Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Sara Linker"'
Autor:
Gerardo Calderon, Alison McRae, Juraj Rievaj, Judith Davis, Inuk Zandvakili, Sara Linker-Nord, Duane Burton, Geoffrey Roberts, Frank Reimann, Bronislava Gedulin, Adrian Vella, Nicholas F LaRusso, Michael Camilleri, Fiona M Gribble, Andres Acosta
Publikováno v:
EBioMedicine, Vol 55, Iss , Pp - (2020)
Background: The bile acid (BA) pathway plays a role in regulation of food intake and glucose metabolism, based mainly on findings in animal models. Our aim was to determine whether the BA pathway is altered and correctable in human obesity and diabet
Externí odkaz:
https://doaj.org/article/81f621a9ddf64e54b9db7c70d00bcc3d
Publikováno v:
Open Biology, Vol 8, Iss 5 (2018)
Personalized medicine has become increasingly relevant to many medical fields, promising more efficient drug therapies and earlier intervention. The development of personalized medicine is coupled with the identification of biomarkers and classificat
Externí odkaz:
https://doaj.org/article/df3140d1fb1f42f68263bc2f33777127
Autor:
Shin-Il Kim, Fabian Oceguera-Yanez, Ryoko Hirohata, Sara Linker, Keisuke Okita, Yasuhiro Yamada, Takuya Yamamoto, Shinya Yamanaka, Knut Woltjen
Publikováno v:
Stem Cell Reports, Vol 4, Iss 4, Pp 727-743 (2015)
As the quintessential reprogramming model, OCT3/4, SOX2, KLF4, and c-MYC re-wire somatic cells to achieve induced pluripotency. Yet, subtle differences in methodology confound comparative studies of reprogramming mechanisms. Employing transposons, we
Externí odkaz:
https://doaj.org/article/8e925940d2314d4eb0a11797eee891ad
Autor:
Sara Linker, Dale J Hedges
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
[This corrects the article DOI: 10.1371/journal.pone.0079402.].
Externí odkaz:
https://doaj.org/article/a93311d770e0491abbe0be041eb1a8ce
Autor:
Sara Linker, Dale J Hedges
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79402 (2013)
Retrotransposons comprise approximately half of the human genome and contribute to chromatin structure, regulatory motifs, and protein-coding sequences. Since retrotransposon insertions can disrupt functional genetic elements as well as introduce new
Externí odkaz:
https://doaj.org/article/810d4ffc900248b08a45a62115970111
Autor:
Dale J Hedges, Toumy Guettouche, Shan Yang, Guney Bademci, Ashley Diaz, Ashley Andersen, William F Hulme, Sara Linker, Arpit Mehta, Yvonne J K Edwards, Gary W Beecham, Eden R Martin, Margaret A Pericak-Vance, Stephan Zuchner, Jeffery M Vance, John R Gilbert
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18595 (2011)
Despite the ever-increasing throughput and steadily decreasing cost of next generation sequencing (NGS), whole genome sequencing of humans is still not a viable option for the majority of genetics laboratories. This is particularly true in the case o
Externí odkaz:
https://doaj.org/article/d75bff2299114a508a1dc92e49cc2928
Autor:
Vijayvargiya, Priya, Camilleri, Michael, Carlson, Paula, Nair, Asha, Nord, Sara Linker, Ryks, Michael, Rhoten, Deborah, Burton, Duane, Busciglio, Irene, Lueke, Alan, Harmsen, W. Scott, Donato, Leslie J.
Publikováno v:
In Clinical Gastroenterology and Hepatology December 2020 18(13):2962-2970
Autor:
Priya Vijayvargiya, Margaret Breen-Lyles, Sara Linker Nord, Daniel Maselli, Irene Busciglio, Ramesh Boinpally, Anna Muslin, Timothy J. Carrothers, Michael Camilleri
Publikováno v:
Digestive Diseases and Sciences. 67:3911-3921
Eluxadoline, a peripherally acting, mixed µ- and κ-opioid receptor (OR) agonist and δ-OR antagonist, is approved for treatment of adults with irritable bowel syndrome-diarrhea (IBS-D). About a third of IBS-D patients has bile acid diarrhea (BAD);
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d177100821c770b3fc99059b1af0f7f
https://doi.org/10.1007/s10620-022-07379-x
https://doi.org/10.1007/s10620-022-07379-x
Autor:
Camilleri, Michael1 (AUTHOR) camilleri.michael@mayo.edu, Nord, Sara Linker1 (AUTHOR), Burton, Duane1 (AUTHOR), Oduyebo, Ibironke1 (AUTHOR), Zhang, Yiming2 (AUTHOR), Chen, Jin3 (AUTHOR), Im, Koeun2 (AUTHOR), Bhad, Prafulla2 (AUTHOR), Badman, Michael K.2 (AUTHOR), Sanders, David S.4 (AUTHOR), Walters, Julian R. F.5 (AUTHOR)
Publikováno v:
Alimentary Pharmacology & Therapeutics. Sep2020, Vol. 52 Issue 5, p808-820. 13p. 1 Diagram, 4 Charts, 4 Graphs.
Autor:
Jin Chen, Ibironke Oduyebo, Michael Camilleri, Michael Badman, Yiming Zhang, Julian R.F. Walters, David S Sanders, Duane Burton, Koeun Im, Sara Linker Nord, Prafulla Bhad
Publikováno v:
Alimentary Pharmacology & Therapeutics. 52:808-820
Background In primary bile acid diarrhoea, feedback by farnesoid X receptor (FXR) and fibroblast growth hormone 19 (FGF19) on hepatic bile acid production is impaired. Aims To evaluate the safety, mechanisms and efficacy of negative feedback by FXR a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161ed1fbfb4ffc1504c18c4daa28de86
https://doi.org/10.1111/apt.15967
https://doi.org/10.1111/apt.15967