Zobrazeno 1 - 10 of 51 pro vyhledávání: '"Sara Lemoinne"'
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Akademický článek
Protective potential of the gallbladder in primary sclerosing cholangitis
Autor: Nora Cazzagon, Ester Gonzalez-Sanchez, Haquima El-Mourabit, Dominique Wendum, Dominique Rainteau, Lydie Humbert, Christophe Corpechot, Olivier Chazouillères, Lionel Arrivé, Chantal Housset, Sara Lemoinne
Publikováno v: JHEP Reports, Vol 5, Iss 4, Pp 100649- (2023)
Background & Aims: Gallbladder enlargement is common in patients with primary sclerosing cholangitis (PSC). The gallbladder may confer hepatoprotection against bile acid overload, through the sequestration and cholecystohepatic shunt of bile acids. T
Externí odkaz: https://doaj.org/article/4757adb6b76b4c48a591d51f829263ac
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2
Akademický článek
Quantitative magnetic resonance cholangiopancreatography metrics are associated with disease severity and outcomes in people with primary sclerosing cholangitis
Autor: Nora Cazzagon, Sanaâ El Mouhadi, Quentin Vanderbecq, Carlos Ferreira, Sarah Finnegan, Sara Lemoinne, Christophe Corpechot, Olivier Chazouillères, Lionel Arrivé
Publikováno v: JHEP Reports, Vol 4, Iss 11, Pp 100577- (2022)
Background & Aims: People with primary sclerosing cholangitis (PSC) have a variable and often progressive disease course that is associated with biliary and parenchymal changes. These changes are typically assessed by magnetic resonance imaging (MRI)
Externí odkaz: https://doaj.org/article/12e7ae2de4b643f988191eedfb567ef6
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3
Akademický článek
ABCB4 variant is associated with hepatobiliary MR abnormalities in people with low-phospholipid-associated cholelithiasis syndrome
Autor: Moustafa Biyoukar, Christophe Corpechot, Sanaâ El Mouhadi, Edouard Chambenois, Quentin Vanderbecq, Véronique Barbu, Catherine Dong, Sara Lemoinne, Mickael Tordjman, Raphel Jomaah, Olivier Chazouilleres, Lionel Arrivé
Publikováno v: JHEP Reports, Vol 4, Iss 11, Pp 100590- (2022)
Background & Aims: The low-phospholipid-associated cholelithiasis (LPAC) syndrome is a recently described peculiar form of cholelithiasis associated with the ATP-binding-cassette subfamily B, member 4 (ABCB4) gene deficiency. The purpose of our study
Externí odkaz: https://doaj.org/article/f64f0d2048c745b396a45b172a7084bd
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4
Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling
Autor: Vincent Quoc-Huy Trinh, Ting-Fang Lee, Sara Lemoinne, Kevin C. Ray, Maria D. Ybanez, Takuma Tsuchida, James K. Carter, Judith Agudo, Brian D. Brown, Kemal M. Akat, Scott L. Friedman, Youngmin A. Lee
Organ homeostasis is maintained by regulated proliferation of distinct cell populations. In mouse liver, cyclin D1-positive hepatocytes in the midlobular zone repopulate the parenchyma at a constant rate to preserve liver homeostasis. The mitogenic c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8637eeac0ec1514a20feba18a720fe50
https://doi.org/10.1101/2023.03.03.531042
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5
Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis
Autor: Lin Lei, Alix Bruneau, Haquima El Mourabit, Justine Guégan, Trine Folseraas, Sara Lemoinne, Tom Hemming Karlsen, Bénédicte Hoareau, Romain Morichon, Ester Gonzalez‐Sanchez, Claire Goumard, Vlad Ratziu, Pierre Charbord, Jérémie Gautheron, Frank Tacke, Thierry Jaffredo, Axelle Cadoret, Chantal Housset
Publikováno v: Hepatology
Hepatology, In press, ⟨10.1002/hep.32456⟩
International audience; Background and Aims: In liver fibrosis, myofibroblasts derive from HSCs and as yet undefined mesenchymal cells. We aimed to identify portal mesenchymal progenitors of myofibroblasts.Approach and Results: Portal mesenchymal cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8bfa4349228cde993649f46f1f361d
https://doi.org/10.1002/hep.32456
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7
New and emerging anti-fibrotic therapeutics entering or already in clinical trials in chronic liver diseases
Autor: Sara Lemoinne, Scott L. Friedman
Publikováno v: Current Opinion in Pharmacology. 49:60-70
Chronic liver diseases with different etiologies represent a major public health issue worldwide. Liver fibrosis is the common feature of almost all chronic liver diseases and remains a key determinant of clinical prognosis. Over the last two decades
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33bcd63a52da63ac4abeda0a13c00ad6
https://doi.org/10.1016/j.coph.2019.09.006
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8
Non-invasive diagnosis and follow-up of autoimmune hepatitis
Autor: Charlotte Bouzbib, M. Bourlière, Alexandra Heurgue, Jérôme Gournay, Christophe Bureau, Sara Lemoinne, Bertrand Hanslik, Victor de Lédinghen, Nathalie Ganne-Carrié, Eric Nguyen-Khac
Publikováno v: Clinics and Research in Hepatology and Gastroenterology
Clinics and Research in Hepatology and Gastroenterology, 2022, 46 (1), ⟨10.1016/j.clinre.2021.101772⟩
Clinics and Research in Hepatology and Gastroenterology, 2022, 46 (1), pp.101772. ⟨10.1016/j.clinre.2021.101772⟩
International audience; Autoimmune hepatitis (AIH) is a liver disease characterised by necrotico-inflammatory lesions of hepatocytes, the presence of specific autoantibodies and response to corticosteroid treatment. AIH must be considered in any pati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b671211d562b184ff2811633f0a73824
https://pubmed.ncbi.nlm.nih.gov/34332126
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9
Gut microbiota in PSC : From association to possible causality. Commentary to 'Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis' by Nakamoto et al., Nature Microbiology, January 2019
Autor: Sara Lemoinne, João Sabino, Harry Sokol
Publikováno v: Clinics and Research in Hepatology and Gastroenterology
Clinics and Research in Hepatology and Gastroenterology, Elsevier, 2020, 44 (2), pp.123-125. ⟨10.1016/j.clinre.2019.06.005⟩
Summary Primary sclerosing cholangitis is a chronic cholestatic liver disease, whose pathogenesis remains poorly understood. Several studies have shown that PSC patients harbor an impaired gut microbiota. A recent study confirmed that PSC patients di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5968afc2b78439b884513fc7b36631d5
https://doi.org/10.1016/j.clinre.2019.06.005
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