Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sara Lecomte"'
Autor:
Grégoire de Streel, Charlotte Bertrand, Nicolas Chalon, Stéphanie Liénart, Orian Bricard, Sara Lecomte, Julien Devreux, Mélanie Gaignage, Gitte De Boeck, Lore Mariën, Inge Van De Walle, Bas van der Woning, Michael Saunders, Hans de Haard, Elien Vermeersch, Wim Maes, Hans Deckmyn, Pierre G. Coulie, Nicolas van Baren, Sophie Lucas
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Inhibiting TGF-β1 to increase immune responses against tumors bears the risk of tumor-promoting toxicity. Here the authors show that selectively blocking TGF-β1 produced by immunosuppressive cells is feasible with anti-GARP:TGF-β1 antibodies and i
Externí odkaz:
https://doaj.org/article/8a55d3ad04c940c5ae3df3fd9a81d1dc
Autor:
Nicolas van Baren, Bas van der Woning, Grégoire de Streel, Gitte De Boeck, Hans Deckmyn, Sara Lecomte, Nicolas Chalon, Elien Vermeersch, Julien Devreux, Inge Van de Walle, Pierre Coulie, Hans de Haard, Mélanie Gaignage, Lore Mariën, Sophie Lucas, Wim Maes, Michael A. Saunders, Stéphanie Liénart, Charlotte Bertrand, Orian Bricard
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature communications, Vol. 11, no.1, p. 4545 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature communications, Vol. 11, no.1, p. 4545 (2020)
TGF-β1, β2 and β3 bind a common receptor to exert vastly diverse effects in cancer, supporting either tumor progression by favoring metastases and inhibiting anti-tumor immunity, or tumor suppression by inhibiting malignant cell proliferation. Glo