Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sara L Sampson"'
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215218 (2019)
Poor solute transport through the cartilage endplate (CEP) impairs disc nutrition and could be a key factor that limits the success of intradiscal biologic therapies. Here we demonstrate that treating the CEP with matrix metalloproteinase-8 (MMP-8) r
Externí odkaz:
https://doaj.org/article/2d73efca4a9845d7b36f8f8984bd4c6e
Publikováno v:
Journal of Biomechanics. 83:273-279
Nutrient and metabolite transport through the cartilage endplate (CEP) is important for maintaining proper disc nutrition, but the mechanisms of solute transport remain unclear. One unresolved issue is the role of dynamic loading. In comparison to st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0d382460a6ee5a08e89f920a1ec72d
https://doi.org/10.1016/j.jbiomech.2018.12.004
https://doi.org/10.1016/j.jbiomech.2018.12.004
Autor:
A. Ouyang, Ann A. Lazar, Sara L. Sampson, Aaron J. Fields, Jason Wong, Jeffrey C. Lotz, H. Bell-Briones
Publikováno v:
Osteoarthritis Cartilage
Osteoarthritis and cartilage, vol 27, iss 6
Osteoarthritis and cartilage, vol 27, iss 6
Summary Objective Intradiscal biologic therapy is a promising strategy for managing intervertebral disc degeneration. However, these therapies require a rich nutrient supply, which may be limited by the transport properties of the cartilage endplate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eab68c06d35bb34f9dcf9df8a505733
https://europepmc.org/articles/PMC6536352/
https://europepmc.org/articles/PMC6536352/
Autor:
Ann A. Lazar, Aaron J. Fields, Sara L. Sampson, Jeffrey C. Lotz, Aaron Dolor, Francis C. Szoka
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215218 (2019)
PloS one, vol 14, iss 4
PloS one, vol 14, iss 4
Poor solute transport through the cartilage endplate (CEP) impairs disc nutrition and could be a key factor that limits the success of intradiscal biologic therapies. Here we demonstrate that treating the CEP with matrix metalloproteinase-8 (MMP-8) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b349275990613ff5a362a308bfed9e
https://doaj.org/article/2d73efca4a9845d7b36f8f8984bd4c6e
https://doaj.org/article/2d73efca4a9845d7b36f8f8984bd4c6e