72
Autor:
Nicholas G. Zaorsky, Amar U. Kishan, Ming Wang, Timothy N. Showalter, Daniel M. Trifiletti, J.T. Yang, Vernon M. Chinchilli, David J. DeGraff, Eric J. Lehrer, Henry S. Park, Xi Wang, Christine Lin, Sara M Garrett, Daniel E. Spratt
Publikováno v:
Int J Cancer
Although cancer is highly heterogeneous, all metastatic cancer is considered American Joint Committee on Cancer (AJCC) Stage IV disease. The purpose of this project was to redefine staging of metastatic cancer. Internal validation of nationally repre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb27b303ad80a6952ec0dff3cf28f2b
https://pubmed.ncbi.nlm.nih.gov/34287840
https://pubmed.ncbi.nlm.nih.gov/34287840
Publikováno v:
American Journal of Physiology-Renal Physiology. 314:F260-F268
Our laboratory recently made the novel observation that 5-hydroxytryptamine 1F (5-HT1F) receptor activation induces mitochondrial biogenesis (MB), the production of new, functional mitochondria, in vitro and in vivo. We sought to determine the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ae39a24d747bbcc52bac662ae02030
https://doi.org/10.1152/ajprenal.00324.2017
https://doi.org/10.1152/ajprenal.00324.2017
Autor:
Deirdre K. Luttrell, Sara M. Garrett, Kenneth E. Lipson, Vadt Investigators, Ayad A. Jaffa, Maria F. Lopes-Virella, Louis M. Luttrell, Kelly J. Hunt, Miran A. Jaffa
Publikováno v:
Diabetes Care
OBJECTIVE Connective tissue growth factor (CTGF), also known as CCN2, is a potent chemotactic and extracellular matrix-inducing matricellular protein that has been implicated in progression of inflammatory and fibroproliferative disorders. An emergin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3304df803610501edb770ff65d7c682
https://doi.org/10.2337/dc17-2083
https://doi.org/10.2337/dc17-2083
Autor:
Xi Wang, Eric J. Lehrer, C. Lin, David J. DeGraff, Nicholas G. Zaorsky, J.T. Yang, A.U. Kishan, Henry S. Park, Ming Wang, Sara M Garrett, Daniel M. Trifiletti, Ying Zhang, D.E. Spratt, Timothy N. Showalter
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 111:S64
PURPOSE/OBJECTIVE(S) Staging for metastatic disease is unreliable; there is usually only one category of Stage IV in the American Joint Commission on Cancer (AJCC) 8th edition, but survival can range from weeks to years. We hypothesize that prognosti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a4a6449daadca5d5495bb2c6d9ac64c
https://doi.org/10.1016/j.ijrobp.2021.07.161
https://doi.org/10.1016/j.ijrobp.2021.07.161
Publikováno v:
Journal of Scleroderma and Related Disorders. 2:100-107
Fibroblasts are the effector cells of fibrosis characteristic of systemic sclerosis (SSc, scleroderma) and other fibrosing conditions. The excess production of extracellular matrix (ECM) proteins is the hallmark of fibrosis in different organs, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9063f62dff374831c6aa385cda21a6
https://doi.org/10.5301/jsrd.5000240
https://doi.org/10.5301/jsrd.5000240
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0225422 (2019)
PLoS ONE, Vol 14, Iss 11, p e0225422 (2019)
Type 2 insulin-like growth factor (IGF-II) levels are increased in fibrosing lung diseases such as idiopathic pulmonary fibrosis (IPF) and scleroderma/systemic sclerosis-associated pulmonary fibrosis (SSc). Our goal was to investigate the contributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84885187dfdbe84d8d16aa3334bf1950
http://europepmc.org/articles/PMC6876936
http://europepmc.org/articles/PMC6876936