Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Sara L Zimmer"'
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244858 (2021)
In this study, hierarchies of probabilistic models are evaluated for their ability to characterize the untemplated addition of adenine and uracil to the 3' ends of mitochondrial mRNAs of the human pathogen Trypanosoma brucei, and for their generative
Externí odkaz:
https://doaj.org/article/e18d4c6a47c04bf1b14ec8b922d9dcad
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197983 (2018)
The insect-transmitted protozoan parasite Trypanosoma cruzi experiences changes in nutrient availability and rate of flux through different metabolic pathways across its life cycle. The species encompasses much genetic diversity of both the nuclear a
Externí odkaz:
https://doaj.org/article/67633d440cc1492482b1621b14764aed
Autor:
Aygul Ishemgulova, Natalya Kraeva, Jana Hlaváčová, Sara L Zimmer, Anzhelika Butenko, Lucie Podešvová, Tereza Leštinová, Julius Lukeš, Alexei Kostygov, Jan Votýpka, Petr Volf, Vyacheslav Yurchenko
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 7, p e0005782 (2017)
Leishmania virulence factors responsible for the complicated epidemiology of the various leishmaniases remain mainly unidentified. This study is a characterization of a gene previously identified as upregulated in two of three overlapping datasets co
Externí odkaz:
https://doaj.org/article/c478850c63dc4a47830ffbfb1b534dea
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37639 (2012)
Short, non-encoded oligo(A), oligo(U), or A/U tails can impact mRNA stability in kinetoplastid mitochondria. However, a comprehensive picture of the relative effects of these modifications in RNA stability is lacking. Furthermore, while the U-preferr
Externí odkaz:
https://doaj.org/article/3176a9c632684d63ade1b8e6b4170e78
Autor:
Amanda T. S. Albanaz, Mark Carrington, Alexander O. Frolov, Anna I. Ganyukova, Evgeny S. Gerasimov, Alexei Y. Kostygov, Julius Lukeš, Marina N. Malysheva, Jan Votýpka, Alexandra Zakharova, Kristína Záhonová, Sara L. Zimmer, Vyacheslav Yurchenko, Anzhelika Butenko
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Protists of the family Trypanosomatidae (phylum Euglenozoa) have gained notoriety as parasites affecting humans, domestic animals, and agricultural plants. However, the true extent of the group's diversity spreads far beyond the m
Externí odkaz:
https://doaj.org/article/1ccbe175e908488286a6ce1d72afa3ae
Autor:
Clara M. Smoniewski, Poorya Mirzavand Borujeni, Marshall Hampton, Austin Petersen, Sean P. Faacks, Reza Salavati, Sara L. Zimmer
Publikováno v:
Frontiers in Parasitology, Vol 2 (2024)
RNA-specific nucleotidyltransferases (rNTrs) add nontemplated nucleotides to the 3′ end of RNA. Two noncanonical rNTRs that are thought to be poly(A) polymerases (PAPs) have been identified in the mitochondria of trypanosomes – KPAP1 and KPAP2. K
Externí odkaz:
https://doaj.org/article/ca87d01f0a284f7d9e9bef107d3fec72
Autor:
Clara M. Smoniewski, Poorya Mirzavand Borujeni, Austin Petersen, Marshall Hampton, Reza Salavati, Sara L. Zimmer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Since the first identification of circular RNA (circRNA) in viral-like systems, reports of circRNAs and their functions in various organisms, cell types, and organelles have greatly expanded. Here, we report the first evidence, to our knowle
Externí odkaz:
https://doaj.org/article/5499c1d696994ab49e5382be8a098c76
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 8, Iss 8, p 384 (2023)
Instability is an intriguing characteristic of many protist genomes, and trypanosomatids are not an exception in this respect. Some regions of trypanosomatid genomes evolve fast. For instance, the trypanosomatid mitochondrial (kinetoplast) genome con
Externí odkaz:
https://doaj.org/article/e30119c1956249378cfda35dc4de8c18
Autor:
Amanda Termuhlen, Jerica M. Berge, Jakub Tolar, Sophie Watson, Heather Dorr, Snigdha Pusalavidyasagar, Kait C. Macheledt, Alicia Kunin-Batson, Rebekah Pratt, Sara L Zimmer
Publikováno v:
Academic Medicine. 97:370-377
Many medical schools are instituting gender equity initiatives to address long-standing inequities (e.g., salary, leadership positions, resource distribution) between women and men in academic medicine. However, few theory-driven models exist with bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed18f8e554da9812666d5a89caedaac
https://doi.org/10.1097/acm.0000000000004375
https://doi.org/10.1097/acm.0000000000004375
Autor:
Clara M. Smoniewski, Poorya Mirzavand Borujeni, Austin Petersen, Marshall Hampton, Reza Salavati, Sara L. Zimmer
Publikováno v:
bioRxiv
Since the first identification of circular RNA (circRNA) in viral-like systems, reports of circRNAs and their functions in various organisms, cell types, and organelles have greatly expanded. Here, we report the first evidence of circular mRNA in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e545979110a6034eebc47e88d0fd2e
https://doi.org/10.1101/2023.02.10.528059
https://doi.org/10.1101/2023.02.10.528059
