Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Sara M. El-Ewasy"'
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Akademický článek
Purification, characterization and immunogenicity assessment of glutaminase free L-asparaginase from Streptomyces brollosae NEAE-115
Autor: Noura El-Ahmady El-Naggar, Sahar F. Deraz, Sara M. El-Ewasy, Ghada M. Suddek
Publikováno v: BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-15 (2018)
Abstract Background L-asparaginase is a potential therapeutic enzyme widely used in the chemotherapy protocols of pediatric and adult patients with acute lymphoblastic leukemia. However, its use has been limited by a high rate of hypersensitivity in
Externí odkaz: https://doaj.org/article/3363e94bed1b4712ad3a978d410ebcb8
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2
Bioprocess Optimization for Enhanced Production of L-asparaginase via Two Model-Based Experimental Designs by Alkaliphilic Streptomyces fradiae NEAE-82
Autor: Hoda M. Soliman, Sara M. El-Ewasy, Noura El-A. El-Naggar
Publikováno v: Current Biotechnology. 9:23-37
Background: L-asparaginase is one of the most widely used chemotherapeutic agents for the treatment of a variety of lymphoproliferative disorders and particularly acute lymphoblastic leukemia. Due to increased applications of L-asparaginase in severa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::101f1098f56f0f2b97dc7cd8393db972
https://doi.org/10.2174/2211550109666200206100445
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3
Process development for scale-up production of a therapeutic L-asparaginase by Streptomyces brollosae NEAE-115 from shake flasks to bioreactor
Autor: Sara M. El-Ewasy, Nayera A. M. Abdelwahed, Noura El-Ahmady El-Naggar, Hassan Moawad, Islam A. Elsehemy, Nancy M. El-Shweihy
Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-18 (2019)
L-asparaginase is a promising enzyme that has a wide range of significant applications including cancer therapy and starchy food industries. The statistical design of Plackett–Burman and face centered central composite design were employed to optim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a547c3d7f28a62b97e7feb98904d121
https://doi.org/10.1038/s41598-019-49709-6
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4
Bioproduction, characterization, anticancer and antioxidant activities of extracellular melanin pigment produced by newly isolated microbial cell factories Streptomyces glaucescens NEAE-H
Autor: Noura El-Ahmady El-Naggar, Sara M. El-Ewasy
Publikováno v: Scientific Reports
In this present study, a newly isolated strain, Streptomyces sp. NEAE-H, capable of producing high amount of black extracellular melanin pigment on peptone-yeast extract iron agar and identified as Streptomyces glaucescens NEAE-H. Plackett–Burman s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e328ca3a0b7742bf752e2c1ac905148a
http://europepmc.org/articles/PMC5307326
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6
Purification, characterization, cytotoxicity and anticancer activities of L-asparaginase, anti-colon cancer protein, from the newly isolated alkaliphilic Streptomyces fradiae NEAE-82
Autor: Sahar F. Deraz, Sara M. El-Ewasy, Hoda M. Soliman, Nehal M. El-Deeb, Noura El-Ahmady El-Naggar
Publikováno v: Scientific Reports
L-asparaginase is an important enzyme as therapeutic agents used in combination with other drugs in the treatment of acute lymphoblastic leukemia. A newly isolated actinomycetes strain, Streptomyces sp. NEAE-82, was potentially producing extracellula
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97788a235ea3ab57bdc9b663354e4169
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7
Identification and statistical optimization of fermentation conditions for a newly isolated extracellular cholesterol oxidase-producing Streptomyces cavourensis strain NEAE-42
Autor: Sara M. El-Ewasy, Nancy M. El-Shweihy, Noura El-Ahmady El-Naggar
Publikováno v: BMC Microbiology
Due to broad range of clinical and industrial applications of cholesterol oxidase, isolation and screening of bacterial strains producing extracellular form of cholesterol oxidase is of great importance. One hundred and thirty actinomycete isolates w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23362c2b58d31c7af0cc222c22af7b3
https://pubmed.ncbi.nlm.nih.gov/27814673
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8
Optimization of Culture Conditions for Production of the Anti-Leukemic Glutaminase Free L-Asparaginase by Newly Isolated Streptomyces olivaceus NEAE-119 Using Response Surface Methodology
Autor: Sara M. El-Ewasy, Nancy M. El-Shweihy, Hassan Moawad, Noura El-Ahmady El-Naggar
Publikováno v: BioMed Research International
BioMed Research International, Vol 2015 (2015)
Among the antitumor drugs, bacterial enzyme L-asparaginase has been employed as the most effective chemotherapeutic agent in pediatric oncotherapy especially for acute lymphoblastic leukemia. Glutaminase free L-asparaginase producing actinomycetes we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6407b2ba1dd7886670261ad352b6ce07
http://europepmc.org/articles/PMC4477217
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9
Erratum to: Identification and statistical optimization of fermentation conditions for a newly isolated extracellular cholesterol oxidase producing Streptomyces cavourensis strain NEAE-42
Autor: Noura El-Ahmady El-Naggar, Nancy M. El-Shweihy, Sara M. El-Ewasy
Publikováno v: BMC Microbiology
Background Due to broad range of clinical and industrial applications of cholesterol oxidase, isolation and screening of bacterial strains producing extracellular form of cholesterol oxidase is of great importance. Results One hundred and thirty acti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42348248db590850af1e9029535186cb
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