Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sara Litwak"'
Autor:
Tingting Ge, Amber‐Lee Phung, Gaurang Jhala, Prerak Trivedi, Nicola Principe, David J De George, Evan G Pappas, Sara Litwak, Laura Sanz‐Villanueva, Tara Catterall, Stacey Fynch, Louis Boon, Thomas W Kay, Jonathan Chee, Balasubramanian Krishnamurthy, Helen E Thomas
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 11, Pp n/a-n/a (2022)
Abstract Objectives Immune checkpoint inhibitors have achieved clinical success in cancer treatment, but this treatment causes immune‐related adverse events, including type 1 diabetes (T1D). Our aim was to test whether a JAK1/JAK2 inhibitor, effect
Externí odkaz:
https://doaj.org/article/2f238a260da54aefb12d7ef799742c6b
Autor:
Tingting Ge, Gaurang Jhala, Stacey Fynch, Satoru Akazawa, Sara Litwak, Evan G. Pappas, Tara Catterall, Ishan Vakil, Andrew J. Long, Lisa M. Olson, Balasubramanian Krishnamurthy, Thomas W. Kay, Helen E. Thomas
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cytokines that signal through the JAK-STAT pathway, such as interferon-γ (IFN-γ) and common γ chain cytokines, contribute to the destruction of insulin-secreting β cells by CD8+ T cells in type 1 diabetes (T1D). We previously showed that JAK1/JAK
Externí odkaz:
https://doaj.org/article/39354577fa0840eea6c38e144b21a5dd
Autor:
Isabella Napoli, Sara Litwak, A Dann, Clara Beutner, Bettina Linnartz-Gerlach, V Lepperhof, Marco Prinz, Harald Neumann
Publikováno v:
Gene Therapy. 20:797-806
Inflammation can be prevented in most inflammatory brain diseases, while tissue repair of the lesioned central nervous system (CNS) is still a major challenge. The CNS is difficult to access for protein therapeutics due to the blood-brain barrier. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077e96cb62713ced5389b85e944af8c4
https://doi.org/10.1038/gt.2012.100
https://doi.org/10.1038/gt.2012.100
Publikováno v:
Stroke. 39(10)
Background and Purpose— Systemic injection of hematopoietic stem cells after ischemic cardiac or neural lesions is one approach to promote tissue repair. However, mechanisms of possible protective or reparative effects are poorly understood. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbd7a650cdd88fc43323345f8c64af2
https://pubmed.ncbi.nlm.nih.gov/18658037
https://pubmed.ncbi.nlm.nih.gov/18658037
Autor:
Dorothee von Laer, Sara Litwak, Tsanan Giroglou, Hrvoje Miletic, Yvonne Fischer, Harald Neumann, Werner Stenzel
Publikováno v:
The journal of gene medicine. 9(5)
Early clinical trials for gene therapy of human gliomas with retroviral packaging cells (PC) have been hampered by low transduction efficacy and lack of dissemination of PC within the tumor. In the current approach, these issues have been addressed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a9e9e11e02686cb5fd74bd60423a78
https://pubmed.ncbi.nlm.nih.gov/17474071
https://pubmed.ncbi.nlm.nih.gov/17474071
Autor:
Yannic Waerzeggers, Hrvoje Miletic, Sara Litwak, Andreas H. Jacobs, Martina Deckert, Dorothee von Laer, Uwe Himmelreich, Huongfeng Li, Yvonne Fischer, Alexandra Winkeler, Harald Neumann, Claudia Lange, Werner Stenzel, Tsanan Giroglou
Publikováno v:
Molecular Therapy.
Adult stem cells are promising cellular vehicles for therapy of malignant gliomas as they have the ability to migrate into these tumors and even track infiltrating tumor cells. However, their clinical use is limited by a low passaging capacity that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce11d30812935fcb6527d6816b65a58a
https://doi.org/10.1038/mt.sj.6300155
https://doi.org/10.1038/mt.sj.6300155
Autor:
Sandra Winkeler, Uwe Himmelreich, Harald Neumann, Hrvoje Miletic, Tsanan Giroglou, Werner Stenzel, Dorothee von Laer, Martina Deckert, Sara Litwak, Yvonne Fischer, Andreas H. Jacobs
Publikováno v:
Molecular Therapy. 13
Malignant gliomas still have a dismal prognosis despite advances in neurosurgical resection and adjuvant radio- and chemotherapy. One major reason is their infiltrative growth pattern with single tumor cells migrating distantly from the solid tumor m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956f3bdf2bbfe18d63ba09517d245b4e