Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sara Lusa"'
Autor:
Maria Teresa Di Martino, Virginia Campani, Gabriella Misso, Maria Eugenia Gallo Cantafio, Annamaria Gullà, Umberto Foresta, Pietro Hiram Guzzi, Maria Castellano, Anna Grimaldi, Vincenzo Gigantino, Renato Franco, Sara Lusa, Mario Cannataro, Pierosandro Tagliaferri, Giuseppe De Rosa, Pierfrancesco Tassone, Michele Caraglia
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90005 (2014)
Multiple myeloma (MM) is a disease with an adverse outcome and new therapeutic strategies are urgently awaited. A rising body of evidence supports the notion that microRNAs (miRNAs), master regulators of eukaryotic gene expression, may exert anti-MM
Externí odkaz:
https://doaj.org/article/0957e6cd583246edb275f67115d5f29c
Publikováno v:
Nanomaterials, Vol 6, Iss 7, p 131 (2016)
The growing knowledge on the mechanisms of gene silencing and gene regulation by non-coding RNAs (ncRNA), mainly small interfering RNA (siRNA) and microRNA (miRNA), is providing a significant boost to the development of new therapeutic strategies for
Externí odkaz:
https://doaj.org/article/9c802559713245baba86caa323a3f7a6
Autor:
Marianna Abate, Silvia Zappavigna, Paolo Grieco, Lorena Scotti, Sara Lusa, Ali Munaim Yousif, Virginia Campani, Francesco Merlino, Michele Caraglia, Giuseppe De Rosa, Alessia Maria Cossu, Amalia Luce
Publikováno v:
Journal of Oncology, Vol 2019 (2019)
Journal of Oncology
Journal of Oncology
Urotensin-II (UT-II) and its receptor (UTR) are involved in the occurrence of different epithelial cancers. In particular, UTR was found overexpressed on colon, bladder, and prostate cancer cells. The conjugation of ligands, able to specifically bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd215f6d483d513a0708a4126a4f79b
https://doaj.org/article/8c9e42bf114d4fff87377d9edff74ebe
https://doaj.org/article/8c9e42bf114d4fff87377d9edff74ebe
Autor:
Sara Lusa, Sandra Ristori, Jana Thamm, Paola Luciani, Gina Valentino, Frank Steiniger, Virginia Campani, Isabelle Grillo, Michele Caraglia, Giuseppe De Rosa
Hybrid self-assembling nanoparticles (hsaNPs) encapsulating bisphosphonates (BPs) recently showed very promising results in preclinic experiments for the treatment of brain tumor. However, the poor knowledge on the architecture of hybrid nanovectors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a950cb7fdc423531333980bba10adc59
http://hdl.handle.net/11591/392216
http://hdl.handle.net/11591/392216
Autor:
Manuela Porru, Carlo Leonetti, Carmela Ferri, Sara Lusa, Alessia Maria Cossu, Michele Caraglia, Giuseppe De Rosa, Amalia Luce, Marianna Abate, Silvia Zappavigna
Zoledronic acid (ZOL) is a third generation aminobisphosphonate, commonly used for the treatment of bone metastases. Several studies have shown a direct in vitro antitumor activity of ZOL but a clear evidence of clinical activity is still lacking. Un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dbdc3b4a7be72ba0da67a83b30c7a7
http://hdl.handle.net/11591/424048
http://hdl.handle.net/11591/424048
Autor:
Ornella Gaito, Silvia Zappavigna, Mario De Rosa, Chiara Schiraldi, Sara Lusa, Stefania Porto, Antonella D Agostino, Michele Caraglia, Giuseppe De Rosa, Monica Lamberti
Publikováno v:
Cancer Biology & Therapy. 15:1524-1532
none 10 no Time-lapse live cell imaging is a powerful tool for studying the responses of cells to drugs. Zoledronic acid (ZOL) is the most potent aminobiphosphonate able to induce cell growth inhibition at very low concentrations. The lack of clear e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51163503016adb473e1196d382de85b7
https://doi.org/10.4161/15384047.2014.955989
https://doi.org/10.4161/15384047.2014.955989
Autor:
Giuseppina Salzano, Ivana Campia, Giuseppe De Rosa, Joanna Kopecka, Chiara Riganti, Dario Ghigo, Sara Lusa
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 10:77-87
In this work we investigated how the surface charge and the presence of polyethylene glycol (PEG) on liposome carriers affect the delivery of the encapsulated doxorubicin in P-glycoprotein (Pgp)-overexpressing cells. We found that neutral net charge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b520a42773cf92a83ae04501b747a90
https://doi.org/10.1016/j.nano.2013.06.013
https://doi.org/10.1016/j.nano.2013.06.013
Autor:
Francesco Rossi, Giuseppe De Rosa, Vito de Novellis, Michele Caraglia, Sara Lusa, Alberto Abbruzzese Saccardi, Sabatino Maione, Monica Marra, Francesca Guida, Catia Giordano, Livio Luongo, Giuseppina Salzano, Silvia Zappavigna
Publikováno v:
Molecular Pharmaceutics. 10:1111-1118
In the pathogenesis of neuropathic pain, the conversion of astrocytes in the reactive state and the ras-dependent Erk-mediated pathway play an important role. Zoledronic acid (ZOL) is a potent inhibitor of the latter pathway, but its activity in neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9145852136b1225979a7ab3eaea8fb48
https://doi.org/10.1021/mp3006215
https://doi.org/10.1021/mp3006215
Publikováno v:
Nanomaterials, Vol 6, Iss 7, p 131 (2016)
Nanomaterials
Nanomaterials
The growing knowledge on the mechanisms of gene silencing and gene regulation by non-coding RNAs (ncRNA), mainly small interfering RNA (siRNA) and microRNA (miRNA), is providing a significant boost to the development of new therapeutic strategies for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc3f8156e1f79566484418b4b301137
http://www.mdpi.com/2079-4991/6/7/131
http://www.mdpi.com/2079-4991/6/7/131
Autor:
Giuseppe De Rosa, Michele Caraglia, Chiara Riganti, Vincenzo Desiderio, Sara Lusa, Dario Antonio Ghigo, Elena Gazzano, Antonio Giordano, Martha L. Pinzon-Daza, Giuseppina Salzano, Joanna Kopecka, Stefania Porto
Publikováno v:
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
ResearcherID
Oncotarget
Universidad del Rosario
instacron:Universidad del Rosario
ResearcherID
Oncotarget
The resistance to chemotherapy and the tumor escape from host immunosurveillance are the main causes of the failure of anthracycline-based regimens in breast cancer, where an effective chemo-immunosensitizing strategy is lacking. The clinically used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9542c71f17fec3a250c253aafc30e0
http://hdl.handle.net/11365/997445
http://hdl.handle.net/11365/997445