Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Sara L. Paulo"'
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Akademický článek
High Caloric Diet Induces Memory Impairment and Disrupts Synaptic Plasticity in Aged Rats
Autor: Sara L. Paulo, Catarina Miranda-Lourenço, Rita F. Belo, Rui S. Rodrigues, João Fonseca-Gomes, Sara R. Tanqueiro, Vera Geraldes, Isabel Rocha, Ana M. Sebastião, Sara Xapelli, Maria J. Diógenes
Publikováno v: Current Issues in Molecular Biology, Vol 43, Iss 3, Pp 2305-2319 (2021)
The increasing consumption of sugar and fat seen over the last decades and the consequent overweight and obesity, were recently linked with a deleterious effect on cognition and synaptic function. A major question, which remains to be clarified, is w
Externí odkaz: https://doaj.org/article/c7b70d863682401eac2ab9dee32953d3
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2
Akademický článek
Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology
Autor: Rui S. Rodrigues, Diogo M. Lourenço, Sara L. Paulo, Joana M. Mateus, Miguel F. Ferreira, Francisco M. Mouro, João B. Moreira, Filipa F. Ribeiro, Ana M. Sebastião, Sara Xapelli
Publikováno v: Molecules, Vol 24, Iss 7, p 1350 (2019)
With the increase of life expectancy, neurodegenerative disorders are becoming not only a health but also a social burden worldwide. However, due to the multitude of pathophysiological disease states, current treatments fail to meet the desired outco
Externí odkaz: https://doaj.org/article/0d48ce5ecb2b492c99ff1ec4799cabea
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3
Sustained Hippocampal Neural Plasticity Questions the Reproducibility of an Amyloid-β-Induced Alzheimer’s Disease Model
Autor: Sara Xapelli, João Fonseca-Gomes, Ana M. Sebastião, Susana Solá, Filipa F Ribeiro, Rui S Rodrigues, Rita Soares, Maria José Diógenes, Joana M Mateus, Sara L Paulo, Leonor Ribeiro-Rodrigues
Publikováno v: Journal of Alzheimer's Disease. 82:1183-1202
Background: The use of Alzheimer’s disease (AD) models obtained by intracerebral infusion of amyloid-β (Aβ) has been increasingly reported in recent years. Nonetheless, these models may present important challenges. Objective: We have focused on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394254ae220156485ad320f5ffaa4c8b
https://doi.org/10.3233/jad-201567
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4
Adult Neural Stem Cells as Promising Targets in Psychiatric Disorders
Autor: Sara L Paulo, João B Moreira, Ana M. Sebastião, Sara R. Tanqueiro, Sara Xapelli, Rui S Rodrigues, Maria José Diógenes
Publikováno v: Stem Cells and Development. 29:1099-1117
The development of new therapies for psychiatric disorders is of utmost importance, given the enormous toll these disorders pose to society nowadays. This should be based on the identification of neural substrates and mechanisms that underlie disease
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641f0d41e7ce3d6d2825b9d2cf7efa99
https://doi.org/10.1089/scd.2020.0100
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5
Adult hippocampal neurogeneris and amyloid-ß: reproducibility of a sporadic Alzheimer's disease model
Autor: João Fonseca-Gomes, Leonor Ribeiro-Rodrigues, Joana M Mateus, Filipa F Ribeiro, Ana M. Sebastião, Susana Solá, Sara Xapelli, Sara L Paulo, Rui S Rodrigues, Maria José Diógenes
Late-onset sporadic Alzheimers disease (AD) is the most common neurodegenerative disorder worldwide, yet present treatment options are still very limited. Modulating adult hippocampal neurogenesis (AHN) as a potential therapeutic target for AD has be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70b1815a73ac5029b531fb4c3fe352d7
https://doi.org/10.14293/s2199-1006.1.sor-.pp5moih.v1
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6
Boosting postnatal oligodendrogenesis in a mouse model of Multiple Sclerosis
Autor: Rita Soares, Sara L Paulo, Joana M Mateus, Marta Gomes, Ângelo F. Chora, Ana M. Sebastião, Sara Xapelli
Under Multiple Sclerosis pathological conditions, oligodendrocyte precursor cells (OPCs) present in the brain parenchyma or derived from subventricular zone neural stem cells (SVZ-NSCs) can differentiate into oligodendrocytes (OLs), which migrate and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a1025b12270e20146f7ddcc7873614c
https://doi.org/10.14293/s2199-1006.1.sor-.ppeipfk.v1
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8
Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology
Autor: João B Moreira, Sara L Paulo, Francisco M. Mouro, Joana M Mateus, Diogo M Lourenço, Filipa F Ribeiro, Rui S Rodrigues, Ana M. Sebastião, Sara Xapelli, Miguel F Ferreira
Publikováno v: Molecules, Vol 24, Iss 7, p 1350 (2019)
Molecules
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
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© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
With
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90c183c2792ea501932c2b7d9035916
https://www.mdpi.com/1420-3049/24/7/1350
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